Development of a stepwise [3 + 3] annelation to functionalized piperidines

Organic Letters

Volumn 7, Issue 14, 2005, Pages 2993-2996

  Goodenoug, Katharine M ^a   Raubo, Piotr ^b   Harrity, Joseph P A ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 22244488092     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol050965t     Document Type: Article

References (15)

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2. (b) Hedley, S. J.; Moran, W. J.; Price, D. A.; Harrity, J. P. A. J. Org. Chem. 2003, 68, 4286.
3. For reviews of alternative [3 + 3] approaches to piperidine systems, see: (a) Harrity, J. P. A.; Provoost, O. Org. Bio. Chem. 2005, 1349.
4. (b) Hsung, R. P.; Kurdyumov, A. V.; Sydorenko, N. Eur. J. Org. Chem 2005, 23.
5. Craig, D.; Berry, M. B. Synlett 1992, 41.
6. For a review of Pd-TMM cycloadditions see: (a) Trost, B. M. Angew. Chem., Int. Ed. Engl. 1986, 25, 1.
7. Trost, B. M.; Chan, D. M. T.; Nanninga, T. M. Org. Synth 1984, 62, 58.
8. Addition of a related Grignard reagent to epoxides has been shown to produce pyrans: van der Louw, J.; van der Baan, J. L.; Out, G. J. J.; de Kanter, F. J. J.; Bickelhaupt, F.; Klumpp, G. W. Tetrahedron 1992, 48, 9901.
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