-
1
-
-
0033625089
-
The novel NK1 receptor antagonist MK-0869 (L-764-030) and its water soluble phosphoryl prodrug, L-758298, inhibit acute and delayed cisplatin-induced emesis in ferrets
-
Tattersall FD, Rycroft W, Cumberbatch M, et al. The novel NK1 receptor antagonist MK-0869 (L-764-030) and its water soluble phosphoryl prodrug, L-758298, inhibit acute and delayed cisplatin-induced emesis in ferrets. Neuropharmacology 2000; 39: 652-63
-
(2000)
Neuropharmacology
, vol.39
, pp. 652-663
-
-
Tattersall, F.D.1
Rycroft, W.2
Cumberbatch, M.3
-
2
-
-
0033590464
-
Reduction in cisplatin-induced emesis by a selective neurokinin-1- receptor antagonist
-
L-754-030 Antiemetic Trials Group
-
Navari RM, Reinhardt RR, Gralla RJ, et al. Reduction in cisplatin-induced emesis by a selective neurokinin-1-receptor antagonist. L-754-030 Antiemetic Trials Group. N Engl J Med 1999; 340: 190-5
-
(1999)
N Engl J Med
, vol.340
, pp. 190-195
-
-
Navari, R.M.1
Reinhardt, R.R.2
Gralla, R.J.3
-
3
-
-
0035868769
-
Prevention of cisplatin-induced emesis by the oral neurokinin-1 antagonist: MK-069, in combination with granisetron and dexamethasone or with dexamethasone alone
-
Campos D, Pereira JR, Reinhardt RR, et al. Prevention of cisplatin-induced emesis by the oral neurokinin-1 antagonist: MK-069, in combination with granisetron and dexamethasone or with dexamethasone alone. J Clin Oncol 2001; 19: 2971-94
-
(2001)
J Clin Oncol
, vol.19
, pp. 2971-2994
-
-
Campos, D.1
Pereira, J.R.2
Reinhardt, R.R.3
-
4
-
-
0038728753
-
Addition of the neurokinin 1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting: Results from a randomized, double-blind, placebo controlled trial in Latin America
-
Poli-Bigelli S, Rodrigues-Pereira J, Carides AD, et al. Addition of the neurokinin 1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting: results from a randomized, double-blind, placebo controlled trial in Latin America. Cancer 2003; 97 (12): 2090-8
-
(2003)
Cancer
, vol.97
, Issue.12
, pp. 2090-2098
-
-
Poli-Bigelli, S.1
Rodrigues-Pereira, J.2
Carides, A.D.3
-
5
-
-
0021089409
-
Consequences of renal insufficiency on the hepatic clearance of some drugs
-
Balant LP, Dayer P, Fabre J. Consequences of renal insufficiency on the hepatic clearance of some drugs. Int J Clin Pharm Res 1983; 3 (6): 459-74
-
(1983)
Int J Clin Pharm Res
, vol.3
, Issue.6
, pp. 459-474
-
-
Balant, L.P.1
Dayer, P.2
Fabre, J.3
-
6
-
-
0034023147
-
Effect of chronic renal failure on the disposition of highly hepatically metabolized drugs
-
Yuan R, Venitz J. Effect of chronic renal failure on the disposition of highly hepatically metabolized drugs. Int J Clin Pharmacol Res 2000; 38 (5): 245-53
-
(2000)
Int J Clin Pharmacol Res
, vol.38
, Issue.5
, pp. 245-253
-
-
Yuan, R.1
Venitz, J.2
-
7
-
-
0025302891
-
Disease-induced variations in plasma protein levels: Implications for drug dosage regimens (Pt I)
-
Zini R, Riant P, Barre J, et al. Disease-induced variations in plasma protein levels: implications for drug dosage regimens (Pt I). Clin Pharmacokinet 1990; 19: 147-59
-
(1990)
Clin Pharmacokinet
, vol.19
, pp. 147-159
-
-
Zini, R.1
Riant, P.2
Barre, J.3
-
8
-
-
0025182993
-
Disease-induced variations in plasma protein levels: Implications for drug dosage regimens (Pt II)
-
Zini R, Riant P, Barre J, et al. Disease-induced variations in plasma protein levels: implications for drug dosage regimens (Pt II). Clin Pharmacokinet 1990; 19: 218-29
-
(1990)
Clin Pharmacokinet
, vol.19
, pp. 218-229
-
-
Zini, R.1
Riant, P.2
Barre, J.3
-
9
-
-
0344453817
-
Pharmacokinetics of rosiglitazone in patients with varying degrees of renal insufficiency
-
Chapelsky MC, Thompson-Culkin K, Miller AK, et al. Pharmacokinetics of rosiglitazone in patients with varying degrees of renal insufficiency. J Clin Pharm 2003; 43 (3): 252-9
-
(2003)
J Clin Pharm
, vol.43
, Issue.3
, pp. 252-259
-
-
Chapelsky, M.C.1
Thompson-Culkin, K.2
Miller, A.K.3
-
10
-
-
0035047223
-
The pharmacokinetics of cerivastatin in patients on chronic hemodialysis
-
Muck W, Park S, Jager W, et al. The pharmacokinetics of cerivastatin in patients on chronic hemodialysis. Int J Clin Pharmacol Ther 2001; 39 (5): 192-8
-
(2001)
Int J Clin Pharmacol Ther
, vol.39
, Issue.5
, pp. 192-198
-
-
Muck, W.1
Park, S.2
Jager, W.3
-
11
-
-
0033983513
-
Pharmacokinetics of mycophenolic acid in renal insufficiency
-
Meier-Kriesche HU, Shaw LM, Korecka M, et al. Pharmacokinetics of mycophenolic acid in renal insufficiency. Ther Drug Monit 2000; 22 (1): 27-30
-
(2000)
Ther Drug Monit
, vol.22
, Issue.1
, pp. 27-30
-
-
Meier-Kriesche, H.U.1
Shaw, L.M.2
Korecka, M.3
-
12
-
-
0031882169
-
Pharmacokinetics and protein binding of eprosartan in healthy volunteers and in patients with varying degrees of renal impairment
-
Martin DE, Chapelsky MC, Ilson B, et al. Pharmacokinetics and protein binding of eprosartan in healthy volunteers and in patients with varying degrees of renal impairment. J Clin Pharmacol 1998; 38 (2): 129-37
-
(1998)
J Clin Pharmacol
, vol.38
, Issue.2
, pp. 129-137
-
-
Martin, D.E.1
Chapelsky, M.C.2
Ilson, B.3
-
13
-
-
0036218554
-
Changes in plasma protein binding have little clinical relevance
-
Benet LZ, Hoener BA. Changes in plasma protein binding have little clinical relevance. Pharmacol Ther 2002; 71 (3): 115-21
-
(2002)
Pharmacol Ther
, vol.71
, Issue.3
, pp. 115-121
-
-
Benet, L.Z.1
Hoener, B.A.2
-
14
-
-
0036122678
-
The effects of age and renal and hepatic impairment on the pharmacokinetics of sildenafil
-
Muirhead GJ, Wilner K, Colburn W, et al. The effects of age and renal and hepatic impairment on the pharmacokinetics of sildenafil. Br J Clin Pharmacol 2002; 53 Suppl. 1: 21-30S
-
(2002)
Br J Clin Pharmacol
, vol.53
, Issue.1 SUPPL.
-
-
Muirhead, G.J.1
Wilner, K.2
Colburn, W.3
-
15
-
-
0023251121
-
Cyclosporin: Measurement of fraction unbound in plasma
-
Aug
-
Legg B, Rowland M. Cyclosporin: measurement of fraction unbound in plasma. J Pharm Pharmacol 1987 Aug; 39 (8): 599-603
-
(1987)
J Pharm Pharmacol
, vol.39
, Issue.8
, pp. 599-603
-
-
Legg, B.1
Rowland, M.2
-
16
-
-
32744467488
-
-
West Point (PA): Merck & Co., Inc. (Data on file)
-
A double-blind, double-dummy, parallel, randomized, placebo-controlled study to investigate the pharmacokinetics, safety and tolerability of multiple doses of MK-0869 (125 and 375 mg/day) in healthy young subjects. West Point (PA): Merck & Co., Inc. (Data on file)
-
A Double-blind, Double-dummy, Parallel, Randomized, Placebo-controlled Study to Investigate the Pharmacokinetics, Safety and Tolerability of Multiple Doses of MK-0869 (125 and 375 mg/day) in Healthy Young Subjects
-
-
-
17
-
-
0037403701
-
Establishing the dose of the oral NK1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting
-
Chawla SP, Grunberg SM, Gralla RJ, et al. Establishing the dose of the oral NK1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting. Cancer 2003; 97 (9): 2290-300
-
(2003)
Cancer
, vol.97
, Issue.9
, pp. 2290-2300
-
-
Chawla, S.P.1
Grunberg, S.M.2
Gralla, R.J.3
-
18
-
-
0031015510
-
Principles of drug administration in renal insufficiency
-
Lam YWF, Banerji S, Hatfield C, et al. Principles of drug administration in renal insufficiency. Clin Pharmacokinet 1997; 32: 30-57
-
(1997)
Clin Pharmacokinet
, vol.32
, pp. 30-57
-
-
Lam, Y.W.F.1
Banerji, S.2
Hatfield, C.3
-
19
-
-
32744475079
-
-
EMEND® product information [online]. Available from URL: http://www.emend.com/emend/shared/documents/pi.pdf [Accessed 2005 Apr 8]
-
Product Information [Online]
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