Effect of sedation with midazolam or propofol on patient's comfort during cancer chemotherapy infusion: A prospective, randomized, double-blind study in breast cancer patients

Journal of Chemotherapy

Volumn 17, Issue 3, 2005, Pages 327-333

  Mentes, S Dikmen ^a   Unsal, Diclehan ^b,c   Baran, O ^a   Argun, G ^a   Ertunc, F N ^a  

^a ANKARA ONCOLOGY HOSPITAL   (Turkey)

^b GAZI UNIVERSITY FACULTY OF MEDICINE   (Turkey)

^c NONE   (Turkey)

Author keywords

Chemotherapy; Midazolam; Patient's comfort; Propofol; Sedation; Supportive care

Indexed keywords

CYCLOPHOSPHAMIDE; FLUOROURACIL; METHOTREXATE; MIDAZOLAM; ONDANSETRON; PROPOFOL;

ADULT; ANXIETY; ARTICLE; BREAST CANCER; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; NAUSEA; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SEDATION; VOMITING;

EID: 22244459888     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.2005.17.3.327     Document Type: Article

References (22)

1. Morrow GR, Morrell C. Behavioral treatment for anticipatory nausea and vomiting induced by cancer chemotherapy. N Engl J Med 1982; 307(24): 1476-1480.
2. Laszlo J, Clark RA, Hanson DC, Tyson L, Crumpler L, Grallar R. Lorazepam in cancer patients treated with cisplatin: a drug having antiemetic, amnesic and anxiolytic effects. J Clin Oncol 1985; 3(6): 864-869.
3. Reves JG, Fragen RJ, Vinik HR, Greenblat DJ. Midazolam: Pharmacology and uses. Anesthesiology 1985; 62(3): 310-324.
4. Zacny JP, Lichtor JLL, Coalson DW, et al. Subjective and psychomotor effects of subanesthetic doses of propofol in healthy volunteers. Anesthesiology 1992; 76(5): 696-702.
5. Borgeat A, Wilder-Smith OH, Forni M, Suter PM. Adjuvant propofol enables better control of nausea and emesis secondary to chemotherapy for breast cancer. Can J Anaesth 1994; 41(11): 1117-1119.
6. Olynyk JK, Cullen SR, Leahy MF. Midazolam: an effective antiemetic agent for cytotoxic chemotherapy. Med J Aust 1989; 150(8): 466.
7. Potanovich LM, Pisters KM, Kris MG, et al. Midazolam in patients receiving anticancer chemotherapy and antiemetics. J Pain Symptom Manage 1993; 8(8): 519-524.
8. Prasad V, Till CB, Smith A. Midazolam, an anti-emetic? Anaesthesia 2002; 57(4): 415.
9. Scher CS, Amar D, McDowall RH, Barst SM. Use of propofol for the prevention of chemotherapy-induced nausea and emesis in oncology patients. Can J Anaesth 1992; 39(2): 170-172.
10. Tomioka S, Kurio T, Takaishi K, Nakajo N. Propofol is effective in chemotherapy induced nausea and vomiting: a case report with quantitative analysis. Anesth Analg 1999; 89(3): 798-799.
11. Mackenzie N, Grant IS. Propofol for intravenous sedation. Anaesthesia 1987; 42(1): 3-6.
12. Oddby-Muhrbeck E, Eksborg S, Bergendahl HT, Muhrbeck O, Lonqvist PA. Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery. Anesthesiology 2002; 96(5): 1109-1114.
13. Bethune DW. Test of delayed memory recall suitable for assessing postoperative amnesia. Anaesthesia 1981; 36(10): 942-948.
14. DiLorenzo TA, Jacobsen PB, Bovbjerg DH, et al. Sources of anticipatory emotional distress in women receiving chemotherapy for breast cancer. Ann Oncol 1995; 6(7): 705-711.
15. Andrykowski MA, Redd WH. Longitudinal analysis of the development of anticipatory nausea. J Consult Clin Psychol 1987; 55(1): 36-41.
16. Bishop JF, Olver IN, Wolf MM, et al. Lorazepam: A randomized, double-blind, crossover study of a new antiemetic in patients receiving cytotoxic chemotherapy and prochloroperazine. J Clin Oncol 1984; 2(6): 691-695.
17. Greenberg DB, Surman OS, Clarke J, et al. Alprazolam for phobic nausea and vomiting related to cancer chemotherapy. Cancer Treat Rep 1987; 71: 549-550.
18. Snellen F, Lauwers P, Demeyere R, Byttebier G, Van Aken H. The use of midazolam versus propofol for short-term sedation following coronary artery bypass grafting. Intensive Care Med 1990; 16(5): 312-316.
19. Treish I, Shord S, Valgus J, et al. Randomized double-blind study of the Reliefband as an adjunct to standard antiemetics in patients receiving moderately-high to highly emetogenic chemotherapy. Support Care Cancer 2003; 11(8): 516-521.
20. DiFlorio T, Goucke CR. The effect of midazolam on persistent postoperative nausea and vomiting. Anaesth Intensive Care 1999; 27(1): 38-40.
21. Phillis JW, Bender AS, Wu PH. Benzodiazepines inhibit adenosine uptake into rat brain synaptosomes. Brain Res 1980; 195(2): 494-498.
22. Takada K, Murai T, Kanayama T, Koshikawa N. Effects of midazolam and flunitrazepam on the release of dopamine from rat striatum measured by in vivo microdialysis. Br J Anaesth 1993; 70(2): 181-185.