Maternal obesity and the risk for orofacial clefts in the offspring

Cleft Palate-Craniofacial Journal

Volumn 42, Issue 4, 2005, Pages 367-371

  Cedergren, Marie ^a,c   Källén, Bengt ^b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b UNIVERSITY OF LUND   (Sweden)

^c LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Body mass index; Cleft lip; Cleft palate; Epidemiology

Indexed keywords

ADULT; ARTICLE; BODY MASS; CLEFT LIP; CLEFT PALATE; CONTROLLED STUDY; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MATERNAL AGE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PARITY; PRIORITY JOURNAL; PROGENY; RISK FACTOR; SMOKING;

ADULT; BODY MASS INDEX; CLEFT LIP; CLEFT PALATE; CONFOUNDING FACTORS (EPIDEMIOLOGY); FEMALE; HUMANS; INFANT, NEWBORN; OBESITY; ODDS RATIO; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY TRIMESTER, FIRST; REGISTRIES; RISK FACTORS; SWEDEN;

EID: 22244433485     PISSN: 10556656     EISSN: None     Source Type: Journal    
DOI: 10.1597/04-012.1     Document Type: Article

References (28)

1. Åberg A, Westbom L, Källén B. Congenital malformations among infants whose mothers had gestational diabetes or preexisting diabetes. Early Hum Dev. 2001;61:85-95.
2. Cedergren MI, Källén BA. Maternal obesity and infant heart defects. Obes Res. 2003;11:1065-1071.
3. Cnattingius S, Ericson A, Gunnarskog J, Källén B. A quality study of a medical birth registry. Scand J Soc Med. 1990;18:143-148.
4. Czeizel AE, Timar L, Sakozi A. Dose-dependent effects of folic acid on the prevention of orofacial clefts. Pediatrics. 1999;56:335-340.
5. Institute of Medicine. Nutrition During Pregnancy. Part I: weight gain; part 2: nutrient supplements. Washington, DC: National Academy Press: 1990.
6. Itikala PR, Watkins ML, Mulinare J, Moore CA, Liu Y. Maternal multivitamin use and orofacial clefts in offspring. Teratology. 2001;63:79-86.
7. Källén, B. Maternal drug use and infant cleft lip/palate with special reference to corticoids. Cleft Palate Craniofac J. 2003;40:624-628.
8. Källén BA, Otterblad Olausson P. Use of folic acid and delivery outcome: a prospective study. Reprod Toxicol. 2002;16:327-332.
9. Källén B, Winberg J. A Swedish register of congenital malformations. Experience with continuous registration during 2 years with special reference to multiple malformations. Pediatrics. 1968;41:765-776.
10. Källén K. Maternal smoking and orofacial clefts. Cleft Palate Craniofac J. 1997;34:11-16.
11. Källén K. Maternal smoking, body mass index, and neural tube defects. Am J Epidemiol. 1998;147:1103-1111.
12. Lissner L, Johansson SE, Qvist J, Rossner S, Wolk A., Social mapping of the obesity epidemic in Sweden. Int J Obes Relat Metab Disord. 2000;24:801-805.
13. Mantel N, Haenszel W. Statistical aspects of the analyses of data from retrospective studies of disease. J Natl Cancer Inst. 1959;22:719-748.
14. Miettinen OS. Simple interval estimation of risk ratio. Am J Epidemiol. 1974; 100:515-516.
15. Moore LL, Singer MR, Bradlee ML, Rothman KJ, Milunsky A. A prospective study of the risk of congenital defects associated with maternal obesity and diabetes mellitus. Epidemiology. 2000;11:689-694.
16. National Board of Health and Welfare. The Swedish Medical Birth Register-a summary of content and quality. Available at: http://www.sos.se/ FULLTEXT/112/2003-112-3/2003-112-3.pdf.
17. The Swedish Hospital Discharge register. Available at: http://www.sos.se/English/ParEng.htm. Accessed 2003.
18. Queisser-Luft A, Kienger-Baum D, Menger H, Stolz G, Schlaefer K, Merz E. Does maternal obesity increase the risk of fetal abnormalities? Analysis of 20,248 newborn infants of the Mainz Birth Register for detecting congenital abnormalities. Ultraschall Med. 1998;19:40-44.
19. Scheen AJ, Paquot N, Lethiexhe MR, Paolisso G, Castillo MJ, Lefebvre PJ. Glucose metabolism in obese subjects: lessons from OGTT, IVGTT and clamp studies. Int J Obes Relat Metab Disord. 1995;19:S14-S20.
20. Shaw GM, Lammer EJ, Wasserman CR, O'Malley CD, Tolarova MM. Risks of orofacial clefts in children born to women using multivitamins containing folic acid periconceptionally. Lancet. 1995;346:393-396.
21. Shaw GM, Todoroff K, Schaffer DM, Selvin S. Maternal height and prepregnancy body mass index as risk factors for selected congenital anomalies. Paediatr Perinat Epidemiol. 2000;14:234-239.
22. Shaw GM, Velie EM, Schaffer D. Risk of neural tube defect-affected pregnancies among obese women. JAMA. 1996;275:1093-1096.
23. Spilson SV, Kim HJ, Chung KC. Association between maternal diabetes mellitus and newborn oral cleft. Ann Plast Surg. 2001;47:477-481.
24. Waller DK, Mills JL, Simpson JL, Cunningham GC, Conley MR, Lassman MR, Rhoads GG. Are obese women at higher risk for producing malformed offspring? Am J Obstet Gynecol. 1994;170:541-548.
25. Watkins ML, Botto LD. Maternal prepregnancy weight and congenital heart defects in offspring. Epidemiology. 2001;12:439-446.
26. Watkins ML, Rasmussen SA, Honein MA, Botto LD, Moore CA. Maternal obesity and risk for birth defects. Pediatrics. 2003;111:1152-1158.
27. Wyszynski DF, Beaty TH. Review of the role of potential teratogens in the origin of human nonsyndromic oral clefts. Teratology. 1996;53:309-317.
28. Wyszynski DF, Duffy DL, Beaty TH. Maternal cigarette smoking and oral clefts: a meta-analysis. Cleft Palate Craniofac J. 1997;34:206-210.