The molecular adsorbent recycling system (MARS) and transmembrane transport of albumin-bound toxins (multiple letters)

Liver Transplantation

Volumn 11, Issue 7, 2005, Pages 853-854

  Evenepoel, Pieter ^a   Bammens, Bert ^a   Nevens, Frederik ^a   Wilmer, Alexander ^a   Vanrenterghem, Yres ^a   Jalan, Rajiv ^b   Sen, Sambit ^b   Steiner, Christian ^b  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BILE ACID; BILIRUBIN; TOXIN;

ADULT; ARTIFICIAL KIDNEY; BLOOD SAMPLING; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIALYSATE; DIALYSIS; FEMALE; HUMAN; LETTER; LIVER FAILURE; MALE; MEMBRANE TRANSPORT; MOLECULAR ADSORBENT RECYCLING SYSTEM; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

EID: 22144496090     PISSN: 15276465     EISSN: None     Source Type: Journal    
DOI: 10.1002/lt.20450     Document Type: Letter

References (6)

1. 1 Steiner C, Sen S, Stange J, Williams R, Jalan R. Binding of bilirubin and bromosulphthalein to albumin: implications for understanding the pathophysiology of liver failure and its management. Liver Transpl 2004 ; 10: 1531–1538.
2. 2 Meyer TW, Leeper EC, Bartlett DW, Depner TA, Lit YZ, Robertson CR, Hostetter TH. Increasing dialysate flow and dialyzer mass transfer area coefficient to increase the clearance of protein‐bound solutes. J Am Soc Nephrol 2004 ; 15: 1927–1935.
3. 3 Stange J, Mitzner S. A carrier‐mediated transport of toxins in a hybrid membrane. Safety barrier between a patients blood and a bioartificial liver. Int J Artif Organs 1996 ; 19: 677–691.
4. 4 Sarnatskaya VV, Lindup WE, Niwa T, Ivanov AI, Yushko LA, Tjia J, et al. Effect of protein‐bound uraemic toxins on the thermodynamic characteristics of human albumin. Biochem Pharmacol 2002 ; 63: 1287–1296.
5. 5 Evenepoel P, Maes B, Wilmer A, Nevens F, Fevery J, Kuypers D, et al. Detoxifying capacity and kinetics of the molecular adsorbent recycling system. Contribution of the different inbuilt filters. Blood Purif 2003 ; 21: 244–252.
6. 6 Weiss JS, Gautam A, Lauff JJ, Sundberg MW, Jatlow P, Boyer JL, Seligson DN. The clinical importance of a protein‐bound fraction of serum bilirubin in patients with hyperbilirubinemia. N Engl J Med 1983 ; 309: 147–150.