Determination of quinolizidine alkaloids in Sophora tonkinensis by HPCE

Phytochemical Analysis

Volumn 16, Issue 4, 2005, Pages 257-263

  Ding, Pei Ian ^a   Yu, Yun Qiu ^a   Chen, Dao Feng ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

High performance capillary electrophoresis (HPCE); Leguminosae; Matrine; Oxymatrine; Quality assessment; Quinolizidine alkaloids; Sophora tonkinensis

Indexed keywords

CAPILLARY ELECTROPHORESIS; METABOLITES;

ALKALOID CONTENTS; HIGH PERFORMANCE CAPILLARY ELECTROPHORESIS; HIGH-PERFORMANCE CAPILLARY ELECTROPHORESIS; LEGUMINOSAE; MATRINE; OXYMATRINE; QUALITY ASSESSMENT; QUINOLIZIDINE ALKALOIDS; SIMPLE++; SOPHORA TONKINENSIS;

ALKALOIDS;

2 HYDROXYPROPYL BETA CYCLODEXTRIN; 2 PROPANOL; CYTISINE; LEHMANNINE; MATRINE; OXYMATRINE; OXYSOPHOCARPINE; PHOSPHATE BUFFERED SALINE; PLANT EXTRACT; QUINOLIZIDINE DERIVATIVE; SCOPOLAMINE BUTYL BROMIDE; SHAN DOU GEN; SOPHOCARPINE; SOPHORANOL; UNCLASSIFIED DRUG; WATER;

ARTICLE; CAPILLARY ELECTROPHORESIS; CHEMICAL ANALYSIS; CHINESE HERB; CONTROLLED STUDY; DRUG DETERMINATION; DRUG QUALITY; DRUG STRUCTURE; ELECTRIC POTENTIAL; NONHUMAN; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; SOPHORA; SOPHORA TONKINENSIS; STANDARD; TEMPERATURE;

FABACEAE; SOPHORA;

EID: 22144494165     PISSN: 09580344     EISSN: None     Source Type: Journal    
DOI: 10.1002/pca.829     Document Type: Article

References (19)

1. Cho CH, Chuang CY, Chen CF. 1986. Study of the antipyretic activity of matrine. A lupin alkaloid isolated from Sophora subprostrata. Planta Med 52: 343-345.
2. Ding PL, Chen DF. 2003. The pharmacological activities, clinical applications and side effects of the Chinese drug 'Shan-dou-gen' and its preparations. Zhongguo Lin Chuang Yao Xue Za Zhi 12: 315-318.
3. Ding Y, Tian RH, Takeshita T, Kinjo J, Nohara T. 1992. Four new oleanene glycosides from Sophorae Subprostratae Radix. Chem Pharm Bull 40: 1831-1834.
4. Dou JH, Li JS, Yan WM. 1989. Studies on the alkaloids of Radix Sophorae tonkinensis. Zhongguo Zhong Yao Za Zhi 14: 40-42.
5. Fang LQ, Guo JX. 1992. Research progress on Chinese drug 'Shan-dou-gen'. Tian Ran Chan Wu Yan Jiu Yu Kai Fa 4: 94-106.
6. Fang LQ, Guo JX, Zheng LX. 1992. Quality evaluation of the Chinese traditional drugs 'Shan-dou-gen' and 'Beidou-gen'. J Shanghai Med Univ 19: 124-128.
7. Kinghorn AD, Balandrin ME 1984. Quinolizidine alkaloids of the Leguminosae: structural types, analysis, chemotaxonomy and biological activities. In Alkaloids: Chemical and Biological Perspectives, Vol 2, Pelletier S-W (ed.). Wiley: New York; 105-148.
8. Komatsu M, Tomimori T, Hatayama K, Makiguchi Y, Mikuriya N. 1970. Studies on the constituents of Sophora species. Constituents of Sophora subprostrata Chun et T. Chen. (1). Isolation and structure of new flavonoids, sophoradin and sophoranone. Chem Pharm Bull 18: 602-607.
9. Ku YR, Chang LY, Lin JH, Ho LK. 2002. Determination of matrine and oxymatrine in Sophora subprostrata by CE. J Pharm Biomed Anal 28: 1005-1010.
10. Kyogoku K, Hatayama K, Yokomori S, Shio M, Komatsu M. 1973. Studies on the constituents of Sophora species. Constituents of the root of Sophora subprostrata Chun et T. Chen. (4). Chem Pharm Bull 21: 1192-1197.
11. Ma CH, Cao TH. 2000. Determination of alkaloids in Sophora tonkinensis Gapnep. by HPLC. Yao Wu Fen Xi Za Zhi 20: 408-410.
12. Shirataki Y, Yokoe I, Komatsu M. 1986. Two new flavone glycosides from the roots of Sophora subprostrata. J Nat Prod 49: 645-649.
13. Song JZ, Xu HX, Tian SJ, But Paul PH. 1999. Determination of quinolizidine alkaloids in traditional Chinese herbal drugs by non-aqueous capillary electrophoresis. J Chromatogr A 857: 303-311.
14. State Pharmacopoeia Commission of PRC. 2000. Pharmacopoeia of the People's Republic of China, Vol 1. Chemical Industry Press: Beijing; 21.
15. Takeshita T, Yokoyama K, Ding Y, Kinjo J, Nohara T. 1991. Four new and twelve known sapogenols from Sophorae Subprostratae Radix. Chem Pharm Bull 39: 1908-1910.
16. Xiao P, Li JS, Kubo H, Saito K, Murakoshi I, Ohmiya S. 1996. (-)-14β-Hydroxymatrine, a new lupine alkaloid from the roots of Sophora tonkinensis. Chem Pharm Bull 44: 1951-1953.
17. Xiao P, Kubo H, Komiya H, Higashiyama K, Yan YN, Li JS, Ohmiya S. 1999. (-)-14β-Acetoxymatrine and (+)-14α-acetoxymatrine, two new matrine-type lupin alkaloids from the leaves of Sophora tonkinensis. Chem Pharm Bull 47: 448-450.
18. Yamazaki M. 2000. The pharmacological studies on matrine and oxymatrine. Yakugaku Zasshi 120: 1025-1033.
19. Zhang LZ, Li JS, Houghton PJ, Jackson S, Twentyman PR. 1997. Alkaloids in Sophora alopecuroides seed and relevant tests for activity. Zhongguo Zhong Yao Za Zhi 22: 740-743.