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Volumn 66, Issue 3, 2005, Pages 203-211

Limits on recovery in the corticospinal tract of the rat: Partial lesions impair skilled reaching and the topographic representation of the forelimb in motor cortex

Author keywords

Cortical stimulation and movement; Motor maps; Pyramidal tract; Rat pyramidal tract; Recovery from pyramidal tract lesion; Skilled reaching; Skilled reaching and pyramidal tract

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARM MOVEMENT; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN MAPPING; BRAIN REGION; CONTROLLED STUDY; CONVALESCENCE; ELECTROPHYSIOLOGY; EVOKED MUSCLE RESPONSE; FEMALE; FORELIMB; MEDULLA OBLONGATA; MOTOR CORTEX; MOTOR PERFORMANCE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL SIGN; PYRAMIDAL TRACT; RAT; TASK PERFORMANCE; TOPOGRAPHY;

EID: 22144493873     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2005.04.013     Document Type: Article
Times cited : (45)

References (64)
  • 2
    • 0036714204 scopus 로고    scopus 로고
    • An index of topographic normality in rat somatosensory cortex: Application to a sciatic nerve crush model
    • S. Barbay, E.K. Peden, G. Falchook, and R.J. Nudo An index of topographic normality in rat somatosensory cortex: application to a sciatic nerve crush model J. Neurophsiol. 88 2002 1339 1351
    • (2002) J. Neurophsiol. , vol.88 , pp. 1339-1351
    • Barbay, S.1    Peden, E.K.2    Falchook, G.3    Nudo, R.J.4
  • 3
    • 0002412296 scopus 로고
    • Study of localization in the corticospinal tracts of monkey and rat
    • J.W. Barnard, and C.M. Woolsey Study of localization in the corticospinal tracts of monkey and rat J. Comp. Neurol. 105 1956 25 50
    • (1956) J. Comp. Neurol. , vol.105 , pp. 25-50
    • Barnard, J.W.1    Woolsey, C.M.2
  • 4
    • 0035821432 scopus 로고    scopus 로고
    • Neuronal plasticity and formation of new synaptic contacts follow pyramidal lesions and neutralization of Nogo-A: A light and electron microscopic study in the pontine nuclei of adult rats
    • S. Blochlinger, O. Weinmann, M.E. Schwab, and M. Thallmair Neuronal plasticity and formation of new synaptic contacts follow pyramidal lesions and neutralization of Nogo-A: a light and electron microscopic study in the pontine nuclei of adult rats J. Comp. Neurol. 7 2001 426 436
    • (2001) J. Comp. Neurol. , vol.7 , pp. 426-436
    • Blochlinger, S.1    Weinmann, O.2    Schwab, M.E.3    Thallmair, M.4
  • 5
    • 0025934966 scopus 로고
    • Cortical microstimulation thresholds adjacent to sensorimotor cortex injury
    • M.G. Boyeson, D.M. Feeney, and W.G. Dail Cortical microstimulation thresholds adjacent to sensorimotor cortex injury J. Neurotrauma 8 1991 205 217
    • (1991) J. Neurotrauma , vol.8 , pp. 205-217
    • Boyeson, M.G.1    Feeney, D.M.2    Dail, W.G.3
  • 6
    • 0015240311 scopus 로고
    • Projections and termination of the corticospinal tract in rodents
    • L.T.J. Brown Projections and termination of the corticospinal tract in rodents Exp. Brain Res. 13 1971 432 450
    • (1971) Exp. Brain Res. , vol.13 , pp. 432-450
    • Brown, L.T.J.1
  • 8
    • 0029144459 scopus 로고
    • Functional recovery of forelimb response capacity after forelimb primary motor cortex damage in the rat is due to the reorganization of adjacent areas of cortex
    • M.A. Castro-Alamancos, and J. Borrel Functional recovery of forelimb response capacity after forelimb primary motor cortex damage in the rat is due to the reorganization of adjacent areas of cortex Neuroscience 68 1995 793 805
    • (1995) Neuroscience , vol.68 , pp. 793-805
    • Castro-Alamancos, M.A.1    Borrel, J.2
  • 9
    • 0022002399 scopus 로고
    • Comparable patterns of muscle facilitation evoked by individual corticomotoneuronal (CM) cells and by single intracortical microstimuli in primates: Evidence for functional groups of CM cells
    • P.D. Cheney, and E.E. Fetz Comparable patterns of muscle facilitation evoked by individual corticomotoneuronal (CM) cells and by single intracortical microstimuli in primates: evidence for functional groups of CM cells J. Neurophysiol. 53 1985 786 804
    • (1985) J. Neurophysiol. , vol.53 , pp. 786-804
    • Cheney, P.D.1    Fetz, E.E.2
  • 10
    • 0022701620 scopus 로고
    • Somatotopic analysis of fiber and terminal distribution in the primate corticospinal pathway
    • N.A. Dawnay, and P. Glees Somatotopic analysis of fiber and terminal distribution in the primate corticospinal pathway Brain Res. 391 1986 115 123
    • (1986) Brain Res. , vol.391 , pp. 115-123
    • Dawnay, N.A.1    Glees, P.2
  • 11
    • 0019467079 scopus 로고
    • A collateral pathway tot he neostritum from corticofugal neurons of the rat sensory-motor cortex: An intracellular HRP study
    • J.P. Donoghue, and S.T. Kitai A collateral pathway tot he neostritum from corticofugal neurons of the rat sensory-motor cortex: an intracellular HRP study J. Comp. Neurol. 201 1981 1 13
    • (1981) J. Comp. Neurol. , vol.201 , pp. 1-13
    • Donoghue, J.P.1    Kitai, S.T.2
  • 12
    • 0020422484 scopus 로고
    • The motor cortex of the rat: Cytoarchitecture and microstimulation mapping
    • J.P. Donoghue, and S.P. Wise The motor cortex of the rat: cytoarchitecture and microstimulation mapping J. Comp. Neurol. 212 1982 76 88
    • (1982) J. Comp. Neurol. , vol.212 , pp. 76-88
    • Donoghue, J.P.1    Wise, S.P.2
  • 14
    • 0022362614 scopus 로고
    • Labeled corticospinal neurons one year after spinal cord transection
    • E.R. Feringa, and H.L. Vahlsing Labeled corticospinal neurons one year after spinal cord transection Neurosci. Lett. 58 1985 283 286
    • (1985) Neurosci. Lett. , vol.58 , pp. 283-286
    • Feringa, E.R.1    Vahlsing, H.L.2
  • 15
    • 0031656436 scopus 로고    scopus 로고
    • Recovery of motor function after focal cortical injury in primates: Compensatory movement patterns used during rehabilitative training
    • K.M. Friel, and R.J. Nudo Recovery of motor function after focal cortical injury in primates: compensatory movement patterns used during rehabilitative training Somatosens. Mot. Res. 15 1998 173 189
    • (1998) Somatosens. Mot. Res. , vol.15 , pp. 173-189
    • Friel, K.M.1    Nudo, R.J.2
  • 16
    • 0033600472 scopus 로고    scopus 로고
    • Quantitative analyses of neurons projecting to primary motor cortex zones controlling limb movements in the rat
    • X. Gu, W.A. Staines, and P.A. Fortier Quantitative analyses of neurons projecting to primary motor cortex zones controlling limb movements in the rat Brain Res. 835 1999 175 187
    • (1999) Brain Res. , vol.835 , pp. 175-187
    • Gu, X.1    Staines, W.A.2    Fortier, P.A.3
  • 17
    • 0015958984 scopus 로고
    • Organization of motor and somatosensory neocortex in the albino rat
    • R.D. Hall, and E.P. Lindholm Organization of motor and somatosensory neocortex in the albino rat Brain Res. 66 1974 23 38
    • (1974) Brain Res. , vol.66 , pp. 23-38
    • Hall, R.D.1    Lindholm, E.P.2
  • 18
    • 0038649642 scopus 로고    scopus 로고
    • Primary cortical motor neurons undergo apoptosis after axotomizing spinal cord injury
    • B.C. Hains, J.A. Black, and S.G. Waxman Primary cortical motor neurons undergo apoptosis after axotomizing spinal cord injury J. Comp. Neurol. 462 2003 328 341
    • (2003) J. Comp. Neurol. , vol.462 , pp. 328-341
    • Hains, B.C.1    Black, J.A.2    Waxman, S.G.3
  • 19
    • 0016736383 scopus 로고
    • The mode of activation of pyramidal tract cells by intracortical stimuli
    • E. Jankowska, Y. Padel, and R. Tanaka The mode of activation of pyramidal tract cells by intracortical stimuli J. Physiol. 249 1975 617 636
    • (1975) J. Physiol. , vol.249 , pp. 617-636
    • Jankowska, E.1    Padel, Y.2    Tanaka, R.3
  • 20
    • 0016798780 scopus 로고
    • Motor performance following unilateral pyramidal tract lesions in the hamster
    • K. Kalil, and G.E. Schneider Motor performance following unilateral pyramidal tract lesions in the hamster Brain Res. 100 1975 170 174
    • (1975) Brain Res. , vol.100 , pp. 170-174
    • Kalil, K.1    Schneider, G.E.2
  • 21
    • 0032440820 scopus 로고    scopus 로고
    • Functional reorganization of the rat motor cortex following motor skill learning
    • J.A. Kleim, S. Barbay, and R.J. Nudo Functional reorganization of the rat motor cortex following motor skill learning J. Neurophys. 80 1998 3321 3325
    • (1998) J. Neurophys. , vol.80 , pp. 3321-3325
    • Kleim, J.A.1    Barbay, S.2    Nudo, R.J.3
  • 23
    • 0021688312 scopus 로고
    • Morphological and electrophysiological characteristics of pyramidal tract neurons in the rat
    • P. Landry, C.J. Wilson, and S.T. Kitai Morphological and electrophysiological characteristics of pyramidal tract neurons in the rat Exp. Brain Res. 57 1984 177 190
    • (1984) Exp. Brain Res. , vol.57 , pp. 177-190
    • Landry, P.1    Wilson, C.J.2    Kitai, S.T.3
  • 24
    • 0041315446 scopus 로고    scopus 로고
    • Differential impairment of individuated finger movements in humans after damage to the motor cortex or the corticospinal tract
    • C.E. Lang, and M.H. Schieber Differential impairment of individuated finger movements in humans after damage to the motor cortex or the corticospinal tract J. Neurophysiol. 90 2003 1160 1170
    • (2003) J. Neurophysiol. , vol.90 , pp. 1160-1170
    • Lang, C.E.1    Schieber, M.H.2
  • 25
    • 0015233986 scopus 로고
    • A kinesthetic deficit after partial transection of a pyramidal tract in monkeys
    • A.M. Laursen A kinesthetic deficit after partial transection of a pyramidal tract in monkeys Brain Res. 31 1971 263 274
    • (1971) Brain Res. , vol.31 , pp. 263-274
    • Laursen, A.M.1
  • 26
    • 0017153824 scopus 로고
    • The development of motor control in the rhesus monkey: Evidence concerning the role of corticomoneuronal connections
    • D.G. Lawrence, and D.A. Hopkins The development of motor control in the rhesus monkey: Evidence concerning the role of corticomoneuronal connections Brain 99 1976 235 254
    • (1976) Brain , vol.99 , pp. 235-254
    • Lawrence, D.G.1    Hopkins, D.A.2
  • 27
    • 0014259748 scopus 로고
    • The functional organization of the motor system in the monkey, I. Effects of bilateral pyramidal lesions
    • D.G. Lawrence, and G.J.M. Kuypers The functional organization of the motor system in the monkey, I. Effects of bilateral pyramidal lesions Brain 91 1968 1 14
    • (1968) Brain , vol.91 , pp. 1-14
    • Lawrence, D.G.1    Kuypers, G.J.M.2
  • 28
    • 0029557940 scopus 로고
    • Mechanisms underlying functional recovery following stroke
    • R.G. Lee, and P. van Donkellar Mechanisms underlying functional recovery following stroke Can. J. Neurol. Sci. 22 1995 257 263
    • (1995) Can. J. Neurol. Sci. , vol.22 , pp. 257-263
    • Lee, R.G.1    Van Donkellar, P.2
  • 29
    • 0022378935 scopus 로고
    • A detailed morphometrical analysis of the pyramidal tract of the rat
    • L.P. Leenen, J. Meek, P.R. Posthuma, and R.A. Nieuwenhuys A detailed morphometrical analysis of the pyramidal tract of the rat Brain Res. 359 1985 65 80
    • (1985) Brain Res. , vol.359 , pp. 65-80
    • Leenen, L.P.1    Meek, J.2    Posthuma, P.R.3    Nieuwenhuys, R.A.4
  • 30
    • 0023187389 scopus 로고
    • The effects upon the activity of hand and forearm muscles of intracortical stimulation in the vicinity of corticomotor neurons in the conscious monkey
    • R. Lemon, R. Muir, and G. Mantel The effects upon the activity of hand and forearm muscles of intracortical stimulation in the vicinity of corticomotor neurons in the conscious monkey Exp. Brain Res. 66 1987 621 637
    • (1987) Exp. Brain Res. , vol.66 , pp. 621-637
    • Lemon, R.1    Muir, R.2    Mantel, G.3
  • 31
    • 0346340052 scopus 로고    scopus 로고
    • Clinicotopographical correlation of corticospinal tract stroke: A color-coded diffusion tensor imaging study
    • C. Lie, J.G. Hirsch, C. Rossmanith, and M.G. Hennerici Clinicotopographical correlation of corticospinal tract stroke: a color-coded diffusion tensor imaging study Stroke 35 2004 86 92
    • (2004) Stroke , vol.35 , pp. 86-92
    • Lie, C.1    Hirsch, J.G.2    Rossmanith, C.3    Hennerici, M.G.4
  • 32
    • 0025339830 scopus 로고
    • Cell death of corticospinal neurons is induced by axotomy before but not after innervation of spinal targets
    • M. Merline, and K. Kalil Cell death of corticospinal neurons is induced by axotomy before but not after innervation of spinal targets J. Comp. Neurol. 296 1990 506 516
    • (1990) J. Comp. Neurol. , vol.296 , pp. 506-516
    • Merline, M.1    Kalil, K.2
  • 33
    • 0032212382 scopus 로고    scopus 로고
    • The effects of unilateral pyramidal tract section on hind limb motor performance in the rat
    • G.A. Metz, V. Dietz, M.E. Schwab, and H. van de Meent The effects of unilateral pyramidal tract section on hind limb motor performance in the rat Behav. Brain Res. 96 1998 37 46
    • (1998) Behav. Brain Res. , vol.96 , pp. 37-46
    • Metz, G.A.1    Dietz, V.2    Schwab, M.E.3    Van De Meent, H.4
  • 34
    • 0023258149 scopus 로고
    • The origin of corticospinal projection neurons in rat
    • M.W. Miller The origin of corticospinal projection neurons in rat Exp. Brain Res. 67 1987 339 351
    • (1987) Exp. Brain Res. , vol.67 , pp. 339-351
    • Miller, M.W.1
  • 35
    • 0032880887 scopus 로고    scopus 로고
    • Complete locomotor recovery following corticospinal tract lesions: Measurement of ground reaction forces during overground locomotion in rats
    • G.D. Muir, and I.Q. Whishaw Complete locomotor recovery following corticospinal tract lesions: measurement of ground reaction forces during overground locomotion in rats Behav. Brain Res. 103 1999 45 53
    • (1999) Behav. Brain Res. , vol.103 , pp. 45-53
    • Muir, G.D.1    Whishaw, I.Q.2
  • 36
    • 0020042892 scopus 로고
    • A second forelimb motor area exists in rat frontal cortex
    • E.J. Neafsey, and C. Sievert A second forelimb motor area exists in rat frontal cortex Brain Res. 232 1982 151 156
    • (1982) Brain Res. , vol.232 , pp. 151-156
    • Neafsey, E.J.1    Sievert, C.2
  • 38
    • 0025314073 scopus 로고
    • Descending pathways to the spinal cord, III: Sites of origin of the corticospinal tract
    • R.J. Nudo, and R.B. Masterton Descending pathways to the spinal cord, III: Sites of origin of the corticospinal tract J. Comp. Neurol. 296 1990 559 583
    • (1990) J. Comp. Neurol. , vol.296 , pp. 559-583
    • Nudo, R.J.1    Masterton, R.B.2
  • 39
    • 0025315197 scopus 로고
    • Descending pathways to the spinal cord, IV: Some factors related to the amount of cortex devoted to the corticospinal tract
    • R.J. Nudo, and R.B. Masterton Descending pathways to the spinal cord, IV: some factors related to the amount of cortex devoted to the corticospinal tract J. Comp. Neurol. 296 1990 584 597
    • (1990) J. Comp. Neurol. , vol.296 , pp. 584-597
    • Nudo, R.J.1    Masterton, R.B.2
  • 40
    • 0030033443 scopus 로고    scopus 로고
    • Use-dependent alterations of movement representations in primary motor cortex of adult squirrel monkeys
    • R.J. Nudo, G.W. Milliken, W.M. Jenkins, and M.M. Merzenich Use-dependent alterations of movement representations in primary motor cortex of adult squirrel monkeys J. Neurosci. 16 1996 785 807
    • (1996) J. Neurosci. , vol.16 , pp. 785-807
    • Nudo, R.J.1    Milliken, G.W.2    Jenkins, W.M.3    Merzenich, M.M.4
  • 41
    • 0036436365 scopus 로고    scopus 로고
    • Reorganization of descending motor tracts in the rat spinal cord
    • O. Raineteau, K. Fouad, F.M. Bareyre, and M.E. Schwab Reorganization of descending motor tracts in the rat spinal cord Eur. J. Neurosci. 16 2002 1761 1771
    • (2002) Eur. J. Neurosci. , vol.16 , pp. 1761-1771
    • Raineteau, O.1    Fouad, K.2    Bareyre, F.M.3    Schwab, M.E.4
  • 42
    • 0035860649 scopus 로고    scopus 로고
    • Sensitivity of cortical movement representations to motor experience: Evidence that skill learning but not strength training induces cortical organization
    • M.S. Remple, R.M. Bruneau, P.M. VandenBerg, C. Goertzen, and J.A. Kleim Sensitivity of cortical movement representations to motor experience: evidence that skill learning but not strength training induces cortical organization Behav. Brain Res. 123 2001 133 141
    • (2001) Behav. Brain Res. , vol.123 , pp. 133-141
    • Remple, M.S.1    Bruneau, R.M.2    Vandenberg, P.M.3    Goertzen, C.4    Kleim, J.A.5
  • 43
    • 0027358815 scopus 로고
    • Comparison of the connectional properties of the two forelimb areas of the rat sensorimotor cortex: Support for the presence of a premotor or supplementary motor cortical area
    • E.M. Rouiller, V. Moret, and F. Liang Comparison of the connectional properties of the two forelimb areas of the rat sensorimotor cortex: support for the presence of a premotor or supplementary motor cortical area Somatosens. Mot. Res. 10 1993 269 289
    • (1993) Somatosens. Mot. Res. , vol.10 , pp. 269-289
    • Rouiller, E.M.1    Moret, V.2    Liang, F.3
  • 44
    • 0035655477 scopus 로고    scopus 로고
    • Constraints on somatotopic organization in the primary motor cortex
    • M.H. Schieber Constraints on somatotopic organization in the primary motor cortex J. Neurophysiol. 86 2001 2125 2143
    • (2001) J. Neurophysiol. , vol.86 , pp. 2125-2143
    • Schieber, M.H.1
  • 45
    • 3142768943 scopus 로고    scopus 로고
    • Progressive plastic changes in the hand representation of the primary motor cortex parallel incomplete recovery from a unilateral section of the corticospinal tract at cervical level in monkeys
    • E. Schmidlin, T. Wannier, J. Bloch, and E.M. Rouiller Progressive plastic changes in the hand representation of the primary motor cortex parallel incomplete recovery from a unilateral section of the corticospinal tract at cervical level in monkeys Brain Res. 1017 2004 172 183
    • (2004) Brain Res. , vol.1017 , pp. 172-183
    • Schmidlin, E.1    Wannier, T.2    Bloch, J.3    Rouiller, E.M.4
  • 46
    • 0025259466 scopus 로고
    • A rapid, sensitive histochemical stain for myelin in frozen brain section
    • L.C. Schmued A rapid, sensitive histochemical stain for myelin in frozen brain section J. Histochem. Cytochem. 38 1990 717 720
    • (1990) J. Histochem. Cytochem. , vol.38 , pp. 717-720
    • Schmued, L.C.1
  • 47
    • 0014329064 scopus 로고
    • Excitation of pyramidal tract cells by intracortical microstimulation: Effective extent of stimulating current
    • S.D. Stoney Jr., W.D. Thompson, and H. Asanuma Excitation of pyramidal tract cells by intracortical microstimulation: effective extent of stimulating current J. Neurophysiol. 31 1968 659 666
    • (1968) J. Neurophysiol. , vol.31 , pp. 659-666
    • Stoney Jr., S.D.1    Thompson, W.D.2    Asanuma, H.3
  • 48
    • 0029042577 scopus 로고
    • Anatomy, development and lesion-induced plasticity of rodent corticospinal tract
    • T. Terashima Anatomy, development and lesion-induced plasticity of rodent corticospinal tract Neurosci. Res. 22 1995 139 161
    • (1995) Neurosci. Res. , vol.22 , pp. 139-161
    • Terashima, T.1
  • 49
    • 0011258644 scopus 로고    scopus 로고
    • Expansion of movement representations within rat motor cortex following kindling
    • G.C. Teskey, M. Monfils, P.M. VandenBerg, and J.A. Kleim Expansion of movement representations within rat motor cortex following kindling Cereb. Cortex 12 2001 98 105
    • (2001) Cereb. Cortex , vol.12 , pp. 98-105
    • Teskey, G.C.1    Monfils, M.2    Vandenberg, P.M.3    Kleim, J.A.4
  • 50
    • 0032082502 scopus 로고    scopus 로고
    • Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions
    • M. Thallmair, G.A. Metz, W.R. Z'Graggen, O. Raineteau, G.L. Kartje, and M.E. Schwab Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions Nat. Neurosci. 1 1998 124 131
    • (1998) Nat. Neurosci. , vol.1 , pp. 124-131
    • Thallmair, M.1    Metz, G.A.2    Z'Graggen, W.R.3    Raineteau, O.4    Kartje, G.L.5    Schwab, M.E.6
  • 51
    • 0030052490 scopus 로고    scopus 로고
    • Structural and functional alterations in rat corticospinal neurons after axotomy
    • G.F. Tseng, and D.A. Prince Structural and functional alterations in rat corticospinal neurons after axotomy J. Neurophysiol. 75 1996 248 267
    • (1996) J. Neurophysiol. , vol.75 , pp. 248-267
    • Tseng, G.F.1    Prince, D.A.2
  • 52
    • 0019479758 scopus 로고
    • Synaptic plasticity in the mammalian central nervous system
    • N. Tsukahara synaptic plasticity in the mammalian central nervous system Annu. Rev. Neurosci. 4 1991 351 379
    • (1991) Annu. Rev. Neurosci. , vol.4 , pp. 351-379
    • Tsukahara, N.1
  • 53
    • 0037403572 scopus 로고    scopus 로고
    • NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection
    • M.H. Tuszynski, R. Grill, L.L. Jones, A. Brant, A. Blesch, K. Low, S. Lacroix, and P. Lu NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection Exp. Neurol. 181 2003 47 56
    • (2003) Exp. Neurol. , vol.181 , pp. 47-56
    • Tuszynski, M.H.1    Grill, R.2    Jones, L.L.3    Brant, A.4    Blesch, A.5    Low, K.6    Lacroix, S.7    Lu, P.8
  • 54
    • 0035853114 scopus 로고    scopus 로고
    • Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury
    • N. Weidner, A. Ner, N. Salimi, and T.M. Tuszynski Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury Proc. Natl. Acad. Sci. 13 2001 3513 3518
    • (2001) Proc. Natl. Acad. Sci. , vol.13 , pp. 3513-3518
    • Weidner, N.1    Ner, A.2    Salimi, N.3    Tuszynski, T.M.4
  • 55
    • 0033980568 scopus 로고    scopus 로고
    • Loss of the innate cortical engram for action patterns used in skilled reaching and the development of behavioral compensation following motor cortex lesions in the rat
    • I.Q. Whishaw Loss of the innate cortical engram for action patterns used in skilled reaching and the development of behavioral compensation following motor cortex lesions in the rat Neuropharmacology 39 2000 788 805
    • (2000) Neuropharmacology , vol.39 , pp. 788-805
    • Whishaw, I.Q.1
  • 56
    • 0037151286 scopus 로고    scopus 로고
    • Assessment of the ipsilateral pyramidal tract contribution to skilled movement in the rat: Absence of ipsilateral impairments in limb spasticity, placing, preference, and quantitative and qualitative performance in skilled reaching tasks vs enduring contralateral deficits
    • I.Q. Whishaw, and G.A. Metz Assessment of the ipsilateral pyramidal tract contribution to skilled movement in the rat: absence of ipsilateral impairments in limb spasticity, placing, preference, and quantitative and qualitative performance in skilled reaching tasks vs enduring contralateral deficits Behav. Brain Res. 134 2002 323 326
    • (2002) Behav. Brain Res. , vol.134 , pp. 323-326
    • Whishaw, I.Q.1    Metz, G.A.2
  • 57
    • 0023032147 scopus 로고
    • The contributions of motor cortex, nigrostriatal dopamine and caudate-putamen to skilled forelimb use in the rat
    • I.Q. Whishaw, W.T. O'Connor, and S.B. Dunnett The contributions of motor cortex, nigrostriatal dopamine and caudate-putamen to skilled forelimb use in the rat Brain 109 1986 805 843
    • (1986) Brain , vol.109 , pp. 805-843
    • Whishaw, I.Q.1    O'Connor, W.T.2    Dunnett, S.B.3
  • 58
    • 0025201875 scopus 로고
    • The structure of skilled forelimb reaching in the rat: Proximally driven movement with a single rotatory component
    • I.Q. Whishaw, and S.M. Pellis The structure of skilled forelimb reaching in the rat: proximally driven movement with a single rotatory component Behav. Brain Res. 41 1990 49 59
    • (1990) Behav. Brain Res. , vol.41 , pp. 49-59
    • Whishaw, I.Q.1    Pellis, S.M.2
  • 59
    • 0027219846 scopus 로고
    • Proximal and distal impairments in rat forelimb use in reaching follow unilateral pyramidal tract lesions
    • I.Q. Whishaw, S.M. Pellis, B. Gorny, B. Kolb, and W. Tetzlaff Proximal and distal impairments in rat forelimb use in reaching follow unilateral pyramidal tract lesions Behav. Brain Res. 56 1993 59 67
    • (1993) Behav. Brain Res. , vol.56 , pp. 59-67
    • Whishaw, I.Q.1    Pellis, S.M.2    Gorny, B.3    Kolb, B.4    Tetzlaff, W.5
  • 60
    • 1542465818 scopus 로고    scopus 로고
    • Complete and partial lesions of the pyramidal tract in the rat affect qualitative measures of skilled movements: Impairment in fixations as a model for clumsy behavior
    • I.Q. Whishaw, D.M. Piecharka, and F.R. Drever Complete and partial lesions of the pyramidal tract in the rat affect qualitative measures of skilled movements: impairment in fixations as a model for clumsy behavior Neural Plast. 10 2003 77 92
    • (2003) Neural Plast. , vol.10 , pp. 77-92
    • Whishaw, I.Q.1    Piecharka, D.M.2    Drever, F.R.3
  • 61
    • 0018754604 scopus 로고
    • Somatotopic organization of corticospinal and corticotrigeminal neurons in the rat
    • S.P. Wise, E.A. Murray, and J.D. Coulter Somatotopic organization of corticospinal and corticotrigeminal neurons in the rat Neuroscience 4 1979 65 78
    • (1979) Neuroscience , vol.4 , pp. 65-78
    • Wise, S.P.1    Murray, E.A.2    Coulter, J.D.3
  • 62
    • 0037392912 scopus 로고    scopus 로고
    • An electron microscopic examination of the corticospinal projection to the cervical spinal cord in the rat: Lack of evidence of cortico-motoneuronal synapses
    • W.H. Yang, and RN. Lemon An electron microscopic examination of the corticospinal projection to the cervical spinal cord in the rat: lack of evidence of cortico-motoneuronal synapses Exp. Brain Res. 149 2003 458 469
    • (2003) Exp. Brain Res. , vol.149 , pp. 458-469
    • Yang, W.H.1    Lemon, R.N.2
  • 63
    • 0034281370 scopus 로고    scopus 로고
    • Compensatory sprouting and impulse rerouting after unilateral pyramidal tract lesion in neonatal rats
    • W.J. Z'Graggen, K. Fouad, O. Raineteau, G.A. Metz, M.E. Schwab, and G.L. Kartje Compensatory sprouting and impulse rerouting after unilateral pyramidal tract lesion in neonatal rats J. Neurosci. 20 2000 6561 6569
    • (2000) J. Neurosci. , vol.20 , pp. 6561-6569
    • Z'Graggen, W.J.1    Fouad, K.2    Raineteau, O.3    Metz, G.A.4    Schwab, M.E.5    Kartje, G.L.6
  • 64
    • 0032526742 scopus 로고    scopus 로고
    • Functional recovery and enhanced corticofugal plasticity after unilateral pyramidal tract lesion and blockade of myelin-associated neurite growth inhibitors in adult rats
    • W.J. Z'Graggen, G.A. Metz, G.L. Kartje, M. Thallmair, and M.E. Schwab Functional recovery and enhanced corticofugal plasticity after unilateral pyramidal tract lesion and blockade of myelin-associated neurite growth inhibitors in adult rats J. Neurosci. 18 1998 4744 4757
    • (1998) J. Neurosci. , vol.18 , pp. 4744-4757
    • Z'Graggen, W.J.1    Metz, G.A.2    Kartje, G.L.3    Thallmair, M.4    Schwab, M.E.5


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