Expression of bcl-2 oncogene in gastric precancerous lesions and its correlation with syndromes on traditional Chinese medicine

World Journal of Gastroenterology

Volumn 11, Issue 21, 2005, Pages 3293-3296

  Hu, Ling ^a   Lao, Shao Xian ^a   Tang, Chun Zhi ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Oncogene bcl 2; Precancerous condition pathology; Stomach neoplasm genetics; Stomach neoplasm therapy of TCM; Syndrome of TCM

Indexed keywords

MESSENGER RNA; PROTEIN BCL 2;

ADULT; AGED; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; GASTROSCOPY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MAJOR CLINICAL STUDY; ONCOGENE; PRECANCER; PROTEIN EXPRESSION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STOMACH CANCER; TUMOR DIFFERENTIATION;

EID: 22144491183     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i21.3293     Document Type: Article

References (33)

1. You WC, Li JY, Blot WJ, Chang YS, Jin ML, Gail MH, Zhang L, Liu WD, Ma JL, Hu YR, Mark SD, Correa P, Fraumeni JF Jr, Xu GW. Evolution of precancerous lesions in a rural Chinese population at high risk of gastric cancer. Int J Cancer 1999; 83: 615-619
2. Misdraji J, Lauwers GY. Gastric epithelial dysplasia. Semin Diagn Pathol 2002; 19: 20-30
3. Cesar AC, Silva AE, Tajara EH. Genetics and environmental factors in gastric carcinogenesis. Arq Gastroenterol 2002; 39: 253-259
4. Chen X, Wang MW, You WD. Relationship between Helicobacter pylori infection and proliferation and apoptosis of gastric epithelial dysplasia cell. Aizheng 2003; 22: 244-247
5. van Grieken NC, Meijer GA, zur Hausen A, Meuwissen SG, Baak JP, Kuipers EJ. Increased apoptosis in gastric mucosa adjacent to intestinal metaplasia. J Clin Pathol 2003; 56: 358-361
6. Correa P, Miller MJ. Carcinogenesis, apoptosis and cell proliferation. Br Med Bull 1998; 54: 151-162
7. Xu A, Li S, Liu J. Correlation between apoptosis and proliferation in gastric pre-carcinoma. Zhonghua Yixue Zazhi 1999; 79: 185-186
8. Pan CJ, Zhong P, Huang XR, Liu KY, Wang SX. Study on the correlation between proliferation and apoptosis in atrophy and intestinal metaplasia of gastric mucosa. Shijie Huaren Xiaohua Zazhi 2000; 8: 143-146
9. Pan CJ, Liu KY. Proliferation/apoptosis and expression of P53 and Bcl-2 in gastric carcinoma. Shijie Huaren Xiaohua Zazhi 2003; 11: 526-530
10. Mong H, Liu LN, Lv S. Expression of relating genes protein of proliferation and apoptosis in Gastric cancer and its precancerous lesion of gastric mucosa. Shijie Huaren Xiaohua Zazhi 2004; 12: 494-496
11. Zhong WR, Huang YX, Cui JP. Clinical study on modified sijunzi decoction in treating intestinal metaplasia of gastric mucosa. Zhongguo Zhongxiyi Jiehe Zazhi 1997; 17: 462-464
12. Lao SHX, Xu XM, Zhou FSH, Yu SHY, Jia JG, Zheng YX, Huang ZHX, Guo SCH, Bian ZHX. The analysis of therapeutic effect in precancerous lesion of gastric cancer by WeiYanXiao. Zhongyao Xinyao Yu Linchuang Yaoli 1997; 8: 72-75
13. Hu L, Lao SX, Zhou FS. The strategy Of therapeutic study on precancerous lesion of gastric cancer by traditional Chinese medicine. Shijie Huaren Xiaohua Zazhi 2000; 8(Suppl 8): 3
14. Hu L, Lao SX. P21 and P53 protein expression in gastric precancerous lesions and regulating effect of Weiyanxiao. Huaren Xiaohua Zazhi 1998; 6: 873-874
15. Hu L, Lao SX. Expression of relative genes in precancerous lesion of gastric cancer and the regulating effect of WeiYanXiao on it. Zhongguo Zhongxiyi Jiehe Piwei Zazhi 1999; 7: 91-92
16. Hu L, Lao SX, Zhou FS, Tang CZ. Regulating effects of WeiYanXiao in target gene expression in gases with precancerous lesion of gastric carcinoma. Zhejiang Zhongxiyi Jiehe Zazhi 2001; 11: 334-336
17. Hu L, Lao SX. Effect of Epidermal Growth Factor Receptor expression in precancerous lesions of gastric cancer by WeiYanXiao. Zhongguo Zhongxiyi Jiehe Xiaohua Zazhi 2003; 11: 331-333
18. Hu L. Preliminary exploration of the relationship between apoptosis and gastric carcinoma and precancerosis. CJIM 1999; 5: 142-145
19. Sun SH, Sun BY, Zhi HL, Xu XF, Sun DZH. Poptosis and expression of its regulating gene in gastric carcinoma and its precancerous lesions. Zhongguo Bingli Shengli Zazhi 2002; 18: 395-397
20. Jorge O, Cuello Carrion FD, Jorge A, Ciocca DR. Helicobacter pylori infection affects the expression of PCNA, p53, c-erbB-2 and Bcl-2 in the human gastric mucosa. Rev Esp Enferm Dig 2003; 95: 97-104
21. Lu XG, Feng BA, Zhan LB, Yu ZH. D-limonene induces apoptosis of gastric cancer cells. Zhonghua Zhongliu Zazhi 2003; 25: 325-327
22. Zhan N, Xiong YY, Lan J, Wang BC, Tian SF, Yu SP. Relationship between Helicobacter pylori infection and expression of c-myc, Bcl-2, and Bax protein in different gastric mucosa lesions. Aizheng 2003; 22: 1034-1037
23. Yang Y, Deng CS, Peng JZ, Wong BC, Lam SK, Xia HH. Effect of Helicobacter pylori on apoptosis and apoptosis related genes in gastric cancer cells. Mol Pathol 2003; 56: 19-24
24. Pan W, Ishii H, Ebihara Y, Gobe G. Prognostic use of growth characteristics of early gastric cancer and expression patterns of apoptotic, cell proliferation, and cell adhesion proteins. J Surg Oncol 2003; 82: 104-110
25. Lee KM, Lee DS, Yang JM, Ahn BM, Lee EH, Yoo JY, Kim YJ, Chung IS, Sun HS, Park DH. Effect of Helicobacter pylori on gastric epithelial cell kinetics and expression of apoptosis-related proteins in gastric carcinogenesis. Korean J Gastroenterol 2003; 42: 12-19
26. ras, c-erbB-2 and p53 and TCM syndrome in gastric precancerous lesions. Shijie Huaren Xiaohua Zazhi 2004; 12: 262-265
27. Yasui W, Yokozaki H, Fujimoto J, Naka K, Kuniyasu H, Tahara E. Genetic and epigenetic alterations in multistep carcinogenesis of the stomach. J Gastroenterol 2000; 35: 111-115
28. Tamura G. Genetic and epigenetic alterations of tumor suppressor and tumor-related genes in gastric cancer. Histol Histopathol 2002; 17: 323-329
29. Chou HK, Chen SL, Hsu CT, Chao YC, Tsao YP. Bcl-2 accelerates retinoic acid-induced growth arrest and recovery in human gastric cancer cells. Biochem J 2000; 348: 473-479
30. Wang YK, Ji XL, Ma NX. Expressions of P53, bcl-2 and c-erbB-2 genes in precarcinomatous gastric mucosa. Shijie Huaren Xiaohua Zazhi 1999; 7: 114-116
31. Gao HJ, Bai JF, Peng YS, Sun G, Zhao HL, Lu XZ, Zhao ZQ, Xiao SD. Expression and mutual relationship of tumor suppression gene and apoptosis regulating gene in gastric carcinoma and paracancerous tissues. Zhonghoa Xiaohua Zazhi 2000; 20: 178-181
32. Tang CZ, Lao SX, Hu L, Kuang ZS. Effect of Weiyanxiao on apoptosis and its relative genes expression in treating precancerosis of gastric cancer. Zhongguo Zhongxiyi Jiehe Piwei Zazhi 2000; 8: 263-264
33. Su M, Dai M, Lu X, Li H, Liu J. Effect of traditional Chinese medicine compounds Aining on the expression of apoptosis inducing genes of human gastric cancer cell. Zhongyaocai 2002; 25: 563-566