Countrywide spread of community- and hospital-acquired extended-spectrum β-lactamase (CTX-M-15)-producing Enterobacteriaceae in Lebanon

Journal of Clinical Microbiology

Volumn 43, Issue 7, 2005, Pages 3309-3313

  Moubareck, Carole ^a   Daoud, Ziad ^b   Hakimé, Noha I ^b   Hamzé, Monzer ^c,d   Mangeney, Nicole ^a   Matta, Hiam ^e   Mokhbat, Jacques E ^f   Rohban, Raymond ^g   Sarkis, Dolla Karam ^h   Doucet Populaire, Florence ^a,i  

^a FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

^b UNIVERSITY OF BALAMAND   (Lebanon)

^c LEBANESE UNIVERSITY   (Lebanon)

^d Nini Hospital   (Lebanon)

^e Arz Hospital   (Lebanon)

^f RIZK HOSPITAL   (Lebanon)

^g Saint Joseph Hospital Beirut   (Lebanon)

^h SAINT JOSEPH UNIVERSITY   (Lebanon)

ⁱ CENTRE HOSPITALIER DE VERSAILLES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CEFOTAXIME; CEFOXITIN; CEFTAZIDIME; CLAVULANIC ACID; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; PENICILLIN G;

ARTICLE; CITROBACTER FREUNDII; CLONAL VARIATION; COMMUNICABLE DISEASE; CONTROLLED STUDY; DNA RESTRICTION; DRUG POTENTIATION; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE; ENZYME SYNTHESIS; ESCHERICHIA COLI; FECES ANALYSIS; GENOTYPE; HEALTH CARE PERSONNEL; HOSPITAL INFECTION; HUMAN; KLEBSIELLA PNEUMONIAE; LEBANON; MAJOR CLINICAL STUDY; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; STRAIN IDENTIFICATION;

ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; BETA-LACTAMS; COMMUNITY-ACQUIRED INFECTIONS; CROSS INFECTION; DRUG RESISTANCE, BACTERIAL; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; HUMANS; LEBANON; MICROBIAL SENSITIVITY TESTS; POLYMERASE CHAIN REACTION;

CITROBACTER FREUNDII; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE;

EID: 22144481328     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.43.7.3309-3313.2005     Document Type: Article

References (36)

1. Arlet, G., M. Rouveau, I. Casin, P. J. Bouvet, P. H. Lagrange, and A. Philippon. 1994. Molecular epidemiology of Klebsiella pneumoniae strains that produce SHV-4 β-lactamase and which were isolated in 14 French hospitals. J. Clin. Microbiol. 32:2553-2558.
2. Bonnet, R. 2004. Growing group of extended-spectrum β-lactamases: the CTX-M enzymes. Antimicrob. Agents Chemother. 48:1-14.
3. Bonnet, R., C. Dutour, J. L. Sampaio, C. Chanal, D. Sirot, R. Labia, C. De Champs, and J. Sirot. 2001. Novel cefotaximase (CTX-M-16) with increased catalytic efficiency due to substitution Asp-240→Gly. Antimicrob. Agents Chemother. 45:2269-2275.
4. Bradford, P. A. 2001. Extended-spectrum β-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin. Microbiol. Rev. 14:933-951.
5. Casin, I., J. Breuil, A. Brisabois, F. Moury, F. Grimont, and E. Collatz. 1999. Multidrug-resistant human and animal Salmonella typhimurium isolates in France belong predominantly to a DT104 clone with the chromosome- and integron-encoded β-lactamase PSE-1. J. Infect. Dis. 179:1173-1182.
6. Chanawong, A., F. H. M'Zali, J. Heritage, A. Lulitanond, and P. M. Hawkey. 2001. SHV-12, SHV-5, SHV-2a, and VEB-1 extended-spectrum β-lactamases in Gram-negative bacteria isolated in a university hospital in Thailand. J. Antimicrob. Chemother. 48:839-852.
7. Daoud, Z., and N. Hakime. 2003. Prevalence and susceptibility patterns of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a general university hospital in Beirut, Lebanon. Rev. Esp. Quimioter. 16:233-238.
8. Eckert, C., V. Gautier, M. Saladin-Allard, N. Hidri, C. Verdet, Z. Ould-Hocine, G. Barnaud, F. Delisle, A. Rossier, T. Lambert, A. Philippon, and G. Arlet. 2004. Dissemination of CTX-M-type β-Lactamases among clinical isolates of Enterobacteriaceae in Paris, France. Antimicrob. Agents Chemother. 48:1249-1255.
9. Gniadkowski, M., A. Palucha, P. Grzesiowski, and W. Hryniewicz. 1998. Outbreak of ceftazidime-resistant Klebsiella pneumoniae in a pediatric hospital in Warsaw, Poland: clonal spread of the TEM-47 extended-spectrum β-lactamase (ESBL)-producing strain and transfer of a plasmid carrying the SHV-5-like ESBL-encoding gene. Antimicrob. Agents Chemother. 42:3079-3085.
10. Gouby, A., C. Neuwirth, G. Bourg, N, Bouziges, M. J. Carles-Nurit, E. Despaux, and M. Ramuz. 1994. Epidemiological study by pulsed-field gel electrophoresis of an outbreak of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in a geriatric hospital. J. Clin. Microbiol. 32:301-305.
11. Hacek, D. M., P. Bednarz, G. A. Noskin, T. Zembower, and L. R. Peterson. 2001. Yield of vancomycin-resistant enterococci and multidrug-resistant Enterobacteriaceae from stools submitted for Clostridium difficile testing compared to results from a focused surveillance program. J. Clin. Microbiol. 39:1152-1154.
12. Jarlier, V., M. H. Nicolas, G. Fournier, and A. Philippon. 1988. Extended broad-spectrum β-lactamases conferring transferable resistance to newer β-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns. Rev. Infect. Dis. 10:867-878.
13. Jeong, S. H., I. K. Bae, J. H. Lee, S. G. Sohn, G. H. Kang, G. J. Jeon, Y. H. Kim, B. C. Jeong, and S. H. Lee. 2004. Molecular characterization of extended-spectrum β-lactamases produced by clinical isolates of Klebsiella pneumoniae and Escherichia coli from a Korean nationwide survey. J. Clin. Microbiol. 42:2902-2906.
14. Katsanis, G. P., J. Spargo, M. J. Ferraro, L. Sutton, and G. A. Jacoby. 1994. Detection of Klebsiella pneumoniae and Escherichia coli strains producing extended-spectrum β-lactamases. J. Clin. Microbiol. 32:691-696.
15. Labia, R., and M. Barthelemy. 1979. "Beta-lactamase enzymogram": an agar adaptation of the iodometric method. Ann. Microbiol. 130B:295-304. (In French.)
16. Lartigue, M. F., L. Poirel, C. Heritier, V. Tolun, and P. Nordmann. 2003. First description of CTX-M-15-producing Klebsiella pneumoniae in Turkey. J. Antimicrob. Chemother. 52:315-316.
17. Livermore, D. M. 1995. β-Lactamases in laboratory and clinical resistance. Clin. Microbiol. Rev. 8:557-584.
18. Moubareck, C., M. Hamze, Z. Daoud, F. X. Weill, and F. Doucet-Populaire. 2005. First extended-spectrum β-lactamase (CTX-M-15)-producing Salmonella enterica serotype Typhimurium identified in Lebanon. Antimicrob. Agents Chemother. 49:864-865.
19. Mulgrave, L., and P. V. Attwood. 1993. Characterization of an SHV-5 related extended broad-spectrum β-lactamase in Enterobacteriaceae from Western Australia. Pathology 25:71-75.
20. Mulvey, M. R., E. Bryce, D. Boyd, M. Ofner-Agostini, S. Christianson, A. E. Simor, and S. Paton. 2004. Ambler class A extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella spp. in Canadian hospitals. Antimicrob. Agents Chemother. 48:1204-1214.
21. Mulvey, M. R., G. Soule, D. Boyd, W. Demczuk, and R. Ahmed. 2003. Characterization of the first extended-spectrum β-lactamase-producing Salmonella isolate identified in Canada. J. Clin. Microbiol. 41:460-462.
22. Munday, C. J., G. M. Whitehead, N. J. Todd, M. Campbell, and P. M. Hawkey. 2004. Predominance and genetic diversity of community- and hospital-acquired CTX-M extended-spectrum β-lactamases in York, UK. J. Antimicrob. Chemother. 54:628-633.
23. Munday, C. J., J. Xiong, C. Li, D. Shen, and P. M. Hawkey. 2004. Dissemination of CTX-M type β-lactamases in Enterobacteriaceae isolates in the People's Republic of China. Int. J. Antimicrob. Agents 23:175-180.
24. Mushtaq, S., N. Woodford, N. Potz, and D. M. Livermore. 2003. Detection of CTX-M-15 extended-spectrum β-lactamase in the United Kingdom. J. Antimicrob. Chemother. 52:528-529.
25. Palucha, A., B. Mikiewicz, W. Hryniewicz, and M. Gniadkowski. 1999. Concurrent outbreaks of extended-spectrum β-lactamase producing organisms of the family Enterobacteriaceae in a Warsaw hospital. J. Antimicrob. Chemother. 44:489-499.
26. Perilli, M., E. Dell'Amico, B. Segatore, M. R. de Massis, C. Bianchi, F. Luzzaro, G. M. Rossolini, A. Toniolo, G. Nicoletti, and G. Amicosante. 2002. Molecular characterization of extended-spectrum β-lactamases produced by nosocomial isolates of Enterobacteriaceae from an Italian nationwide survey. J. Clin. Microbiol. 40:611-614.
27. Philippon, A., S. Ben Redjeb, G. Fournier, and A. Ben Hassen. 1989. Epidemiology of extended spectrum β-lactamases. Infection 17:347-354.
28. Poirel, L., M. Gniadkowski, and P. Nordmann. 2002. Biochemical analysis of the ceftazidime-hydrolyzing extended-spectrum β-lactamase CTX-M-15 and of its structurally related β-lactamase CTX-M-3. J. Antimicrob. Chemother. 50:1031-1034.
29. Poirel, L., T. Naas, T. Le, I., A. Karim, E. Bingen, and P. Nordmann. 2001. CTX-M-type extended-spectrum β-lactamase that hydrolyzes ceftazidime through a single amino acid substitution in the omega loop. Antimicrob. Agents Chemother. 45:3355-3361.
30. Prodinger, W. M., M. Fille, A. Bauernfeind, I. Stemplinger, S. Amann, B. Pfausler, C. Lass-Florl, and M. P. Dierich. 1996. Molecular epidemiology of Klebsiella pneumoniae producing SHV-5 β-lactamase: parallel outbreaks due to multiple plasmid transfer. J. Clin. Microbiol. 34:564-568.
31. Quinteros, M., M. Radice, N. Gardella, M. M. Rodriguez, N. Costa, D. Korbenfeld, E. Couto, and G. Gutkind. 2003. Extended-spectrum β-lactamases in Enterobacteriaceae in Buenos Aires, Argentina, public hospitals. Antimicrob. Agents Chemother. 47:2864-2867.
32. Soussy, C. J., G. Carret, J. D. Cavallo, H. Chardon, C. Chidiac, P. Choutet, P. Courvalin, H. Dabernat, H. Drugeon, L. Dubreuil, F. Goldstein, V. Jarlier, R. Leclercq, M. H. Nicolas-Chanoine, A. Philippen, C. Quentin, B. Rouveix, and J. Sirot. 2004. Bulletin de la Société Française de Microbiologie, p. 1 to 48. Comité de l'Antibiogramme de la Société Française de Microbiologie, Paris, France.
33. Valverde, A., T. M. Coque, M. P. Sanchez-Moreno, A. Rollan, F. Baquero, and R. Canton. 2004. Dramatic increase in prevalence of fecal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae during non-outbreak situations in Spain. J. Clin. Microbiol. 42:4769-4775.
34. Weill, F. X., J. D. Perrier-Gros-Claude, M. Demartin, S. Coignard, and P. A. Grimont. 2004. Characterization of extended-spectrum β-lactamase (CTX-M-15)-producing strains of Salmonella enterica isolated in France and Senegal. FEMS Microbiol. Lett. 238:353-358.
35. Yamasaki, K., M. Komatsu, T. Yamashita, K. Shimakawa, T. Ura, H. Nishio, K. Satoh, R. Washidu, S. Kinoshita, and M. Aihara. 2003. Production of CTX-M-3 extended-spectrum β-lactamase and IMP-1 metallo β-lactamase by five Gram-negative bacilli: survey of clinical isolates from seven laboratories collected in 1998 and 2000, in the Kinki region of Japan. J. Antimicrob. Chemother. 51:631-638.
36. Yu, W. L., K. C. Cheng, L. T. Wu, M. A. Pfaller, P. L. Winokur, and R. N. Jones. 2004. Emergence of two Klebsiella pneumoniae isolates harboring plasmid-mediated CTX-M-15 β-lactamase in Taiwan. Antimicrob. Agents Chemother. 48:362-363.