Mixed-model of affinity and hydrophobic interaction for drug retention in cell membrane chromatography

Journal of Liquid Chromatography and Related Technologies

Volumn 28, Issue 11, 2005, Pages 1651-1668

  He, Langchong ^a   Yang, Guangde ^a   Wang, Sicen ^a   Wei, Yinmao ^b   Geng, Xindu ^b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b NORTHWEST UNIVERSITY   (China)

Author keywords

Calcium antagonist; Cell membrane chromatography; Cell membrane stationary phase; Retention mechanism; Stoichiometric displacement model

Indexed keywords

CALCIUM; CELL MEMBRANES; CHROMATOGRAPHY; HYDROPHOBICITY; STOICHIOMETRY; SURFACE PROPERTIES;

CELL MEMBRANE STATIONARY PHASE (CMSP); DRUG RETENTION; MOBILE PHASES; MYOCARDIUM;

DRUG PRODUCTS;

CALCIUM ANTAGONIST; DILTIAZEM; NIFEDIPINE; NIMODIPINE; NITRENDIPINE; VERAPAMIL;

ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELL MEMBRANE CHROMATOGRAPHY; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG RETENTION; HEART MUSCLE; HYDROPHOBICITY; MATHEMATICAL MODEL; NONHUMAN; RABBIT; STOICHIOMETRY; THEORY;

ORYCTOLAGUS CUNICULUS;

EID: 22144471547     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-200060422     Document Type: Article

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