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Volumn 2, Issue 3, 2005, Pages 225-233

Relaxin in vascular physiology and pathophysiology: Possible implications in ischemic brain disease

Author keywords

Cardiovascular system; Central nervous system; Ischemia reperfusion; Nitric oxide

Indexed keywords

NITRIC OXIDE; RELAXIN;

EID: 22144468683     PISSN: 15672026     EISSN: None     Source Type: Journal    
DOI: 10.2174/1567202054368362     Document Type: Review
Times cited : (12)

References (94)
  • 1
    • 0030864780 scopus 로고    scopus 로고
    • Nitric oxide synthase and vasopressin in rat circumventricular organs. An immunohistochemical study
    • Alm, P, Skagerberg, G, Nylèn, A, Larsson, B, Anderson, KE. (1997) Nitric oxide synthase and vasopressin in rat circumventricular organs. An immunohistochemical study. Exp Brain Res 117: 59-66.
    • (1997) Exp Brain Res , vol.117 , pp. 59-66
    • Alm, P.1    Skagerberg, G.2    Nylèn, A.3    Larsson, B.4    Anderson, K.E.5
  • 2
    • 0028820363 scopus 로고
    • Relaxin depresses platelet aggregation: In vitro studies on isolated human and rabbit platelets
    • Bani, D, Bigazzi, M, Masini, E, Bani, G, Bani Sacchi, T. (1995) Relaxin depresses platelet aggregation: in vitro studies on isolated human and rabbit platelets. Lab Invest 73: 709-16.
    • (1995) Lab Invest , vol.73 , pp. 709-716
    • Bani, D.1    Bigazzi, M.2    Masini, E.3    Bani, G.4    Bani Sacchi, T.5
  • 3
    • 0031021409 scopus 로고    scopus 로고
    • Relaxin: A pleiotropic hormone
    • Bani, D. (1997). Relaxin: a pleiotropic hormone. Gen Pharmacol 28: 13-22.
    • (1997) Gen Pharmacol , vol.28 , pp. 13-22
    • Bani, D.1
  • 4
  • 5
    • 0031945701 scopus 로고    scopus 로고
    • Relaxin protects against myocardial injury caused by ischemia and reperfusion in rat heart
    • Bani, D, Masini, E, Bello, MG, Bigazzi, M, Bani Sacchi, T. (1998b) Relaxin protects against myocardial injury caused by ischemia and reperfusion in rat heart. Am J Pathol 152: 1367-1376.
    • (1998) Am J Pathol , vol.152 , pp. 1367-1376
    • Bani, D.1    Masini, E.2    Bello, M.G.3    Bigazzi, M.4    Bani Sacchi, T.5
  • 6
    • 32744462738 scopus 로고    scopus 로고
    • Basic progress and future therapeutic perspectives of relaxin in ischemic heart disease
    • Sherwood, OD, Ed., Jackson Lake Lodge, Moran, WY, USA. N Y Acad Sci . In press
    • Bani, D, Nistri, S, Bani Sacchi, T, Bigazzi, M. (2004) Basic progress and future therapeutic perspectives of relaxin in ischemic heart disease (invited review). In: Relaxin 2004 - 4th International Conference on Relaxin and Related Peptides. Sherwood, OD, Ed., Jackson Lake Lodge, Moran, WY, USA. N Y Acad Sci 2005. In press.
    • (2004) Relaxin 2004 - 4th International Conference on Relaxin and Related Peptides
    • Bani, D.1    Nistri, S.2    Bani Sacchi, T.3    Bigazzi, M.4
  • 7
    • 0035667474 scopus 로고    scopus 로고
    • The vasorelaxant hormone relaxin induces changes in liver sinusoid microcirculation: A morphologic study in the rat
    • Bani, D, Nistri, S, Quattrone, S, Bigazzi, M, Bani Sacchi, T. (2001) The vasorelaxant hormone relaxin induces changes in liver sinusoid microcirculation: a morphologic study in the rat. J Endocrinol 171: 541-549.
    • (2001) J Endocrinol , vol.171 , pp. 541-549
    • Bani, D.1    Nistri, S.2    Quattrone, S.3    Bigazzi, M.4    Bani Sacchi, T.5
  • 9
    • 0023689974 scopus 로고
    • Effects of relaxin on the microvasculature of mouse mammary gland
    • Bani, G, Bani Sacchi, T, Bigazzi, M, Bianchi, S. (1988) Effects of relaxin on the microvasculature of mouse mammary gland. Histol Histopath 3: 337-343.
    • (1988) Histol Histopath , vol.3 , pp. 337-343
    • Bani, G.1    Bani Sacchi, T.2    Bigazzi, M.3    Bianchi, S.4
  • 10
    • 0029088422 scopus 로고
    • Effects of relaxin on the endometrial stroma. Studies in mice
    • Bani, G, Maurizi, M, Bigazzi, M, Bani Sacchi, T. (1995) Effects of relaxin on the endometrial stroma. Studies in mice. Biol Reprod 53: 253-262.
    • (1995) Biol Reprod , vol.53 , pp. 253-262
    • Bani, G.1    Maurizi, M.2    Bigazzi, M.3    Bani Sacchi, T.4
  • 14
    • 0022536299 scopus 로고
    • The local administration of relaxin induces changes in the microcirculation of the rat mesocaecum
    • Bigazzi, M, Del Mese, A, Petrucci, F, Casali, R, Novelli, GP. (1986) The local administration of relaxin induces changes in the microcirculation of the rat mesocaecum. Acta Endocrinol 112: 296-299.
    • (1986) Acta Endocrinol , vol.112 , pp. 296-299
    • Bigazzi, M.1    Del Mese, A.2    Petrucci, F.3    Casali, R.4    Novelli, G.P.5
  • 15
    • 0003350526 scopus 로고
    • Relaxin and the cardiocirculatory system
    • MacLennan, AH, Tregear, G, Bryant-Greenwood, GD, Eds., World Scientific Publishing: Singapore
    • Bigazzi, M, Bani, D, Bani, G, Bani Sacchi, T. (1995) Relaxin and the cardiocirculatory system. In: Progress in Relaxin Reasearch. MacLennan, AH, Tregear, G, Bryant-Greenwood, GD, Eds., World Scientific Publishing: Singapore, pp. 499-507.
    • (1995) Progress in Relaxin Reasearch , pp. 499-507
    • Bigazzi, M.1    Bani, D.2    Bani, G.3    Bani Sacchi, T.4
  • 16
    • 0019207583 scopus 로고
    • Hormones families: Pancreatic hormones and homologous growth factors
    • Blundell, TL, Humbel, RE. (1980) Hormones families: pancreatic hormones and homologous growth factors. Nature 287: 781-787.
    • (1980) Nature , vol.287 , pp. 781-787
    • Blundell, T.L.1    Humbel, R.E.2
  • 17
    • 0019457815 scopus 로고
    • Effects of ischemia and reperfusion on calcium exchange and mechanical function in isolated rabbit myocardium
    • Bourdillon, PDV, Poole-Wilson, PA. (1981) Effects of ischemia and reperfusion on calcium exchange and mechanical function in isolated rabbit myocardium. Cardiovasc Res 15: 121-130.
    • (1981) Cardiovasc Res , vol.15 , pp. 121-130
    • Bourdillon, P.D.V.1    Poole-Wilson, P.A.2
  • 18
    • 0022402059 scopus 로고
    • Myocardial reperfusion: A double edged sword
    • Braunwald, E, Kloner, R. (1985) Myocardial reperfusion: a double edged sword. J Clin Invest 76: 1713-1719.
    • (1985) J Clin Invest , vol.76 , pp. 1713-1719
    • Braunwald, E.1    Kloner, R.2
  • 20
    • 0036734781 scopus 로고    scopus 로고
    • Restricted, but abundant, expression of the novel rat gene-3 (R3) relaxin in the dorsal tegmental region of the brain
    • Burazin, TCD, Bathgate, RAD, Macris, M, Layfield, S, Gundlach, AL, Tregear, GW. (2002) Restricted, but abundant, expression of the novel rat gene-3 (R3) relaxin in the dorsal tegmental region of the brain. J Neurochem 82: 1553-1557.
    • (2002) J Neurochem , vol.82 , pp. 1553-1557
    • Burazin, T.C.D.1    Bathgate, R.A.D.2    Macris, M.3    Layfield, S.4    Gundlach, A.L.5    Tregear, G.W.6
  • 21
    • 0003328922 scopus 로고
    • Use of relaxin in the treatment of scleroderma
    • Casten, GG, Boucek, RJ. (1958) Use of relaxin in the treatment of scleroderma. JAMA 166: 319-324.
    • (1958) JAMA , vol.166 , pp. 319-324
    • Casten, G.G.1    Boucek, R.J.2
  • 22
    • 0000660922 scopus 로고
    • A new approach to the management of obliterative peripheral arterial disease
    • Casten, GG, Gilmore, HR, Houghton, FE, Samuels, SS. (1960) A new approach to the management of obliterative peripheral arterial disease. Angiology 11: 408-414.
    • (1960) Angiology , vol.11 , pp. 408-414
    • Casten, G.G.1    Gilmore, H.R.2    Houghton, F.E.3    Samuels, S.S.4
  • 23
    • 0033043767 scopus 로고    scopus 로고
    • Endothelin mediates renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious rats
    • Conrad, KP, Gandley, RE, Ogawa, T, Nakanishi, S, Danielson, LA. (1999) Endothelin mediates renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious rats. Am J Physiol Renal Physiol 276: F767-F776.
    • (1999) Am J Physiol Renal Physiol , vol.276
    • Conrad, K.P.1    Gandley, R.E.2    Ogawa, T.3    Nakanishi, S.4    Danielson, L.A.5
  • 24
    • 3242794260 scopus 로고    scopus 로고
    • Emerging role of relaxin in renal and cardiovascular function
    • Conrad, KP, Novak, J. (2004) Emerging role of relaxin in renal and cardiovascular function. Am J Physiol Regul Integr Comp Physiol 287: 250-261.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.287 , pp. 250-261
    • Conrad, K.P.1    Novak, J.2
  • 25
    • 84981822993 scopus 로고
    • The effect of relaxin on the endometrium of monkeys- histological and histochemical studies
    • Dallenbach-Hellweg, G, Dawson, AB, Hisaw, FL. (1966) The effect of relaxin on the endometrium of monkeys- histological and histochemical studies. Am J Anat 119: 61-78.
    • (1966) Am J Anat , vol.119 , pp. 61-78
    • Dallenbach-Hellweg, G.1    Dawson, A.B.2    Hisaw, F.L.3
  • 26
    • 0033557269 scopus 로고    scopus 로고
    • Relaxin is a potent renal vasodilator in conscious rats
    • Danielson, LA, Sherwood, OD, Conrad, KP. (1999) Relaxin is a potent renal vasodilator in conscious rats. J Clin Invest 103: 525-533.
    • (1999) J Clin Invest , vol.103 , pp. 525-533
    • Danielson, L.A.1    Sherwood, O.D.2    Conrad, K.P.3
  • 27
    • 0027723009 scopus 로고
    • Action of relaxin on uterine contractions - A review
    • Downing, SJ, Hollingsworth, M. (1993) Action of relaxin on uterine contractions - a review. J Reprod Fertil 99: 275-282.
    • (1993) J Reprod Fertil , vol.99 , pp. 275-282
    • Downing, S.J.1    Hollingsworth, M.2
  • 29
    • 0036484303 scopus 로고    scopus 로고
    • Relaxin up-regulates inducible nitric oxide synthase expression and nitric oxide generation in rat coronary endothelial cells
    • Failli, P, Nistri, S, Quattrone, S, Mazzetti, L, Bigazzi, M, Bani Sacchi, T, Bani, D. (2001) Relaxin up-regulates inducible nitric oxide synthase expression and nitric oxide generation in rat coronary endothelial cells. FASEB J 16: 252-254.
    • (2001) FASEB J , vol.16 , pp. 252-254
    • Failli, P.1    Nistri, S.2    Quattrone, S.3    Mazzetti, L.4    Bigazzi, M.5    Bani Sacchi, T.6    Bani, D.7
  • 30
    • 0038676021 scopus 로고
    • The relaxative hormone of the corpus luteum. Its purification and concentration
    • Fevold, HL, Hisaw, FL, Meyer, RK. (1930) The relaxative hormone of the corpus luteum. Its purification and concentration. J Am Chem Soc 52: 3340-3348.
    • (1930) J Am Chem Soc , vol.52 , pp. 3340-3348
    • Fevold, H.L.1    Hisaw, F.L.2    Meyer, R.K.3
  • 32
    • 0028197422 scopus 로고
    • Brain angiotensin-II partially mediates the effects of relaxin on vasopressin and oxytocin release in anesthetized rats
    • Geddes, BJ, Parry, LJ, Summerlee, AJS. (1994) Brain angiotensin-II partially mediates the effects of relaxin on vasopressin and oxytocin release in anesthetized rats. Endocrinology 134: 1188-1192.
    • (1994) Endocrinology , vol.134 , pp. 1188-1192
    • Geddes, B.J.1    Parry, L.J.2    Summerlee, A.J.S.3
  • 33
    • 0029147781 scopus 로고
    • The emerging concept of relaxin as a centrally acting peptide hormone with hemodynamic actions
    • Geddes, BJ, Summerlee, AJ. (1995) The emerging concept of relaxin as a centrally acting peptide hormone with hemodynamic actions. J Neuroendocrinol 7: 411-417.
    • (1995) J Neuroendocrinol , vol.7 , pp. 411-417
    • Geddes, B.J.1    Summerlee, A.J.2
  • 35
    • 0003472007 scopus 로고
    • Influence of relaxin on mammary development in sexually immature female rats
    • Hamolsky, M, Sparrow, RC. (1945) Influence of relaxin on mammary development in sexually immature female rats. Proc Soc Exp Biol Med 60: 8-9.
    • (1945) Proc Soc Exp Biol Med , vol.60 , pp. 8-9
    • Hamolsky, M.1    Sparrow, R.C.2
  • 36
    • 0025903363 scopus 로고
    • Expression of the human relaxin H1 gene in the decidua, trophoblast and prostate
    • Hansell, DJ, Bryant-Greenwood, GD, Greenwood, FC. (1991) Expression of the human relaxin H1 gene in the decidua, trophoblast and prostate. J Clin Endocrinol Metab 72: 899-904.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 899-904
    • Hansell, D.J.1    Bryant-Greenwood, G.D.2    Greenwood, F.C.3
  • 37
    • 0022035645 scopus 로고
    • Leukocyte-endothelial interactions
    • Harlan, JM. (1985) Leukocyte-endothelial interactions. Blood 65: 513-525.
    • (1985) Blood , vol.65 , pp. 513-525
    • Harlan, J.M.1
  • 38
    • 0003412980 scopus 로고
    • Experimental relaxation of the pubic ligament of the guinea pig
    • Hisaw, FL. (1926) Experimental relaxation of the pubic ligament of the guinea pig. Proc Soc Exp Biol Med 23: 661-663.
    • (1926) Proc Soc Exp Biol Med , vol.23 , pp. 661-663
    • Hisaw, F.L.1
  • 39
    • 0014114657 scopus 로고
    • Effect of relaxin on the endothelium of endometrial blood vessels in monkey (Macaca mulatta)
    • Hisaw, FL, Hisaw, FL, Dawson, AB. (1967) Effect of relaxin on the endothelium of endometrial blood vessels in monkey (Macaca mulatta). Endocrinology 81: 375-385.
    • (1967) Endocrinology , vol.81 , pp. 375-385
    • Hisaw, F.L.1    Hisaw, F.L.2    Dawson, A.B.3
  • 40
    • 0034464024 scopus 로고    scopus 로고
    • The three subfamilies of leucine-rich repeat-containing G protein coupled receptors (LGR): Identification of LGR6 and LGR7 and the signalling mechanism of LGR7
    • Hsu, SY, Kudo, M, Chen, T, Nakabayashi, K, Bhalla, A, van der Spek, PJ, van Duin, M, Hsueh, AJW. (2002) The three subfamilies of leucine-rich repeat-containing G protein coupled receptors (LGR): identification of LGR6 and LGR7 and the signalling mechanism of LGR7. Mol Endocrinol. 14: 1257-1271.
    • (2002) Mol Endocrinol , vol.14 , pp. 1257-1271
    • Hsu, S.Y.1    Kudo, M.2    Chen, T.3    Nakabayashi, K.4    Bhalla, A.5    Van Der Spek, P.J.6    Van Duin, M.7    Hsueh, A.J.W.8
  • 42
    • 0021514136 scopus 로고
    • Relaxin gene expression in human ovaries and the predicted structure of a human preprorelaxin by analysis of cDNA clones
    • Hudson, P, John, M, Crawford, R, Haralambidis, J, Scanlon, D, Gorman, J, Tregear, G, Shine, J, Niall, H. (1984) Relaxin gene expression in human ovaries and the predicted structure of a human preprorelaxin by analysis of cDNA clones. EMBO J 3: 2333-2339.
    • (1984) EMBO J , vol.3 , pp. 2333-2339
    • Hudson, P.1    John, M.2    Crawford, R.3    Haralambidis, J.4    Scanlon, D.5    Gorman, J.6    Tregear, G.7    Shine, J.8    Niall, H.9
  • 44
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • Ignarro, LJ, Buga, GM, Wood, KS, Byrns, RE, Chaudhuri, G. (1987) Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 84: 9265-9269.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 9265-9269
    • Ignarro, L.J.1    Buga, G.M.2    Wood, K.S.3    Byrns, R.E.4    Chaudhuri, G.5
  • 45
    • 0025977048 scopus 로고
    • Signal transduction mechanisms involving nitric oxide
    • Ignarro, LJ. (1991) Signal transduction mechanisms involving nitric oxide. Biochem Pharmac 41: 485-490.
    • (1991) Biochem Pharmac , vol.41 , pp. 485-490
    • Ignarro, L.J.1
  • 46
    • 0024456659 scopus 로고
    • Expression of the human relaxin gene in the corpus luteum of the menstrual cycle and in the prostate
    • Ivell, R, Hunt, N, Khan-Dawood, F, Dawood, MY. (1989) Expression of the human relaxin gene in the corpus luteum of the menstrual cycle and in the prostate. Mol Cell Endocrinol 66: 251-255.
    • (1989) Mol Cell Endocrinol , vol.66 , pp. 251-255
    • Ivell, R.1    Hunt, N.2    Khan-Dawood, F.3    Dawood, M.Y.4
  • 47
    • 0027211759 scopus 로고
    • Sensory circumventricular organs and brain homeostatic pathways
    • Johnson, AK, Gross, PM. (1993) Sensory circumventricular organs and brain homeostatic pathways. FASEB J 7: 165-170.
    • (1993) FASEB J , vol.7 , pp. 165-170
    • Johnson, A.K.1    Gross, P.M.2
  • 48
    • 0026608441 scopus 로고
    • Cardiac effect of relaxin in rats
    • Kakouris, H, Eddie LW, Summers LJ. (1992) Cardiac effect of relaxin in rats. Lancet 339: 1076-1078.
    • (1992) Lancet , vol.339 , pp. 1076-1078
    • Kakouris, H.1    Eddie, L.W.2    Summers, L.J.3
  • 51
    • 0037384189 scopus 로고    scopus 로고
    • Seminal immunoreactive relaxin in domestic animals and its relationship to sperm motility as a possible index for predicting the fertilizing ability of sires
    • Kohsaka, T, Hamano, K, Sasada, H, Watanabe, S, Ogine, T, Suzuki, E, Nishida, S, Takahara, H, Sato, E. (2003) Seminal immunoreactive relaxin in domestic animals and its relationship to sperm motility as a possible index for predicting the fertilizing ability of sires. Int J Androl 26: 115-120.
    • (2003) Int J Androl , vol.26 , pp. 115-120
    • Kohsaka, T.1    Hamano, K.2    Sasada, H.3    Watanabe, S.4    Ogine, T.5    Suzuki, E.6    Nishida, S.7    Takahara, H.8    Sato, E.9
  • 52
    • 0036849160 scopus 로고    scopus 로고
    • Inotropic responses to human gene 2 (B29) relaxin in a rat model of myocardial infarction (MI): Effect of pertussis toxin
    • Kompa, AR, Samuel, CS, Summers, RJ. (2002) Inotropic responses to human gene 2 (B29) relaxin in a rat model of myocardial infarction (MI): Effect of pertussis toxin. Br J Pharmacol 137: 710-718.
    • (2002) Br J Pharmacol , vol.137 , pp. 710-718
    • Kompa, A.R.1    Samuel, C.S.2    Summers, R.J.3
  • 53
    • 0009495930 scopus 로고
    • Lipid peroxidation and myocardial damage: Cause or consequence?
    • Stam, H, van der Vusse, GJ, Eds., Steinkhoff Verlag, Darmstadt
    • Koster, JF, Biemond, P, Stam, H. (1986) Lipid peroxidation and myocardial damage: cause or consequence? In: Lipid metabolism in the normoxic and ischemic heart. Stam, H, van der Vusse, GJ, Eds., Steinkhoff Verlag, Darmstadt, pp 253-260.
    • (1986) Lipid Metabolism in the Normoxic and Ischemic Heart , pp. 253-260
    • Koster, J.F.1    Biemond, P.2    Stam, H.3
  • 55
    • 0037999625 scopus 로고
    • The action of aqueous corpus luteum extract upon uterine activity
    • Krantz, JC, Bryant, HH, Carr, CJ. (1950) The action of aqueous corpus luteum extract upon uterine activity. Surg Gynecol Obstet 90: 372-375.
    • (1950) Surg Gynecol Obstet , vol.90 , pp. 372-375
    • Krantz, J.C.1    Bryant, H.H.2    Carr, C.J.3
  • 56
    • 0029054871 scopus 로고
    • Relaxin acts directly on rat mammary nipples to stimulate their growth
    • Kuenzi, MJ, Connolly, BA, Sherwood, OD. (1995) Relaxin acts directly on rat mammary nipples to stimulate their growth. Endocrinology 136: 2943-2947.
    • (1995) Endocrinology , vol.136 , pp. 2943-2947
    • Kuenzi, M.J.1    Connolly, B.A.2    Sherwood, O.D.3
  • 57
    • 0028238064 scopus 로고
    • 2 in rat brain after severe forebrain ischemia and in endotoxic shock
    • 2 in rat brain after severe forebrain ischemia and in endotoxic shock. Brain Res 651: 353-356.
    • (1994) Brain Res , vol.651 , pp. 353-356
    • Lauritzen, I.1    Heurteaux, C.2    Lazdunski, M.3
  • 58
    • 0025819503 scopus 로고
    • Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia
    • Lefer, AM, Tsao, PS, Lefer, DJ, Ma, XI. (1991) Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia. FASEB J 5: 2029-2034.
    • (1991) FASEB J , vol.5 , pp. 2029-2034
    • Lefer, A.M.1    Tsao, P.S.2    Lefer, D.J.3    Ma, X.I.4
  • 59
    • 0027457146 scopus 로고
    • Pharmacology of the endothelium in ischemia-reperfusion and circulatory shock
    • Lefer, AM, Lefer, DJ. (1993) Pharmacology of the endothelium in ischemia-reperfusion and circulatory shock. Annu Rev Pharmacol Toxicol 33: 71-90.
    • (1993) Annu Rev Pharmacol Toxicol , vol.33 , pp. 71-90
    • Lefer, A.M.1    Lefer, D.J.2
  • 61
  • 62
    • 0025319303 scopus 로고
    • Ischemia reperfusion injury and histamina release in isolated and perfused guinea-pig heart: Pharmacological interventions
    • Masini, E, Bianchi, S, Gambassi, F, Palmerani, B, Pistelli, A, Carlomagno, L, Mannaioni, PF. (1990) Ischemia reperfusion injury and histamina release in isolated and perfused guinea-pig heart: pharmacological interventions. Agents Action 30: 198-201.
    • (1990) Agents Action , vol.30 , pp. 198-201
    • Masini, E.1    Bianchi, S.2    Gambassi, F.3    Palmerani, B.4    Pistelli, A.5    Carlomagno, L.6    Mannaioni, P.F.7
  • 63
    • 0028143544 scopus 로고
    • Effects of relaxin on mast cells. In vitro and in vivo studies in rats and guinea pigs
    • Masini, E, Bani, D, Bigazzi, M, Mannaioni, PF, Bani Sacchi, T. (1994) Effects of relaxin on mast cells. In vitro and in vivo studies in rats and guinea pigs. J Clin Invest 94: 1974-80.
    • (1994) J Clin Invest , vol.94 , pp. 1974-1980
    • Masini, E.1    Bani, D.2    Bigazzi, M.3    Mannaioni, P.F.4    Bani Sacchi, T.5
  • 64
    • 0030729675 scopus 로고    scopus 로고
    • Relaxin counteracts myocardial damage induced by ischemia-reperfusion in isolated guinea pig hearts: Evidence for an involvement of nitric oxide
    • Masini, E, Bani, D, Bello, MG, Bigazzi, M, Mannaioni, PF, Bani Sacchi, T. (1997) Relaxin counteracts myocardial damage induced by ischemia-reperfusion in isolated guinea pig hearts: evidence for an involvement of nitric oxide. Endocrinology 138: 4713-4720.
    • (1997) Endocrinology , vol.138 , pp. 4713-4720
    • Masini, E.1    Bani, D.2    Bello, M.G.3    Bigazzi, M.4    Mannaioni, P.F.5    Bani Sacchi, T.6
  • 65
    • 1442323685 scopus 로고    scopus 로고
    • Relaxin inhibits the activation of human neutrophils: Involvement of the nitric oxide pathway
    • Masini, E, Nistri, S, Vannacci, A, Bani Sacchi, T, Novelli, A, Bani, D. (2004) Relaxin inhibits the activation of human neutrophils: involvement of the nitric oxide pathway. Endocrinology 145: 1106-1112.
    • (2004) Endocrinology , vol.145 , pp. 1106-1112
    • Masini, E.1    Nistri, S.2    Vannacci, A.3    Bani Sacchi, T.4    Novelli, A.5    Bani, D.6
  • 66
    • 0026016313 scopus 로고
    • The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit
    • May, GR, Cook, P, Moore, PK, Page, CP. (1991) The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit. Br J Pharmacol 102: 759-763.
    • (1991) Br J Pharmacol , vol.102 , pp. 759-763
    • May, G.R.1    Cook, P.2    Moore, P.K.3    Page, C.P.4
  • 69
    • 0029958542 scopus 로고    scopus 로고
    • Identification of specific relaxin-binding sites in the cervix, mammary glands, nipples, small intestine and skin of pregnant pigs
    • Min, G, Sherwood, OD. (1996) Identification of specific relaxin-binding sites in the cervix, mammary glands, nipples, small intestine and skin of pregnant pigs. Biol Reprod 55: 1243-1252.
    • (1996) Biol Reprod , vol.55 , pp. 1243-1252
    • Min, G.1    Sherwood, O.D.2
  • 70
    • 4344564007 scopus 로고    scopus 로고
    • Relaxin receptors and nitric oxide synthases. Search for the missing link
    • Nistri, S, Bani, D. (2003a) Relaxin receptors and nitric oxide synthases. Search for the missing link. Reprod Biol Endocrinol 1: 5.
    • (2003) Reprod Biol Endocrinol , vol.1 , pp. 5
    • Nistri, S.1    Bani, D.2
  • 71
    • 0642364972 scopus 로고    scopus 로고
    • Relaxin inhibits lipopolysaccharide-induced adhesion of neutrophils to coronary endothelial cells by a nitric oxide-mediated mechanism
    • Nistri, S, Chiappini, L, Sassoli, C, Bani, D. (2003b) Relaxin inhibits lipopolysaccharide-induced adhesion of neutrophils to coronary endothelial cells by a nitric oxide-mediated mechanism. FASEB J 17: 2109-2111.
    • (2003) FASEB J , vol.17 , pp. 2109-2111
    • Nistri, S.1    Chiappini, L.2    Sassoli, C.3    Bani, D.4
  • 73
    • 0017067551 scopus 로고
    • Radioimmunoassay of relaxin in sera of various species using an antiserum to porcine relaxin
    • O'Byrne, EM, Steinetz, BG. (1976) Radioimmunoassay of relaxin in sera of various species using an antiserum to porcine relaxin. Proc Soc Exp Biol Med 152: 272-276.
    • (1976) Proc Soc Exp Biol Med , vol.152 , pp. 272-276
    • O'Byrne, E.M.1    Steinetz, B.G.2
  • 75
    • 0027199629 scopus 로고
    • Expression of relaxin mRNA and relaxin receptor in postnatal and adult rat brain and hearts
    • Osheroff, PL, Ho, W. (1993) Expression of relaxin mRNA and relaxin receptor in postnatal and adult rat brain and hearts. J Biol Chem 268: 15193-15199.
    • (1993) J Biol Chem , vol.268 , pp. 15193-15199
    • Osheroff, P.L.1    Ho, W.2
  • 76
    • 0025236675 scopus 로고
    • Mechanisms of the haemotensive action of porcine relaxin in anaesthetized rats
    • Parry, LJ, Potershi, RS, Summerlee, AJS, Jones, SA. (1990) Mechanisms of the haemotensive action of porcine relaxin in anaesthetized rats. J Neuroendocrinol 2: 53-58.
    • (1990) J Neuroendocrinol , vol.2 , pp. 53-58
    • Parry, L.J.1    Potershi, R.S.2    Summerlee, A.J.S.3    Jones, S.A.4
  • 77
    • 0028012739 scopus 로고
    • Effect of relaxin on blood pressure and the release of vasopressin and oxytocin in anesthetized rats during pregnancy and lactation
    • Parry, LJ, Poterski, RS, Summerle, AJ. (1994) Effect of relaxin on blood pressure and the release of vasopressin and oxytocin in anesthetized rats during pregnancy and lactation. Biol Reprod 50: 622-628.
    • (1994) Biol Reprod , vol.50 , pp. 622-628
    • Parry, L.J.1    Poterski, R.S.2    Summerle, A.J.3
  • 78
    • 0030988138 scopus 로고    scopus 로고
    • Nitric oxide synthase in models of focal ischemia
    • Samdani, AF, Dawson, TM, Dawson, VL. (1997) Nitric oxide synthase in models of focal ischemia. Stroke 28: 1283-1288.
    • (1997) Stroke , vol.28 , pp. 1283-1288
    • Samdani, A.F.1    Dawson, T.M.2    Dawson, V.L.3
  • 79
    • 0028138246 scopus 로고
    • Relaxin: Structure, functions, promises and nonevolution
    • Schwabe, C, Buellesbach, EE. (1994) Relaxin: structure, functions, promises and nonevolution. FASEB J 8: 1152-1160.
    • (1994) FASEB J , vol.8 , pp. 1152-1160
    • Schwabe, C.1    Buellesbach, E.E.2
  • 80
    • 0000563125 scopus 로고
    • Relaxin
    • Knobil, E Neill, J, Eds., New York, Raven Press
    • nd Edition. Knobil, E Neill, J, Eds., New York, Raven Press, pp. 861-1010.
    • (1994) nd Edition , pp. 861-1010
    • Sherwood, O.D.1
  • 81
    • 0021829026 scopus 로고
    • Chronic decrease of blood pressure by rat relaxin in spontaneously hypertensive rats
    • St-Louis, J, Massicotte, G. (1985) Chronic decrease of blood pressure by rat relaxin in spontaneously hypertensive rats. Life Sci 31: 1351-1357.
    • (1985) Life Sci , vol.31 , pp. 1351-1357
    • St-Louis, J.1    Massicotte, G.2
  • 83
    • 0028212442 scopus 로고
    • Role of the subfornical organ in the relaxin-induced prolongation of gestation in the rat
    • Summerlee, AJ, Wilson, BC. (1994) Role of the subfornical organ in the relaxin-induced prolongation of gestation in the rat. Endocrinology 134: 2115-2120.
    • (1994) Endocrinology , vol.134 , pp. 2115-2120
    • Summerlee, A.J.1    Wilson, B.C.2
  • 84
    • 0029036359 scopus 로고
    • Central administration of porcine relaxin stimulates drinking behaviour in rats: An effect mediated by central angiotensin II
    • Summerlee, AJS, Robertson, GF. (1995) Central administration of porcine relaxin stimulates drinking behaviour in rats: an effect mediated by central angiotensin II. Endocr J 3: 377-381.
    • (1995) Endocr J , vol.3 , pp. 377-381
    • Summerlee, A.J.S.1    Robertson, G.F.2
  • 86
    • 0023888174 scopus 로고
    • Immunocytochemical localization of peptides and other neurochemicals in the rat laterodorsal tegmental nucleus and adjacent area
    • Sutin, EL, Jacobowitz, DM. (1988) Immunocytochemical localization of peptides and other neurochemicals in the rat laterodorsal tegmental nucleus and adjacent area. J Comp Neurol 270: 243-270.
    • (1988) J Comp Neurol , vol.270 , pp. 243-270
    • Sutin, E.L.1    Jacobowitz, D.M.2
  • 87
    • 0027973395 scopus 로고
    • Evidence for a novel source of relaxin: Atrial cardiocytes
    • Taylor, MJ, Clark, CL. (1994) Evidence for a novel source of relaxin: atrial cardiocytes. J Endocrinol 143: R5-R8.
    • (1994) J Endocrinol , vol.143
    • Taylor, M.J.1    Clark, C.L.2
  • 88
    • 0029761252 scopus 로고    scopus 로고
    • Relaxin stimulates atrial natriuretic peptide secretion in perfused rat heart
    • Toth, M, Taskinen, P, Ruskoaho, H. (1996) Relaxin stimulates atrial natriuretic peptide secretion in perfused rat heart. J Endocrinol 150: 487-495.
    • (1996) J Endocrinol , vol.150 , pp. 487-495
    • Toth, M.1    Taskinen, P.2    Ruskoaho, H.3
  • 89
    • 0033037935 scopus 로고    scopus 로고
    • Relaxin stimulates expression on vascular endothelial growth factor in normal human endometrial cells in vitro and is associated with menometrorrhagia in women
    • Unemori, EN, Erikson, ME, Rocco, SE, Sutherland, KM, Parsell, DA, Mak, J, Grove, BH. (1999) Relaxin stimulates expression on vascular endothelial growth factor in normal human endometrial cells in vitro and is associated with menometrorrhagia in women. Hum Reprod 14: 800-806.
    • (1999) Hum Reprod , vol.14 , pp. 800-806
    • Unemori, E.N.1    Erikson, M.E.2    Rocco, S.E.3    Sutherland, K.M.4    Parsell, D.A.5    Mak, J.6    Grove, B.H.7
  • 90
    • 0022892427 scopus 로고
    • Uterine growth-promoting effects of relaxin: A morphometric and histological analysis
    • Vasilenko, P, Mead, JP, Weidmann, JE. (1986) Uterine growth-promoting effects of relaxin: A morphometric and histological analysis. Biol Reprod 35: 987-995.
    • (1986) Biol Reprod , vol.35 , pp. 987-995
    • Vasilenko, P.1    Mead, J.P.2    Weidmann, J.E.3
  • 92
    • 0022623625 scopus 로고
    • Histamine and cardiac arrhythmias
    • Wolff, AA, Levi, R. (1986) Histamine and cardiac arrhythmias. Circ Res 27: 1-16.
    • (1986) Circ Res , vol.27 , pp. 1-16
    • Wolff, A.A.1    Levi, R.2
  • 94
    • 0030881495 scopus 로고    scopus 로고
    • Nitric oxide in health and disease of the nervous system
    • Yun, HY, Dawson, VL, Dawson, TM. (1997) Nitric oxide in health and disease of the nervous system. Molecular Psychiatry 2: 300-310.
    • (1997) Molecular Psychiatry , vol.2 , pp. 300-310
    • Yun, H.Y.1    Dawson, V.L.2    Dawson, T.M.3


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