Postoperative loco-regional radiation therapy for breast cancer patients with four or more involved lymph nodes or extracapsular extension

Israel Medical Association Journal

Volumn 7, Issue 7, 2005, Pages 439-442

  Evron, Ella ^a,d   Barzily, Liat ^b,d   Rakowsky, Erika ^b,d   Ben Baruch, Noa ^c   Sulkes, Jaquelin ^b,d   Rizel, Shulamith ^b,d   Fenig, Eyal ^b,d  

^a ASSAF HAROFEH MEDICAL CENTER   (Israel)

^b RABIN MEDICAL CENTER   (Israel)

^c KAPLAN HOSPITAL   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

Breast cancer; Breast loco regional irradiation; Radiation therapy

Indexed keywords

FLUOROURACIL; MELPHALAN;

ADULT; AGED; ARTICLE; AXILLA; AXILLARY LYMPH NODE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PARTIAL MASTECTOMY; POSTOPERATIVE CARE; RECURRENCE RISK; RISK REDUCTION; THORAX WALL;

AXILLA; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LYMPH NODES; MASTECTOMY, MODIFIED RADICAL; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; POSTOPERATIVE CARE; PROSPECTIVE STUDIES; RADIOTHERAPY, ADJUVANT; THORACIC WALL; TREATMENT OUTCOME;

EID: 22144467319     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Ragaz J, Jackson SM, Le N, et al. Adjuvant radiotherapy and chemotherapy in node-positive premenopausal women with breast cancer. N Engl J Med 1997;337:956-62.
2. Overgaard M, Hansen PS, Overgaard J, et al. Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial. N Engl J Med 1997;337:949-55.
3. Wallgren A, Bonetti M, Gelber RD, et al. Risk factors for loco-regional recurrence among breast cancer patients: results from International Breast Cancer Study Group Trials I through VII. J Clin Oncol 2003;21:1205-13.
4. Fisher BJ, Perera FE, Cooke AL, et al. Extracapsular axillary node extension in patients receiving adjuvant systemic therapy: an indication for radiotherapy? Int J Radiat Oncol Biol Phys 1997;38: 551-9.
5. Fodor J, Toth J, Major T, Polgar C, Nemeth G. Incidence and time of occurrence of regional recurrence in stage I-II breast cancer: value of adjuvant irradiation. Int J Radiat Oncol Biol Phys 1999;44:281-7.
6. Fodot J, Polgar C, Peley G, Nemeth G. Management of the axilla in breast cancer: evidences and unresolved issues. Orv Hetil 2001;142:1941-50.
7. Schaapveld M, Otter R, de Vries EG, et al. Variability in axillary lymph node dissection for breast cancer. J Surg Oncol 2004;87: 4-12.
8. Louis-Sylvestre C, Clough K, Asselain B, et al. Axillary treatment in conservative management of operable breast cancer: dissection or radiotherapy? Results of a randomized study with 15 years of follow-up. J Clin Oncol 2004;22:97-101.
9. Fisher B, Jeong JH, Anderson S, Bryant J, Fisher ER, Wolmark N. Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation. N Engl J Med 2002;347:567-75.
10. Recht A, Edge SB, Solin LJ, et al. Postmastectomy radiotherapy: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 2001;19:1539-69.
11. Bartelink H. Post-mastectomy radiotherapy: recommended standards. Ann Oncol 2000;11:7-11.
12. Rakowsky E, Klein B, Kahan E, Derzne E, Lurie H. Prognostic factors in node-positive operable breast cancer patients receiving adjuvant chemotherapy. Breast Cancer Res Treat 1992;21:121-31.
13. Fyles AW, McCready DR, Manchul LA, et al. Tamoxifen with or without breast irradiation in women 50 years of age or older with early breast cancer. N Engl J Med 2004;351:963-70.
14. Delouche G, Bachelot F, Premont M, Kurtz JM. Conservation treatment of early breast cancer: long-term results and complications. Int J Radiat Oncol Biol Phys 1987;13:29-34.
15. Larson D, Weinstein M, Goldberg I, et al. Edema of the arm as a function of the extent of axillary surgery in patients with stage I-II carcinoma of the breast treated with primary radiotherapy. Int J Radiat Oncol Biol Phys 1986;12:1575-82.