Do elderly people with lung cancer benefit from palliative radiotherapy?

Lung Cancer

Volumn 49, Issue 2, 2005, Pages 193-202

  Turner, N J ^a   Muers, M F ^b   Haward, R A ^c   Mulley, G P ^d  

^a SEACROFT HOSPITAL   (United Kingdom)

^b LEEDS GENERAL INFIRMARY   (United Kingdom)

^c Arthington House   (United Kingdom)

^d ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Elderly; Lung cancer; Palliative radiotherapy

Indexed keywords

AGE DISTRIBUTION; AGED; ALOPECIA; ARTICLE; CONTROLLED STUDY; DYSPHAGIA; ELDERLY CARE; FEMALE; FEVER; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MEDICAL PRACTICE; MOUTH DISEASE; PALLIATIVE THERAPY; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION INJURY; SCORING SYSTEM; STATISTICAL SIGNIFICANCE;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SMALL CELL; COHORT STUDIES; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; PALLIATIVE CARE; PROGNOSIS; PROSPECTIVE STUDIES; QUALITY OF LIFE; TREATMENT OUTCOME;

EID: 22044454699     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2005.01.010     Document Type: Article

References (33)

1. Northern and Yorkshire Cancer Registry and Information Service Cancer Outcomes Monitoring. Cancer treatment policies and their effects on survival. Key sites study 2: Lung. Leeds: NYCRIS; 1999.
2. N.R. Parsons, and L. Somervaille Estimation and projection of population lung cancer trends (United Kingdom) Cancer Causes Control 11 2000 467 475
3. J.R. Simpson, M.E. Francis, R. Perez-Tamayo, R.D. Marks, and D.V. Rao Palliative radiotherapy for inoperable carcinoma of the lung: final report of a RTOG multi-institutional trial Int J Radiat Oncol Biol Phys 11 1985 751 758
4. M. Lupattelli, E. Maranzano, R. Bellavita, F. Chionne, S. Darwish, and F. Piro Short-course palliative radiotherapy in non-small-cell lung cancer: results of a prospective study Am J Clin Oncol 23 2000 89 93
5. MRC LCWP. Inoperable non-small-cell lung cancer (NSCLC): a Medical Research Council randomised trial of palliative radiotherapy with two fractions or ten fractions. Report to the Medical Research Council by its Lung Cancer Working Party. Br. J. Cancer 1991;63:265-70.
6. MRC LCWP. A Medical Research Council (MRC) randomised trial of palliative radiotherapy with two fractions or a single fraction in patients with inoperable non-small-cell lung cancer (NSCLC) and poor performance status. Medical Research Council Lung Cancer Working Party. Br. J. Cancer 1992;65:934-41.
7. MRC LCWP. Randomized trial of palliative two-fraction versus more intensive 13-fraction radiotherapy for patients with inoperable non-small cell lung cancer and good performance status. Medical Research Council Lung Cancer Working Party. Clin. Oncol. (R. Coll. Radiol.) 1996;8:167-75.
8. G.J. Rees, C.E. Devrell, V.L. Barley, and H.F. Newman Palliative radiotherapy for lung cancer: two versus five fractions Clin Oncol (R Coll Radiol) 9 1997 90 95
9. A. Bezjak, P. Dixon, M. Brundage, D. Tu, M.J. Palmer, and P. Blood Randomized phase III trial of single versus fractionated thoracic radiation in the palliation of patients with lung cancer (NCIC CTG SC.15) Int J Radiat Oncol Biol Phys 54 2002 719 728
10. U. Nestle, C. Nieder, K. Walter, U. Abel, D. Ukena, and G.W. Sybrecht A palliative accelerated irradiation regimen for advanced non-small-cell lung cancer vs. conventionally fractionated 60 GY: results of a randomized equivalence study Int J Radiat Oncol Biol Phys 48 2000 95 103
11. S. Sundstrom, R. Bremnes, U. Aasebo, S. Aamdal, R. Hatlevoll, and P. Brunsvig Hypofractionated palliative radiotherapy (17 Gy per two fractions) in advanced non-small-cell lung carcinoma is comparable to standard fractionation for symptom control and survival: a national phase III trial J Clin Oncol 22 2004 801 810
12. C.J. Patterson, M. Hocking, M. Bond, and C. Teale Retrospective study of radiotherapy for lung cancer in patients aged 75 years and over Age Ageing 27 1998 515 518
13. H.M. Hodkinson Evaluation of a mental test score for assessment of mental impairment in the elderly Age Ageing 1 1972 233 238
14. A.B. Miller, B. Hoogstraten, H. Staquet, and A. Winkler Reporting results of cancer treatment Cancer 47 1981 207 214
15. D.T. Wade, and C. Collin The Barthel ADL Index: a standard measure of physical disability? Int Disabil Stud 10 1988 64 67
16. M.E. Charlson, P. Pompei, K.L. Ales, and C.R. MacKenzie A new method of classifying prognostic comorbidity in longitudinal studies: development and validation J Chronic Dis 40 1987 373 383
17. N.K. Aaronson, S. Ahmedzai, B. Bergman, M. Bullinger, A. Cull, and N.J. Duez The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology J Natl Cancer Inst 85 1993 365 376
18. B. Bergman, N.K. Aaronson, S. Ahmedzai, S. Kaasa, and M. Sullivan The EORTC QLQ-LC13: a modular supplement to the EORTC Core Quality of Life Questionnaire (QLQ-C30) for use in lung cancer clinical trials. EORTC Study Group on Quality of Life Eur J Cancer 30A 1994 635 642
19. A.S. Zigmond, and R.P. Snaith The hospital anxiety and depression scale Acta Psychiatr Scand 67 1983 361 370
20. K.M. Hill, Z. Amir, M.F. Muers, C.K. Connolly, and C.E. Round Do newly diagnosed lung cancer patients feel their concerns are being met? Eur J Cancer Care 12 2003 35 45
21. D. Osoba, B. Zee, J. Pater, D. Warr, L. Kaizer, and J. Latreille Psychometric properties and responsiveness of the EORTC quality of Life Questionnaire (QLQ-C30) in patients with breast, ovarian and lung cancer Qual Life Res 3 1994 353 364
22. S. Kaasa, K. Bjordal, N. Aaronson, T. Moum, E. Wist, and S. Hagen The EORTC core quality of life questionnaire (QLQ-C30): validity and reliability when analysed with patients treated with palliative radiotherapy Eur J Cancer 31A 1995 2260 2263
23. G. Velikova, E.P. Wright, A.B. Smith, A. Cull, A. Gould, and D. Forman Automated collection of quality-of-life data: a comparison of paper and computer touch-screen questionnaires J Clin Oncol 17 1999 998 1007
24. B. Jones, P. Jarvis, J.A. Lewis, and A.F. Ebbutt Trials to assess equivalence: the importance of rigorous methods Br Med J 313 1996 36 39
25. P.M. Fayers, N.K. Aaronson, K. Bjordal, D. Curran, M. Groenvold On behalf of the EORTC Quality of Life Study Group The EORTC QLQ-C30 scoring manual 2nd ed. 1999 European Organisation for Research and Treatment of Cancer Brussels
26. J.A. Langendijk, G.P. ten Velde, N.K. Aaronson, J.M. de Jong, M.J. Muller, and E.F. Wouters Quality of life after palliative radiotherapy in non-small cell lung cancer: a prospective study Int J Radiat Oncol Biol Phys 47 2000 149 155
27. D. Bowers Statistics further from scratch 1997 John Wiley & Sons Ltd. Chichester
28. V. Carstairs, and R. Morris Deprivation and health in Scotland 1991 Aberdeen University Press
29. S.J. Falk, D.J. Girling, R.J. White, P. Hopwood, A. Harvey, and W. Qian Immediate versus delayed palliative thoracic radiotherapy in patients with unresectable locally advanced non-small cell lung cancer and minimal thoracic symptoms: randomised controlled trial Br Med J 325 2002 465
30. S. Capewell, M.F. Sudlow The Edinburgh Lung Cancer Group Performance and prognosis in patients with lung cancer Thorax 45 1990 951 956
31. S.R. Cohen, B.M. Mount, J.J. Tomas, and L.F. Mount Existential well-being is an important determinant of quality of life. Evidence from the McGill Quality of Life Questionnaire Cancer 77 1996 576 586
32. R.J. Stephens, P. Hopwood, D.J. Girling, and D. Machin Randomized trials with quality of life endpoints: are doctors' ratings of patients' physical symptoms interchangeable with patients' self-ratings? Qual Life Res 6 1997 225 236
33. A. Montazeri, R. Milroy, D. Hole, J. McEwen, and C.R. Gillis Quality of life in lung cancer patients: as an important prognostic factor Lung Cancer 31 2001 233 240