PKC sulfhydryl targeting by disulfiram produces divergent isozymic regulatory responses that accord with the cancer preventive activity of the thiuram disulfide

Antioxidants and Redox Signaling

Volumn 7, Issue 7-8, 2005, Pages 855-862

  Chu, Feng ^a   O'Brian, Catherine A ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; CYSTINE; DISULFIDE; DISULFIRAM; ISOENZYME; PHOSPHATIDYLSERINE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C GAMMA; THIOL DERIVATIVE;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER PREVENTION; CELL GROWTH; CELL STRAIN COS7; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DISULFIDE BOND; DRUG TARGETING; ENZYME ASSAY; ENZYME INACTIVATION; MOLECULAR WEIGHT; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN S THIOLATION; WESTERN BLOTTING;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; DISULFIDES; DISULFIRAM; DITHIOTHREITOL; ENZYME ACTIVATION; FREE RADICALS; INHIBITORY CONCENTRATION 50; ISOENZYMES; MOLECULAR STRUCTURE; NEOPLASMS; PROTEIN KINASE C; THIRAM;

EID: 22044453218     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2005.7.855     Document Type: Article

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