Exposure to human blood inactivates swine endothelial ecto-5′- nucleotidase

Nucleosides, Nucleotides and Nucleic Acids

Volumn 24, Issue 4, 2005, Pages 271-274

  Khalpey, Z ^a   Kalsi, K ^a   Yuen, A ^a   Karbowska, J ^b   Kochan, Z ^b   Slominska, E M ^b   Forni, M ^c   Bacci, M ^c   Macherini, M ^d   Batten, P ^a   Lavitrano, M ^e   Yacoub, M H ^a   Smolenski, R T ^a  

^a HAREFIELD HOSPITAL   (United Kingdom)

^b MEDICAL UNIVERSITY OF GDANSK   (Poland)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d UNIVERSITY OF SIENA   (Italy)

^e UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

Complement; Ecto 5 Nucleotidease; Endothelial cells; Nucleotides; Xenotransplantation

Indexed keywords

ADENOSINE; COMPLEMENT; ECTO 5' NUCLEOTIDASE;

ANIMAL CELL; AORTA; ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; DISEASE EXACERBATION; ENDOTHELIUM CELL; ENZYME INACTIVATION; EXPOSURE; HEART PERFUSION; HEAT; HUMAN; HYPERACUTE GRAFT REJECTION; IN VITRO STUDY; NONHUMAN; SWINE; WILD TYPE;

5'-NUCLEOTIDASE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; AORTA; BLOOD; COMPLEMENT SYSTEM PROTEINS; ENDOTHELIUM, VASCULAR; HUMANS; NUCLEOTIDES; PERFUSION; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; SWINE; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS;

SUS SCROFA;

EID: 22044451634     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-59707     Document Type: Article

References (8)

1. Waterworth, P.D.; Dunning, J.; Tolan, M.; et al. Life-supporting pig-to-baboon heart xenotransplantation. J. Heart Lung Transplant 1998, 17, 1201-1207.
2. Bach, F.H.; Winkler, H.; Ferran, C.; Hancock, W.W.; Robson, S.C. Delayed xenograft rejection. Immunol. Today 1996, 17, 379-384.
3. Cronstein, B.N.; Levin, R.I.; Philips, M.; et al. Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. J. Immunol. 1992, 148, 2201-2206.
4. Firestein, G.S.; Bullough, D.A.; Erion, M.D.; et al. Inhibition of neutrophil adhesion by adenosine and an adenosine kinase inhibitor. The role of selectins. J. Immunol. 1995, 154, 326-334.
5. Bouma, M.G.; van den Wildenberg, F.A.; Buurman, W.A. The anti-inflammatory potential of adenosine in ischemia-reperfusion injury: established and putative beneficial actions of a retaliatory metabolite. Shock 1997, 8, 313-320.
6. Bravery, C.A.; Batten, P.; Yacoub, M.H.; Rose, M.L. Direct recognition of SLA- and HLA-like class II antigens on porcine endothelium by human T cells results in T cell activation and release of interleukin-2. Transplantation 1995, 60, 1024-1033.
7. Kochan, Z.; Smolenski, R.T.; Yacoub, M.H.; Seymour, A.-M.L. Nucleotide and adenosine metabolism in different cell types in human and rat heart J. Mol. Cell. Cardiol. 1994, 26, 1497-1503.
8. Smolenski, RT.; Lachno, D.R.; Ledingham, S.J.M.; Yacoub, M.H. Determination of sixteen nucleotides, nucleosides and bases using high-performance liquid chromatography and its application to the study of purine metabolism in hearts for transplantation. J. Chromatogr. 1990, 527, 414-420.