The current state and prospect of de novo protein design

Progress in Biochemistry and Biophysics

Volumn 25, Issue 3, 1998, Pages 200-201

  Cao, Ao Neng ^a   Lai, Lu Hua ^a   Tang, You Qi ^a  

^a Institute of Physical Chemistry   (China)

Author keywords

De novo design; Prediction; Protein

Indexed keywords

EID: 22044451128     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Richardson J S, Richardson D C. The de novo design of protein structures. TIBS, 1989, 14 (July): 304-309
2. Rose G D, Creamer T P. Protein folding: prediting predicting. Proteins: Struct Funct Genet, 1994, 19 (1): 1-3
3. DeGrado W F, Wasserman Z R, Lear J D. Protein design, a minimalist approach. Science, 1989, 243 (4891/4892): 622-628
4. Mutter M. Nature's rules and chemist's tools: a way for creating novel proteins. Trends Biochem Sci, 1988, 13 (7): 260-265
5. Jones D T. De novo protein design using pairwise potentials and a genetic algorithm. Protein Sci, 1994, 3 (4): 567-574
6. Lai Luhua, Guo Feng, Xu Xiaojie et al. Automatic protein de novo design by genetic algorithm and 3D profile. J Biomol Struct Dyn, 1995, 12 (6): a128
7. Betz S F, Raleigh D P, DeGrado W F. De novo protein design: from molten globules to native-like states. Curr Opin Struct Biol, 1993, 3 (4): 601-610
8. Cordes M H J, Davidson A R, Saner R T. Sequence space, folding and protein design. Curr Opin Struct Biol, 1996, 6 (1): 3-10
9. Ramírez-Alvarado M, Blanco F J, Serramo L. De novo design and structural analysis of a model β-hairpin peptide system. Nature Struct Biol, 1996, 3 (7): 604-612
10. Goraj K, Renard A, Martial J A. Synthesis, purification and initial structural characterization of octarellin, a de novo polypeptide modelled on the α/β-barrel proteins. Protein Eng, 1990, 3 (4): 259-266
11. Struthers M D, Cheng R P, Imperiali P. Design of a monomeric 23-residue polypepide with defined tertiary structure. Science, 1996, 271 (5247): 342-345
12. Fedorov A N, Dolgikh D A, Chemeris V V et al. De novo protein design, synthesis and study of Albebetin, a polypeptide with a predetermined three-dimensional structure. J Mol Biol, 1992, 225 (4): 927-931
13. Bella J, Eaton M, Brodsky B et al. Crystal and molecular structure of a collagen-like peptide at 1.9Å resolution. Science, 1994, 266 (5182): 75-81
14. Pessi A, Bianchi E, Creamer A et al. A designed metal-binding protein with a novel fold. Nature, 1993, 362 (6418): 367-369
15. 2 zinc finger peptide. Proc Natl Acad Sci USA, 1992, 89 (11): 4796-4800
16. Sasaki T, Kaiser E T. Synthesis and structural stability of helichrome as an artificial hemeproteins. Biopolymers, 1990, 29 (1): 79-88