A novel H28Y mutation in LEC rats leads to decreased NAT protein stability in vivo and in vitro

Journal of Pineal Research

Volumn 39, Issue 1, 2005, Pages 84-90

  Huang, Zheping ^a   Deng, Jie ^b   Borjigin, Jimo ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Circadian rhythms; Long Evans cinnamon rats; Melatonin; Pineal gland; Protein stability; Serotonin N acetyltransferase

Indexed keywords

ACYLTRANSFERASE; ARALKYLAMINE ACETYLTRANSFERASE; HISTIDINE; MELATONIN; TYROSINE;

ANIMAL TISSUE; ARTICLE; CATALYSIS; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVITY; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PINEAL BODY; PROTEIN DEGRADATION; PROTEIN STABILITY; RAT; RAT STRAIN; WILSON DISEASE;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SUBSTITUTION; ANIMALS; ARYLALKYLAMINE N-ACETYLTRANSFERASE; CATION TRANSPORT PROTEINS; CELL LINE; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOLENTICULAR DEGENERATION; HUMANS; MELATONIN; POINT MUTATION; RATS; RATS, INBRED LEC; RATS, SPRAGUE-DAWLEY;

EID: 22044443755     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2005.00222.x     Document Type: Article

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