Differential effect of zileuton, a 5-lipoxygenase inhibitor, against nociceptive paradigms in mice and rats

Pharmacology Biochemistry and Behavior

Volumn 81, Issue 3, 2005, Pages 433-439

  Singh, Vijay Pal ^a   Patil, Chandrashekhar S ^a   Kulkarni, Shrinivas K ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

5 LOX: 5 Lipoxygenase; Inflammatory pain; LTs: leukotrienes; Nociception

Indexed keywords

ACETIC ACID; CARRAGEENAN; LEUKOTRIENE B4 RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOXYGENASE INHIBITOR; MONTELUKAST; ROFECOXIB; UNCLASSIFIED DRUG; ZAFIRLUKAST; ZILEUTON; ZK 158252;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOPSY; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; FOOT; HISTOLOGY; HOT PLATE TEST; HYPERALGESIA; INFLAMMATION; MOUSE; NOCICEPTION; NONHUMAN; PAIN; PAIN ASSESSMENT; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; STIMULUS RESPONSE; TAIL FLICK TEST; WRITHING TEST;

ACETATES; ACETIC ACID; ANALGESICS; ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; CAPILLARY PERMEABILITY; CARRAGEENAN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HINDLIMB; HYDROXYUREA; HYPERALGESIA; INFLAMMATION; LEUKOTRIENE ANTAGONISTS; LIPOXYGENASE INHIBITORS; MALE; MICE; PAIN; PAIN MEASUREMENT; QUINOLINES; RATS; RATS, WISTAR; RECEPTORS, LEUKOTRIENE B4; TOSYL COMPOUNDS;

EID: 21944457950     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2005.03.015     Document Type: Article

References (34)

1. 2 and epinephrine in the rat Exp Brain Res 148 2003 482 487
2. G.W. Carter, P.R. Young, D.H. Albert, J. Bousla, R. Dyer, and R.L. Bell 5-Lipoxygenase inhibitory activity of zileuton J Pharmacol Exp Ther 256 1991 929 937
3. H.O. Collier, and C. Schneider Nociceptive response to prostaglandins and analgesics action of aspirin and morphine Nat New Biol 236 1972 141 143
4. 4 in antigen-induced mechanical hyperalgesia in immunized rats Br J Pharmacol 139 2003 1135 1145
5. K.D. Davis, R.A. Meyer, and J.N. Campbell Chemosensitivity and sensitization of nociceptive afferents that innervate hairy skin of monkey J Neurophysiol 69 1993 1071 1081
6. R.F. Feitosa, G.B. Melciades, A.M. Assreuy, M.F. Rocha, R.A. Ribeiro, and A.A. Lima The pharmacological profile of ovalbumin-induced paw oedema in rats Mediat Inflamm 11 3 2002 155 163
7. C.D. Funk Prostaglandins and leukotrienes: advances in eicosanoids biology Science 294 2001 1875 1890
8. A. Gilbert, C. Le Gouill, C. Thompson, G. Pasternak, J. Stankova, and M. RolaPleszczynski Expression and modulation of cysteinyl leukotrienes receptor 1 (cysltr 1) in the central nervous system Soc Neurosci Abstr 695 2003 11
9. D.E. Griswold, P. Marshall, L. Martin, E.F. Webb, and B. Zabko-Potapovich Analgetic activity of SK&F 105809, a dual inhibitor of arachidonic acid metabolism Agents Actions Suppl 32 1991 113 117
10. N.K. Jain, S.K. Kulkarni, and A. Singh Role of cysteinyl leukotrienes in nociceptive and inflammatory conditions in experimental animals Eur J Pharmacol 43 2001 85 92
11. N.K. Jain, S.K. Kulkarni, and A. Singh Differential antinociceptive effect of cyclooxygenase inhibitors in acetic acid-induced chemonociception in mice Analgesia 5 2001 211 216
12. 2 and leukotriene in radicular pain induced by herniated nucleus pulposus J Orthop Res 19 2001 472 477
13. 4 produces hyperalgesia that is dependent on polymorphonuclear leukocytes Science 225 1984 743 744
14. J.D. Levine, J. Gooding, P. Donatoni, L. Borden, and E.J. Goetzl The role of polymorhonuclear leukocyte in hyperalgesia J Neurosci 5 1985 3025 3029
15. J.D. Levine, D. Lam, Y.O. Taiwo, P. Donatoni, and E.J. Goetzl Hyperalgesic properties of 15-lipoxygenase products of arachidonic acid Proc Nalt Acad Sci U S A 83 1986 5331 5334
16. E. Marry Common animal models for spasticity and pain J Rehabil Res Dev 40 2003 41 54
17. H.A. Martin, A.I. Basbaum, G.C. Kwait, E.J. Goetzl, and J.D. Levine Leukotriene and prostaglandin sensitization of cutaneous high threshold C and A-delta mechanoreceptors in the hairy skin of the rat hindlimbs Neuroscience 22 1987 651 659
18. 4 decreases the mechanical thresholds of C and A-delta mechanoreceptors in the hairy skin of the rat J Neurophysiol Neurosci 60 1988 438 445
19. O.A. Olajide, J.M. Makinde, and D.T. Okpako Evaluation of anti-inflammatory property of the extract of Combertum micranthum G. Don (Combretaceae) Inflammopharmacology 11 2003 293 298
20. C.S. Patil, N.K. Jain, S.K. Kulkarni, and A. Singh Modulatory role of cyclooxygenase inhibitors on sildenafil-induced antinociception Pharmacology 69 2003 183 189
21. B.M. Peskar, M. Trautmann, P. Nowak, and B.A. Perskar Release of 15-hydroxy-5, 8,11,13-eicosatetraenoic acid and cysteinyl-leukotrienes in carrageenan-induced inflammation: effect of nonsteroidal anti-inflammatory drugs Agents Actions 33 1991 240 246
22. C.A. Porro, and M. Cavazzuti Spatial and temporal aspects of spinal cord and brain stem activation in the formalin pain model Prog Neurobiol 41 1993 565 607
23. 1 in the rat paw Prostaglandins 25 1983 193 203
24. A. Rueff, and A. Dray Sensitization of peripheral afferent fibers in the in vitro neonatal rat spinal cord-tail by bradykinin and prostaglandins Neuroscience 54 1993 527 535
25. V.P. Singh, N.K. Jain, and S.K. Kulkarni On the antinociceptive effect of fluoxetine, a selective serotonin reuptake inhibitor Brain Res 915 2001 218 226
26. V.P. Singh, N.K. Jain, and S.K. Kulkarni Fluoxetine, a selective serotonin reuptake inhibitor modulates inflammatory and neuropathic pain in the rat Inflammopharmacolgy 9 2002 217 346
27. V.P. Singh, C.S. Patil, and S.K. Kulkarni Effect of zileuton in radicular pain induced by herniated nucleus pulposus in rats Inflammopharmacology 12 2004 189 195
28. V.P. Singh, C.S. Patil, and S.K. Kulkarni Effect of 5-lipoxygenase inhibition on events associated with inflammatory bowel disease in rats Ind J Exp Biol 42 2004 667 673
29. D. Steinhilber 5-Lipoxygenase: a target for anti-inflammatory drugs revisited Curr Med Chem 6 1999 69 83
30. C.R. Tonussi, and S.H. Ferreira Tumor necrosis factor-alpha mediates carrageenan-induced knee-joint incapacitation and also triggers overt nociception in previously inflamed rat knee-joint Pain 82 1999 81 87
31. T. Trang, B. McNaull, R. Quiruion, and K. Jhamandas Involvement of spinal lipoxygenase metabolites in the hyperalgesia and opioid tolerance Eur J Pharmacol 491 2004 21 30
32. J.R. Vane, and M.R. Blotting New insights into the mode of action of non steroidal anti-inflammatory drugs Inflamm Res 44 1995 1 10
33. J.L. Wallace, and Li Ma Inflammatory mediators in gastrointestinal defense and injury Exp Biol Med 226 2001 1003 1015
34. M. Zimmermann Peripheral and central nervous mechanisms of nociception, pain and pain therapy: facts and hypothesis Bonica J.J. Liebeskind D.G. Albe-Fessard Advances in pain research and therapy 1979 Raven Press New York 3 32