Ethanol's effect on rat pituitary adrenal axis is prevented by purine metabolic pathway inhibitors

Proceedings of the Society for Experimental Biology and Medicine

Volumn 220, Issue 2, 1999, Pages 112-118

  Szabó, Jozsef ^a   Bruckner, Geza ^b   Medveczky, Istvan ^a   Kósa, Emma ^a   Balogh, Adam ^c  

^a UNIVERSITY OF VETERINARY MEDICINE   (Hungary)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF SZEGED   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ALCOHOL; CORTICOSTERONE; CORTICOTROPIN; MERCAPTOPURINE; URATE; XANTHINE DEHYDROGENASE;

ALCOHOL METABOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; CORTICOTROPIN RELEASE; DOSE RESPONSE; FEMALE; HORMONE DETERMINATION; HYPOPHYSIS ADRENAL SYSTEM; HYPOPHYSIS CELL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; NONHUMAN; PURINE METABOLISM; RAT; TISSUE CULTURE;

EID: 21944435261     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1373.1999.d01-18.x     Document Type: Article

References (37)

1. Ellis FW. Effect of ethanol on plasma corticosterone levels. J Pharmacol Exp Ther 153:121-127, 1966.
2. Wright J. Endocrine effects of alcohol. Clin Endocrinol Metab 7:351-367, 1978.
3. Cicero TJ. Neuroendocrinological effect of alcohol. Annu Rev Med 32:123-142, 1981.
4. Redei E, Branch BJ, Newman Taylor A. Direct effect of ethanol on adrenocorticotropin (ACTH) release in vitro. J Pharmacol Exp Ther 237:59-64, 1986.
5. Rivier C, Bruhn T, Vale W. Effect of ethanol on hypothalamicpituitary-adrenal axis in the rat: Role of corticotropin-releasing factor (CRF). J Pharmacol Exp Ther 229:127-131, 1984.
6. Thurman RG. Hepatic alcohol oxidation and its metabolic liability. Fed Proc 36:1640-1646, 1977.
7. Bühler R, Pestalozzi D, Hess M, Von Wartburg PJ. Immunohistochemical localization of alcohol dehydrogenase in human kidney, endocrine organs, and brain. Pharmacol Biochem Behav 18(Suppl 1): 55-59, 1983.
8. Handler JA, Thurman RG. Redox interactions between catalase and alcohol dehydrogenase pathways of ethanol metabolism in the perfused rat liver. J Biol Chem 265:1510-1515, 1990.
9. Lenzen S, Drinkgern J, Tiedge M. Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic Biol Med 23:463-466, 1996.
10. Hartz JW, Funakoshi S, Deutsch HF. The levels of Superoxide dismutase and catalase in human tissues as determined immunochemically. Clin Chim Acta 46:125-132, 1973.
11. Sohda T, Shimizu M, Kamimura S, Okumura M. Immunohistochemical demonstration of ethanol-inducible P450 2E1 in rat brain. Alcohol and Alcoholism 28 (Suppl 1B):69-75, 1993.
12. Drury AN, Szentgyörgyi A. The physiological activity of adenosine compounds with special reference to their action upon the mammalian heart. J Physiol 68:213-237, 1929.
13. Daly JW. Adenosine receptors characterization with radioactive ligands. In: Daly JW, Kuroda Y, Phillis JW, Shimizu H, Ui MI, Eds. Physiology and Pharmacology of Adenosine Derivatives. New York: Raven Press, pp59-69, 1983.
14. Gordon JL, Extracellular ATP: Effects, sources and fate. Biochem J 233:309-319, 1986.
15. Formento ML, Borsa M, Zoni G. Steroidogenic effect of adenosine in the rat. Pharmacol Res Commun 7:247-257, 1975.
16. Scaccianoce S, Navarra D, Di Sciullo A, Angelucci L, Endroczi E. Adenosine and pituitary-adrenocortical axis activity in the rat. Neuroendocrinology 50:464-468, 1989.
17. Gerlach E, Becker BF, Nees S. Formation of adenosine by vascular endothelium: A homeostatic and antithrombotic mechanism? In: Gerlach E, Becker B, Ed. Topics and Perspectives in Adenosine Research: Proceedings of the 3rd International Symposium on Adenosine. Springer Verlag: Munich, Germany, pp309-320, 1987.
18. Szabó J, Kósa E, Tóth IE, Bruckner G. Effect of adenosine and its metabolites on the hypothalamo-pituitary-adrenal axis. J Nutr Biochem 6:334-339, 1995.
19. Szabó J, Kósa E, Bruckner G. Time effect of ADP, AMP, adenosine, urate, and allantoin on plasma corticosterone and ACTH concentration in rats. FASEB J 9:A941, 1995.
20. Puig JG, Fox IH. Ethanol-induced activation of adenine turnover: Evidence for a role of acetate. J Clin Invest 74:936-941, 1984.
21. Nagy LE. Ethanol metabolism and inhibition of nucleoside uptake lead to increased extracellular adenosine in hepatocytes. Am J Physiol 262:C1175-C1180, 1992.
22. Rappay G, Gyévay A, Kondics L, Stark E. Growth and fine structure of monolayers derived from adult rat adenohypophyseal cell suspension. In Vitro 8:301-306, 1973.
23. Elion B. Biochemistry and pharmacology of purine analogues. Fed Proc 26:898-904, 1967.
24. Loo TL, Luce JK, Sullivan MP, Frei E. Clinical pharmacologie observations on 6-mercaptopurine and 6-methylthiopurine ribonucleoside. Clin Pharmacol Ther 9:180-194, 1968.
25. Leleiko NS, Martin BA, Walsh M, Kazlow P, Rabinowitz S, and Sterling K. Tissue-specific gene expression results from a purine- and pyrimidine-free diet and 6-mercaptopurine in rat small intestine and colon. Gastroenterology 93:1014-1020, 1987.
26. Wu TW, Zeng JW, Carey D. Purpurogallin - a natural and effective hepatoprotector in vitro and in vivo. Biochem Cell Biol 69:747-750, 1991.
27. Sheu SY, Lai CH, Chiang HC. Inhibition of xanthine oxidase by purpurogallin and silymarin group. Anticancer Res 18:263-268, 1968.
28. Rivier C, Lee S. Acute alcohol administration stimulates the activity of hypothalamic neurons that express corticotropin-releasing factor and vasopressin. Brain Res 726:1-10, 1996.
29. Brannan TS, Maker HS, Raes IP. Regional distribution of catalase in the adult rat brain. J Neurochem 36:307-309, 1981.
30. 2 system. Biochem Pharmacol 44:93-98, 1992.
31. Anand-Srivastava MB, Cantin M, Gutkowska J. Adenosine regulates the release of adrenocorticotrophic hormone (ACTH) from cultured pituitary cells. Mol Cell Biochem 89:21-28, 1989.
32. Masson S, Desmoulin F, Sciaky M, Cozzone PJ. Catabolism of adenine nucleotides and its relation with intracellular phosphorylated metabolite concentration during ethanol oxidation in perfused rat liver. Biochemistry 32:1025-1031, 1993.
33. Dendorfer A, Lauk S, Schaff A, Ness S. New insight to the myocardial adenosine formation. In: Gerlach E, Becker B, Eds. Topics and Perspectives in Adenosine Research: Proceedings of the 3rd International Symposium on Adenosine. Springer Verlag: Munich, Germany, pp170-187, 1986.
34. Möser GH, Schrader J, Deussen A. Turnover of adenosine in plasma of human and dog blood. Am J Physiol 256:C799-C806, 1989.
35. Williamson JR, Scholz R, Browning ET, Thurma RG, Fukami MH. Metabolic effects of ethanol in perfused rat liver. J Biol Chem 244:5044-5054, 1969.
36. Suokas A, Forsander O, Lindros K. Distribution and utilization of alcohol-derived acetate in the rat. J Stud Alcohol 45:381-385, 1984.
37. Sumi T, Umeda Y. Hyperuricemia in the rat following hypothalamic stimulation. Life Sci 21:1675-1678, 1977.