pH-dependent association of SN-38 with lipid bilayers of a novel liposomal formulation

International Journal of Pharmaceutics

Volumn 299, Issue 1-2, 2005, Pages 92-99

  Peikov, Viktor ^a   Ugwu, Sydney ^a   Parmar, Manjeet ^a   Zhang, Allen ^a   Ahmad, Imran ^a  

^a NeoPharm Inc   (United States)

Author keywords

Anisotropy; Bilayer; Fluorescence; Interaction; Liposomes; Lyophilization; SN 38

Indexed keywords

1,6 DIPHENYL 1,3,5 HEXATRIENE; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; BUFFER; FLUORINE; LIPOSOME; PLACEBO; TOLUENE DERIVATIVE;

ANISOTROPY; ARTICLE; DRUG FORMULATION; EMULSION; FLUORESCENCE POLARIZATION; FREEZE DRYING; GEL FILTRATION CHROMATOGRAPHY; HYDRATION; HYDROPHILICITY; HYDROPHOBICITY; LIPID BILAYER; METABOLITE; MOLECULAR PROBE; PARTITION COEFFICIENT; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; CARDIOLIPINS; CHOLESTEROL; CHROMATOGRAPHY, GEL; DIPHENYLHEXATRIENE; DNA TOPOISOMERASES, TYPE I; FLUORESCENCE POLARIZATION; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; HYDROPHOBICITY; LIPID BILAYERS; LIPOSOMES; PARTICLE SIZE; PHOSPHATIDYLCHOLINES; TEMPERATURE;

EID: 21844480086     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2005.04.028     Document Type: Article

References (22)

1. S.V. Balasubramanian, and R.M. Straubinger Taxol-lipid interactions: taxol-dependent effects on the physical properties of model membranes Biochemistry 33 1994 8941 8947
2. V. Ben-Yashar, and Y. Barenholz The interaction of cholesterol and cholest-4-en-3-one with dipalmitoylphosphatidylcholine. Comparison based on the use of three fluorophores Biochim. Biophys. Acta 985 1989 271 278
3. C. Bernsdorff, R. Reszka, and R. Winter Interaction of the anticancer agent Taxol™ (paclitaxel) with phospholipid bilayers J. Biomed. Mater. Res. 46 1999 141 149
4. C. Bernsdorff, A. Wolf, R. Winter, and E. Gratton Effect of hydrostatic pressure on water penetration and rotational dynamics in phospholipid- cholesterol bilayers Biophys. J. 72 1997 1264 1277
5. T.G. Burke, and X. Gao Stabilization of topotecan in low pH liposomes composed of distearoylphosphatidilcholine J. Pharm. Sci. 83 1994 967 969
6. T.G. Burke, and Z. Mi Ethyl substitution at the 7 position extends the half-life of 10-hydroxycamptothecin in the presence of human serum albumin J. Med. Chem. 36 1993 2580 2582
7. T.G. Burke, A.K. Mishra, M.C. Wani, and M.E. Wall Lipid bilayer partitioning and stability of camptothecin drugs Biochemistry 32 1993 5352 5364
8. T.G. Burke, A.E. Staubus, A.K. Mishra, and H. Malak Liposomal stabilization of camptothecin's lactone ring J. Am. Chem. Soc. 114 1992 8318 8319
9. R.B. Campbell, S.V. Balasubramanian, and R.M. Straubinger Influence of cationic lipids on the stability and membrane properties of paclitaxel- containing liposomes J. Pharm. Sci. 90 2001 1091 1105
10. - → AgBr J. Phys. Chem. B 102 1998 9319 9322
11. N.M. Correa, H. Zhang, and Z.A. Schelly Preparation of AgBr quantum dots via electroporation of vesicles J. Am. Chem. Soc. 122 2000 6432 6434
12. N. Kaneda, Y. Hosokawa, T. Yokokura, and S. Awazu Plasma pharmacokinetics of 7-ethyl-10-hydroxycamptothecin (SN-38) after intravenous administration of SN-38 and irinotecan (CPT-11) to rats Biol. Pharm. Bull. 20 1997 992 996
13. B.R. Lentz Membrane "fluidity" as detected by diphenylhexatriene probes Chem. Phys. Lipids 50 1989 171 190
14. B.R. Lentz, Y. Barenholz, and T.E. Thompson Fluorescence depolarization studies of phase transitions and fluidity in phospholipid bilayers. 1. Single component phosphatidylcholine liposomes Biochemistry 15 1976 4521 4528
15. B.R. Lentz, Y. Barenholz, and T.E. Thompson Fluorescence depolarization studies of phase transitions and fluidity in phospholipid bilayers. 2. Two-component phosphatidylcholine liposomes Biochemistry 15 1976 4529 4537
16. B.R. Lentz, B.M. Moore, and D.A. Barrow Light-scattering effects in the measurement of membrane microviscosity with diphenylhexatriene Biophys. J. 25 1979 489 494
17. B.J. Litman, and Y. Barenholz Fluorescence probe: diphenylhexatriene Meth. Enzymol. 81 1982 678 685
18. Z. Mi, and T.G. Burke Marked interspecies variations concerning the interactions of camptothecin with serum albumins: a frequency-domain fluorescence spectroscopic study Biochemistry 33 1994 12540 12545
19. H. Pottel, W. van der Meer, and W. Herreman Correlation between the order parameter and the steady-state fluorescence anisotropy of l,6-diphenyl-l,3,5- hexatriene and an evaluation of membrane fluidity Biochim. Biophys. Acta 730 1983 181 186
20. M. Shinitzky, and Y. Barenholz Fluidity parameters of lipid regions determined by fluorescence polarization Biochim. Biophys. Acta 515 1978 367 394
21. R.M. Wadkins, P.M. Potter, B. Vladu, J. Marty, G. Mangold, S. Weitman, G. Manikumar, M.C. Wani, M.E. Wall, and D.D. von Hoff Water soluble 20(S)-glycinate ester of 10,11-methylenedioxycamptothecins are highly active against human breast cancer xenografts Cancer Res. 59 1999 3424 3428
22. A. Zhang, T. Xuan, M. Parmar, L. Ma, S. Ugwu, S. Ali, and I. Ahmad Development and characterization of a novel liposome-based formulation of SN-38 Int. J. Pharm. 270 2004 93 107