Response to continuous and pulsatile PTH dosing: A mathematical model for parathyroid hormone receptor kinetics

Bone

Volumn 37, Issue 2, 2005, Pages 159-169

  Potter, Laura K ^a   Greller, Larry D ^a,b   Cho, Carolyn R ^a,b   Nuttall, Mark E ^a,c   Stroup, George B ^a   Suva, Larry J ^a,d   Tobin, Frank L ^a  

^a GLAXOSMITHKLINE   (United States)

^b Biosystemix Ltd   (Canada)

^c CENTOCOR INC   (United States)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Mathematical model; Osteoporosis; Parathyroid hormone; Parathyroid hormone receptor; Receptor kinetics

Indexed keywords

LIGAND; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR 1;

ARTICLE; BIOSYNTHESIS; DOSE RESPONSE; DRUG APPROVAL; DRUG EFFECT; DRUG TARGETING; FOOD AND DRUG ADMINISTRATION; HUMAN; KINETICS; MATHEMATICAL MODEL; NONHUMAN; OSSIFICATION; OSTEOLYSIS; POSTMENOPAUSE OSTEOPOROSIS; PREDICTION;

ANIMALS; BONE RESORPTION; HUMANS; KINETICS; MODELS, BIOLOGICAL; PARATHYROID HORMONE; RECEPTOR, PARATHYROID HORMONE, TYPE 1; SIGNAL TRANSDUCTION;

EID: 21844477031     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2005.04.011     Document Type: Article

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