Quantifying molecular specificity of αvβ3 integrin-targeted optical contrast agents with dynamic optical imaging

Journal of Biomedical Optics

Volumn 10, Issue 3, 2005, Pages

  Gurfinkel, Michael ^a   Ke, Shi ^b   Wang, Wei ^b   Li, Chun ^b   Sevick Muraca, Eva M ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Cancer; Fluorescence; Integrin; Molecular imaging; Pharmacokinetics; Xenograft

Indexed keywords

CELLS; CHARGE COUPLED DEVICES; DISEASES; FLUORESCENCE; IMAGE PROCESSING; MATHEMATICAL MODELS; MOLECULAR BIOLOGY; PHARMACOKINETICS; SYNTHESIS (CHEMICAL); TISSUE; TUMORS;

CELL ADHESION; INTEGRIN; MOLECULAR IMAGING; XENOGRAFT;

CARCINOGENS;

CARBOCYANINE; CONTRAST MEDIUM; CY5.5 CYANINE DYE; DIAGNOSTIC AGENT; TUMOR MARKER; TUMOR PROTEIN; VITRONECTIN RECEPTOR;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; COMPUTER ASSISTED DIAGNOSIS; DRUG DELIVERY SYSTEM; EVALUATION STUDY; FEMALE; FLUORESCENCE MICROSCOPY; HUMAN; IMAGE ENHANCEMENT; KAPOSI SARCOMA; KINETICS; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; MOUSE; NUDE MOUSE; PATHOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION;

ANIMALS; CARBOCYANINES; CONTRAST MEDIA; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; INTEGRIN ALPHAVBETA3; KINETICS; METABOLIC CLEARANCE RATE; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; REPRODUCIBILITY OF RESULTS; SARCOMA, KAPOSI; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; TUMOR MARKERS, BIOLOGICAL;

EID: 21844469333     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.1924696     Document Type: Article

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