The role of extracellular potassium in the epileptogenic transformation of recurrent GABAergic inhibition

Epilepsia

Volumn 46, Issue SUPPL. 5, 2005, Pages 64-71

  Id Bihi, Rachid ^a   Jefferys, John G R ^a   Vreugdenhil, Martin ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Burst firing; CA1; Epilepsy; GABA; Hippocampus; Potassium

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 4 AMINOBUTYRIC ACID; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; POTASSIUM ION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN ELECTROPHYSIOLOGY; CONFERENCE PAPER; CONTROLLED STUDY; EPILEPSY; EPILEPTOGENESIS; HIPPOCAMPUS; MALE; MEMBRANE POTENTIAL; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

EID: 21844468734     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2005.01011.x     Document Type: Conference Paper

References (47)

1. Traub RD, Miles R, Jefferys JGR. Synaptic and intrinsic conductances shape picrotoxin-induced synchronized after-discharges in the guinea-pig hippocampal slice. J Physiol (Lond) 1993;461:525-47.
2. Babb TL, Pretorius JK, Kupfer WR, et al. Glutamate decarboxylase- immunoreactive neurons are preserved in human epileptic hippocampus. J Neurosci 1989;9:2562-74.
3. Cossart R, Dinoncourt C, Hirsch JC, et al. Dendritic but not somatic GABAergic inhibition is decreased in experimental epilepsy. Nat Neurosci 2001;4:52-62.
4. Burg M, Heinemann U, Schmitz D. Neuroactive steroids induce GABA(A) receptor-mediated depolarizing postsynaptic potentials in hippocampal CA1 pyramidal cells of the rat. Eur J Neurosci 1998;10:2880-6.
5. Bracci E, Vreugdenhii M, Hack SP, et al. On the synchronising mechanisms of tetanically-induced hippocampal oscillations. J Neurosci 1999;19:8104-13.
6. A receptor-mediated oscillations. J Neurosci 2000;20:6800-29.
7. Pena F, Tapia R. Seizures and neurodegeneration induced by 4-aminopyridine in rat hippocampus in vivo: role of glutamate- and GABA-mediated neurotransmission and of ion channels. Neuroscience 2000;101:547-61.
8. A receptor channel function in the nervous system. Prog Neurobiol 1994;42:489-537.
9. A receptors. Science 1995;269:977-81.
10. Cohen I, Navarro V, Clemenceau S, et al. On the origin of interictal activity in human temporal lobe epilepsy in vitro. Science 2002;298:1418-21.
11. Perreault P, Avoli M. 4-Aminopyridine-induced epileptiform activity and a GABA-mediated long-lasting depolarization in the rat hippocampus. J Neurosci 1992;12:104-15.
12. Deisz RA. Cellular mechanisms of pharmacoresistance in slices from epilepsy surgery. Novartis Found Symp 2002;243:186-99.
13. Perez Velazquez JL, Carlen PL. Synchronization of GABAergic interneuronal networks during seizure-like activity in the rat horizontal hippocampal slice. Eur J Neurosci 1999;11:4110-8.
14. Id Bihi R, Vreugdenhil M, Jefferys JGR. Depolarising GABA triggers epileptiform activity in the isolated CA1 region of the adult rat hippocampus. FENS Abstr 2002;1:A187.16.
15. Fujiwara-Tsukamoto Y, Isomura Y, Nambu A, et al. Excitatory GABA input directly drives seizure-like rhythmic synchronisation in mature hippocampal CA1 pyramidal cells. Neuroscience 2003;119:265-75.
16. - accumulation responsible for depolarizing GABAergic responses in mature hippocampal neurons. J Neurophysiol 2003;90:2751-6.
17. - accumulation and depletion in cultured rat midbrain neurons. J Neurosci 1999;19:4695-704.
18. Cl- in hippocampal CA3 neurons. J Neurophysiol 1989;61:512-23.
19. Bikson M, Id Bihi R, Vreugdenhil M, et al. Quinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro. Neuroscience 2002;115:251-61.
20. Tamamaki N, Abe K, Nojyo Y. Columnar organization in the subiculum formed by axon branches originating from single CA1 pyramidal neurons in the rat hippocampus. Brain Res 1987;412:156-60.
21. Deuchars J, Thomson AM. CA1 pyramid-pyramid connections in rat hippocampus in vitro: dual intracellular recordings with biocytin filling. Neuroscience 1996;74:1009-18.
22. A receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice. J Neurosci 2000;20:7531-8.
23. Smirnov S, Paalasmaa P, Uusisaari M, et al. Pharmacological isolation of the synaptic and nonsynaptic components of the GABA-mediated biphasic response in rat CA1 hippocampal pyramidal cells. J Neurosci 1999;19:9252-60.
24. + channels by quinidine. FEBS Lett 1995;375:193-6.
25. + channels in mouse pancreatic beta-cells. J Physiol (Lond) 1990;423:311-25.
26. Somjen GG, Giacchino JL. Potassium and calcium concentrations in interstitial fluid of hippocampal formation during paroxysmal responses. J Neurophysiol 1985;53:1098-108.
27. Avoli M, D'Antuono M, Louvel J, et al. Network and pharmacological mechanisms leading to epileptiform synchronization in the limbic system in vitro. Prog Neurobiol 2002;68:167-207.
28. Traynelis ST, Dingledine R. Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice. J Neurophysiol 1988;1:259-76.
29. Grunze HC, Rainnie DG, Hasselmo ME, et al. NMDA-dependent modulation of CA1 local circuit inhibition. J Neurosci 1996;16:2034-43.
30. - accumulation does not account for the depolarizing phase of the synaptic GABA response in hippocampal pyramidal cells. J Neurophysiol 1999;82:768-77.
31. + transient. J Neurosci 1997;17:7662-72.
32. Michelson HB, Wong RKS. Synchronization of inhibitory neurons in the guinea-pig hippocampus in vitro. J Physiol (Lond) 1994;477:35-45.
33. DeFazio RA, Keros S, Quick MW, et al. Potassium-coupled chloride cotransport controls intracellular chloride in rat neocortical pyramidal neurons. J Neurosci 2000;20:8069-76.
34. Ariav G, Polsky A, Schiller J. Submillisecond precision of the input-output transformation function mediated by fast sodium dendritic spikes in basal dendrites of CA1 pyramidal neurons. J Neurosci 2003;23:7750-8.
35. Hoffman DA, Magee JC, Colbert CM, et al. K channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature 1997;387:869-75.
36. Xiong ZQ, Stringer JL. Sodium pump activity, not glial spatial buffering, clears potassium after epileptiform activity induced in the dentate gyrus. J Neurophysiol 2000;83:1443-51.
37. - transport. J Physiol (Lond) 1999;519:693-712.
38. Hara M, Inoue M, Yasukura T, et al. Uneven distribution of intracellular Cl- in rat hippocampal neurons. Neurosci Lett 1992; 143:135-8.
39. Gulledge AT, Stuart GJ. Excitatory actions of GABA in the cortex. Neuron 2003;37:299-309.
40. Colling SB, Stanford IM, Traub RD, et al. Limbic gamma rhythms, I: phase-locked oscillations in hippocampal CA1 and subiculum. J Neurophysiol 1998;80:155-61.
41. Id Bihi R, Vreugdenhil M, Jefferys JGR. Role of extracellular potassium and recurrent excitation in the generation of epileptiform activity in hippocampal area CA1. 6th IBRO Congress abstract CD, 1054. 2003.
42. Patrylo PR, Spencer DD, Williamson A. GABA uptake and heterotransport are impaired in the dentate gyrus of epileptic rats and humans with temporal lobe sclerosis. J Neurophysiol 2001;85:1533-42.
43. Woo NS, Lu J, England R, et al. Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene. Hippocampus 2002;12:258-68.
44. Okabe A, Yokokura M, Toyoda H, et al. Changes in chloride homeostasis-regulating gene expressions in the rat hippocampus following amygdala kindling. Brain Res 2003;990:221-6.
45. Anderson WR, Franck JE, Stahl WL, et al. K-ATPase is decreased in hippocampus of kainate-lesioned rats. Epilepsy Res 1994;17:221-31.
46. o in human epileptic non-sclerotic and sclerotic hippocampal area CA1. Eur J Neurosci 2000;12:2039-48.
47. Gabriel S, Eilers A, Kivi A, et al. Effects of barium on stimulus induced changes in extracellular potassium concentration in area CA1 of hippocampal slices from normal and pilocarpine-treated epileptic rats. Neurosci Lett 1998;242:9-12.