Specific induction of neurons and Schwann cells from bone marrow stromal cells and application to neurodegenerative diseases

Neurological Surgery

Volumn 33, Issue 7, 2005, Pages 645-649

  Dezawa, Mari ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Mesenchyme cell; Neurodegeneractive disease; Parkinson's disease; Regenerative medicine; Spinal cord injury; Transdifferentiation

Indexed keywords

BONE MARROW CELL; BRAIN ISCHEMIA; DEGENERATIVE DISEASE; HUMAN; HUMAN CELL; NERVE CELL; NERVE CELL DIFFERENTIATION; PARKINSON DISEASE; PERIPHERAL NERVE INJURY; REVIEW; SCHWANN CELL; SPINAL CORD INJURY; STROMA CELL;

BONE MARROW CELLS; CELL DIFFERENTIATION; HUMANS; NERVE REGENERATION; NEURODEGENERATIVE DISEASES; NEURONS; PARKINSON DISEASE; SCHWANN CELLS; SPINAL CORD INJURIES; STROMAL CELLS;

EID: 21844461074     PISSN: 03012603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (22)

1. Borlongan CV, Lind JG, Dillon-Carter O, Yu G, Hadman M, Cheng C, Carroll J, and Hess DC: Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats. Brain Res 1010: 108-116, 2004
2. Brazelton TR, Rossi FM, Keshet GI, Blau HM: From marrow to brain: expression of neuronal phenotypes in adult mice. Science 290: 1775-1779, 2000
3. Dezawa M, Takahashi I, Esaki M, Takano M, Sawada H: Sciatic nerve regeneration in rats induced by transplantation of in vitro differentiated bone-marrow stromal cells. Eur J Neurosci 14: 1771-1776, 2001
4. Dezawa M, Kanno H, Hoshino M, Cho H, Matsumoto N, Itokazu Y, Tajima N, Yamada H, Sawada H, Ishikawa, H., et al: Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation. J Clin Invest 113: 1701-1710, 2004
5. Eglitis MA, Mezey E: Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice. Proc Natl Acad Sci U S A 94: 4080-4085, 1997
6. Haas S, Weidner N, Winkler J: Adult stem cell therapy in stroke. Curr Opin Neurol 18: 59-64, 2005
7. Hofstetter CP, Schwarz EJ, Hess D, Widenfalk J, El Manira A, Prockop DJ, Olson L: Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery. Proc Natl Acad Sci U S A 99:2199-2204, 2002
8. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M, Lenvik T, Lund T, Blackstad M, et al: Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418: 41-49, 2002
9. Kamada T, Koda M, Dezawa M, Yoshinaga K, Hashimoto M, Koshizuka S, Nishio Y, Moriya H, Yamazaki M: Transplantation of bone marrow stromal cell-derived Schwann cells promotes axonal regeneration and functional recovery after complete transection of adult rat spinal cord. J Neuropathol Exp Neurol 64: 37-45, 2005
10. Kawasaki H, Mizuseki K, Nishikawa S, Kaneko S, Kuwana Y, Nakanishi S, Nishikawa SI, Sasai Y: Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 28: 31-40, 2000
11. Kohyama J, Abe H, Shimazaki T, Koizumi A, Nakashima K, Gojo S, Taga T, Okano H, Hata J, Umezawa A: Brain from bone: Efficient "meta- differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent. Differentiation 68: 235-244, 2001
12. McBride JL, Behrstock SP, Chen EY, Jakel RJ, Siegel I, Svendsen CN, Kordower JH: Human neural stem cell transplants improve motor function in a rat model of Huntington's disease. J Comp Neurol 475: 211-219, 2004
13. Mimura T, Dezawa M, Kanno H, Sawada H, Yamamoto I: Peripheral nerve regeneration by transplantation of bone marrow stromal cell-derived Schwann cells in adult rats. J Neurosurg 101: 806-812, 2004
14. Morshead CM, Reynolds BA, Craig CG, McBurney MW, Staines WA, Morassutti D, Weiss S, van der Kooy D: Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells. Neuron 13: 1071-1082, 1994
15. Okano H, Ogawa Y, Nakamura M, Kaneko S, Iwanami A, Toyama Y: Transplantation of neural stem cells into the spinal cord after injury. Semin Cell Dev Biol 14: 191-198, 2003
16. Prockop DJ: Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276: 71-74, 1997
17. Pittenger MF, Mosca JD, McIntosh KR: Human mesenchymal stem cells: progenitor cells for cartilage, bone, fat and stroma. Curr Top Microbiol Immunol 251: 3-11, 2000
18. Sanchez-Ramos J, Song S, Cardozo-Pelaez F, Hazzi C, Stedeford T, Willing A, Freeman TB, Saporta S, Janssen W, Patel N, et al: Adult bone marrow stromal cells differentiate into neural cells in vitro. Exp Neurol 164: 247-256, 2000
19. Terada N, Hamazaki T, Oka M, Hoki M, Mastalerz DM, Nakano Y, Meyer EM, Morel L, Petersen BE, Scott EW: Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 416: 542-545, 2002
20. Weinmaster G, Roberts VJ, and Lemke G: A homolog of Drosophila Notch expressed during mammalian development. Development 113: 199-205, 1991
21. Woodbury D, Schwarz EJ, Prockop DJ, Black, IB: Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 61: 364-370, 2000
22. Zhang RL, Zhang ZG, Zhang L, Chopp M Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia. Neuroscience 105: 33-41, 2001