The presence of benign prostatic glandular tissue at surgical margins does not predict PSA recurrence

Journal of Clinical Pathology

Volumn 58, Issue 7, 2005, Pages 725-728

  Kernek, K M ^b   Koch, M O ^b   Daggy, J K ^b   Juliar, B E ^b   Cheng, L ^a,b  

^a INDIANA UNIVERSITY MEDICAL CENTER   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; AGE; AGED; ARTICLE; CANCER INVASION; CANCER RECURRENCE; CANCER STAGING; CONTROLLED STUDY; GLEASON SCORE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; ORGAN WEIGHT; OUTCOMES RESEARCH; PREDICTION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATE WEIGHT; PROSTATECTOMY; PROTEIN BLOOD LEVEL; TISSUE DISTRIBUTION; TISSUE SECTION; TISSUE STRUCTURE; TUMOR VOLUME;

ADULT; AGE FACTORS; AGED; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; POSTOPERATIVE PERIOD; PROGNOSIS; PROSTATE; PROSTATE-SPECIFIC ANTIGEN; PROSTATECTOMY; PROSTATIC NEOPLASMS; RECURRENCE;

EID: 21844451939     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.2004.024182     Document Type: Article

References (20)

1. Pound CR, Partin AW, Eisenberger MA, et al. Natural history of progression after PSA elevation following radical prostatectomy. JAMA 1999;281:1591-7.
2. Frazier HA, Robertson JE, Humphrey PA, et al. Is prostate specific antigen of clinical importance in evaluating outcome after radical prostatectomy? J Urol 1993;149:516-18.
3. Cheng L, Darson MF, Bergstralh EJ, et al. Correlation of margin status and extraprostatic extension with progression of prostate carcinoma. Cancer 1999;86:1775-82.
4. Cheng L, Slezak J, Bergstralh EJ, et al. Preoperative prediction of surgical margin status in prostate cancer patients treated by radical prostatectomy. J Clin Oncol 2000;18:2862-8.
5. Emerson RE, Koch MO, Daggy J, et al. Closest distance between tumor and resection margin in radical prostatectomy specimens: lack of prognostic significance. Am J Surg Pathol 2005;29:225-9.
6. Eichelberger LE, Cheng L. Does pT2b prostate carcinoma exist? Critical appraisal of the 2002 TNM classification of prostate carcinoma. Cancer 2004;100:2573-6.
7. Poulos CK, Daggy JK, Cheng L. Prostate needle biopsies: multiple variables are predictive of final tumor volume in radical prostatectomy specimens. Cancer 2004;101:527-32.
8. Poulos CK, Koch MO, Eble JN, et al. Bladder neck invasion is an independent predictor of prostate-specific antigen recurrence. Cancer 2004;101:1563-8.
9. Hong H, Koch MO, Foster RS, et al. Anatomic distribution of periprostatic adipose tissue: a mapping study of 100 radical prostatectomy specimens. Cancer 2003;97:1639-43.
10. Gleason DF, Mellinger GT. Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. Veterans' administration cooperative urologic research group. J Urol 1974;111:58-64.
11. Fleming ID, Cooper JS, Henson DE, et al. AJCC cancer staging manual. Philadelphia: Lippincott Raven, 1997.
12. Humphrey PA, Vollmer RT. Intraglandular tumor extent and prognosis in prostatic carcinoma: application of a grid method to prostatectomy specimens. Hum Pathol 1990;21:799-804.
13. Eichelberger LE, Koch MO, Daggy JK, et al. Predicting tumor volume in radical prostatectomy specimens from patients with prostate cancer. Am J Clin Pathol 2003;120:380-91.
14. Koch MO, Foster RS, Bell B, et al. Characterization and predictors of prostate specific antigen progression rates after radical retropubic prostatectomy. J Urol 2000;164:749-53.
15. Babaian RJ, Troncoso P, Bhadkamkar VA, et al. Analysis of clinicopathologic factors predicting outcome after radical prostatectomy. Cancer 2001;91:1414-22.
16. Shah R, Bassily N, Wei J, et al. Benign prostatic glands at surgical margins of radical prostatectomy specimens: frequency and associated risk factors. Urology 2000;56:721-5.
17. Boccon-Gibod L, Ravery V, Vordos D, et al. Radical prostatectomy for prostate cancer: the perineal approach increases the risk of surgically induced positive margins and capsular incisions. J Urol 1998;160:1383-5.
18. Allsbrook WC, Wade ZK, Scott PA, et al. Benign prostatic epithelium is commonly present at the surgical margins of radical prostatectomy. Mod Pathol 2002;15:632A.
19. Ravery V. The significance of recurrent PSA after radical prostatectomy: benign versus malignant sources. Semin Urol Oncol 1999;17:127-9.
20. Barocas DA, Man M, Epstein JI, et al. Does capsular incision at radical retrapubic prostatectomy affect disease-free survival in otherwise organ-confined prostate cancer? Urology 2001;58:746-51.