The effects of self-absorption and detection geometry on fluorescence intensity and decay lifetime

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 5702, Issue , 2005, Pages 123-134

  Cormier, Jean François ^a   Fortin, Michel ^a   Fréchette, Julie ^a   Noiseux, Isabelle ^a   Vernon, Marcia L ^a   Long, William ^b  

^a INO   (Canada)

^b Chemical Computing Group   (Canada)

Author keywords

Fluorescence concentration effects; Fluorescence lifetime; Fluorescence self absorption; TCSPC; Time Correlated Single Photon Counting

Indexed keywords

LIGHT EMISSION; MONTE CARLO METHODS; OPTICAL IMAGE STORAGE; PHOTONS; PROTEINS; SCATTERING; TISSUE;

FLUORESCENCE CONCENTRATION EFFECTS; FLUORESCENCE LIFETIME; FLUORESCENCE SELF-ABSORPTION; TIME-CORRELATED SINGLE PHOTON COUNTING (TCSPC);

FLUORESCENCE;

EID: 21844451442     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.591026     Document Type: Conference Paper

References (12)

1. P. R. Hammond, "Self absorption of molecular fluorescence, the design of equipment for measurement of fluorescence decay, and the decay times of some laser dyes," J. Chem. Phys., pp. 3384, 1979.
2. J. Baumann, G. Calzaferri, and T. Hugentobler, "Self-absorption and re-emission in wavelength-dependent fluorescence decay," Chemical Physics Lett., pp. 66-72, 1985.
3. G. Calzaferri and T. Hugentobler, "Time-resolved fluorescence spectra derived from multiple frequency phase fluorimetry," Chem. Phys. lett, vol. 121, pp. 147-153, 1985.
4. S. A. Ahmed, Z.-W. Zang, K. M. Yoo, M. A. Ali, and R. R. Alfano, "Effect of multiple light scattering and self-absorption on the fluorescence and excitation spectra of dyes in random media," Appl. Opt., vol. 33, pp. 2746-2750, 1994.
5. S. Avrillier, E. Tinet, D. Ettori, J.-M. Tualle, and B. Gelebart, "Influence of the emissin-reception geometry in laser-induced fluorescence spectra from turbid media," Appl. Opt., vol. 37, pp. 2781-2787, 1998.
6. M. S. Patterson and B. W. pogue, "Mathematical model for time-resolved and frequency-domain fluorescence spectroscopy in biological tissues," Appl. Opt., vol. 33, pp. 1963-1974, 1994.
7. A. E. Cerussi, J. S. Maier, S. Fantini, M. A. Franceschini, W. W. Mantulin, and E. Gratton, "Experimental verification of a theory for the time-resolved fluorescence spectroscopy of thick tissues," Appl. Opt., vol. 36, pp. 116-124, 1997.
8. S. Kao, A. N. Asanov, and P. B. Oldham, "A comparison of fluorescence inner-filter effects for different cell configurations," Instr. Sci. Tech., vol. 26, pp. 375-387, 1998.
9. A. Bouchard, J. Fréchette, W. F. Long, M. Vernon, J.-F. Cormier, R. Vallée, A. A. Mafu, and M. Lemay, "Non-contact characterization of bacteria by time-resolved fluorescence," presented at Photonics West 2004, Biomedical Vibrational Spectroscopy and Biohazard Detection Technologies, San Jose, CA, 2004, Paper 5321-41.
10. Oregon Medical Laser Center web site: http://omlc.ogi.edu/spectra/ PhotochemCAD/html/index.html
11. J. R. Lacowitz, Principle of Fluorescence Spectroscopy, 2nd ed. New York: Kluwer Academic, 1999.
12. Y. Painchaud, A. Mailloux, M. Morin, S. Verreault, and P. Beaudry, "Time-domain optical imaging: discrimination between scattering and absorption," Appl. Opt., vol. 38, pp. 3686-3693, 1999.