'Fat burner' herb, usnic acid, induced acute hepatitis in A family [5]

Journal of Gastroenterology and Hepatology (Australia)

Volumn 20, Issue 7, 2005, Pages 1138-1139

  Hsu, Li Ming ^a   Huang, Yi Shin ^a   Chang, Full Young ^a   Lee, Shou Dong ^a  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

USNIC ACID;

ACUTE HEPATITIS; ADULT; ANAMNESIS; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; CASE REPORT; CLINICAL FEATURE; DIET SUPPLEMENTATION; FAMILY; FEMALE; HUMAN; LETTER; LIVER TOXICITY; PRIORITY JOURNAL; SOYBEAN; WEIGHT REDUCTION;

EID: 21844450250     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2005.03855.x     Document Type: Letter

References (5)

1. Favreau JT, Ryu ML, Braunstein G et al. Severe hepatotoxicity associated with the dietary supplement LipoKinetix. Ann. Intern. Med. 2002; 136: 590-5.
2. Durazo FA, Lassman C, Han SHB et al. Fulminant liver failure due to usnic acid for weight loss. Am. J. Gastroenterol. 2004; 99: 950-2.
3. Estes JD, Stolpman D, Olyaei A et al. High prevalence of potentially hepatotoxic herbal supplement use in patients with fulminant hepatic failure. Arch. Surg. 2003; 138: 852-5.
4. Han D, Matsumaru K, Rettori D, Kaplowitz N. Usnic acid-induced necrosis of cultured mouse hepatocytes: inhibition of mitochondrial function and oxidative stress. Biochem. Pharmacol. 2004; 67: 439-51.
5. Pramyothin P, Janthasoot W, Pongnimitprasert N, Phrukudom S, Ruangrungsi N. Hepatotoxic effect of (+) usnic acid from Usnea siamensis Wainio in rats, isolated rat hepatocytes and isolated rat liver mitochondria. J. Ethnopharmacol. 2004; 90: 381-7.