Stevens-Johnson syndrome associated with single high dose of lamotrigine in a patient taking valproate

Dermatology Online Journal

Volumn 11, Issue 1, 2005, Pages

  Famularo, Giuseppe ^a   De Simone, Claudio ^b   Minisola, Giovanni ^a  

^a SAN CAMILLO FORLANINI HOSPITAL   (Italy)

^b UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CEPHALOSPORIN DERIVATIVE; LAMOTRIGINE; PREDNISOLONE; PROTON PUMP INHIBITOR; VALPROIC ACID;

ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; HUMAN; LABORATORY TEST; MALE; RASH; STEVENS JOHNSON SYNDROME; TITRIMETRY; TONIC CLONIC SEIZURE;

EID: 21844447086     PISSN: 10872108     EISSN: 10872108     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Rzany B, Correia O, Kelly JP, Naldi L, Auquier A, Stern R. Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis during first weeks of antiepileptic therapy: a case-control study. Study Group of the International Case Control Study on Severe Cutaneous Adverse Reactions. Lancet 1999;354:1033-1034.
2. Messengill HS, Kustra RP, Messenheimer JA. Serious cutaneous reactions with antiepileptic drugs: adult and pediatric incidence estimates from registry and prescription data in Germany. Poster presentation at American Society of Health Systems Pharmacists Midyear Meeting, New Orleans, December 6-11, 2003.
3. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-245.
4. Yalcin B, Karaduman A. Stevens-Johnson syndrome associated with concomitant use of lamotrigine and valproic acid. J Am Acad Dermatol 2000;43:898-899.
5. Gidal BE, Sheth R, Parnell J, Maloney K, Sale M. Evaluation of VPA dose and concentration effects on lamotrigine pharmacokinetics: implications for conversion to lamotrigine monotherapy. Epilepsy Res 2003;57:85-93.