A chronic dysfunctional stress response can cause stroke by stimulating platelet activation, migraine, and hypertension

Medical Hypotheses

Volumn 65, Issue 3, 2005, Pages 542-545

  Eggers, A E ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL T TYPE; ETHOSUXIMIDE; ION CHANNEL; VALPROIC ACID; ZONISAMIDE;

ACUTE DISEASE; ARTICLE; BLOOD CLOTTING; BLOOD PRESSURE; BRAIN NERVE CELL; CELL FUNCTION; CELL NUCLEUS; CELL STIMULATION; DORSAL RAPHE NUCLEUS; DRUG EFFECT; HEADACHE; HYPERTENSION; MESENCEPHALON; MIGRAINE; PATHOGENESIS; PREDICTION; PRIORITY JOURNAL; PROPHYLAXIS; STRESS; STROKE; THROMBOCYTE ACTIVATION;

CEREBROVASCULAR ACCIDENT; CHRONIC DISEASE; HUMANS; HYPERTENSION; MIGRAINE DISORDERS; PLATELET ACTIVATION; STRESS;

EID: 21844443139     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2005.03.020     Document Type: Article

References (19)

1. M.J. Davies, and A. Thomas Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death N Engl J Med 310 1884 1137 1140
2. M.S. Pessin, R.C. Hinton, and K.R. Davis Mechanisms of acute carotid stroke Ann Neurol 6 1979 245 252
3. M. Britton, A. Carlsson, and U. DeFaire Blood pressure course in patients with acute stroke and matched controls Stroke 5 1986 861 864
4. K. Vestergaard, G. Andersen, M.N. Nielsen, and T.S. Jensen Headache in stroke Stroke 24 1993 1621 1624
5. A.E. Eggers Neurological theory of hypertension Med Hypotheses 60 2003 852 855
6. M. Wiehe, S.C. Fuchs, L.B. Moreira, R.S. Moraes, and F.D. Fuchs Migraine is more frequent in individuals with optimal and normal blood pressure: a population-based study J Hypertens 20 2002 1303 1306
7. K. Hagen, L.J. Stovner, L. Vatten, J. Holmen, J.-A. Swart, and G. Bovim Blood pressure and risk of headache: a prospective study of 22,685 adults in Norway J Neurol Neurosurg Psychiatry 72 2002 463 466
8. R.A. Davidoff Migraine: manifestations, pathogenesis, and management 2000 F.A. Davis Co. Philadelphia (PA) 172
9. G. D'Andrea, A. Cananzi, M. Toldo, S. Cortelazzo, and F. Ferro-Milone Platelet behavior in classic migraine: responsiveness to small doses of aspirin Throm Haemostas (Stuttgart) 49 1983 153
10. C. Manotti, R. Quintavilla, and G.C. Manzoni Platelet activation in migraine Throm Haemostas (Stuttgart) 50 1983 758
11. P.J. Koudstaal, G. Ciabattoni, and J. van Gijn Increased thromboxane biosynthesis in patients with acute cerebral ischemia Stroke 24 1993 219 223
12. F. van Kooten, G. Ciabattoni, C. Patrono, P.I.M. Schmitz, J. van Gijn, and J. Koudstaal Evidence for episodic platelet activation in acute ischemic stroke Stroke 25 1994 278 281
13. D.J. Fitzgerald, L. Roy, F. Catella, and G.A. Fitzgerald Platelet activation in unstable coronary disease N Engl J Med 315 1986 983 989
14. International Stroke Trial Collaborative Group The international stroke trial (IST): a randomised trial of aspirin, subcutaneous heparin, both or neither among 19,435 patients with acute ischaemic stroke Lancet 349 1997 1569 1581
15. J.P. Mohr, J.L.P. Thompson, and R.M. Lazar A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke N Engl J Med 345 2001 1444 1451
16. K.R. Merikangas, B.T. Fenton, S.H. Cheng, M.J. Stolar, and N. Risch Association between migraine and stroke in a large-scale epidemiological study of the United States Arch Neurol 54 1997 362 368
17. A.I. Scher, G.M. Terwindt, H.S.J. Picavet, W.M.M. Verschuren, M.D. Ferrari, and L.J. Launer Cardiovascular risk factors and migraine. The GEM population-based study Neurology 64 2005 614 620
18. 2+ conductance Synapse 1 1987 582 588
19. A.E. Eggers, and H. Moreno Suggestion for another anti-epileptic drug to use for migraine prophylaxis Headache 42 2002 696 697 Letter to the editor