Effect of the freezing conditions and microwave thawing power on the stability of cefuroxime in dextrose 5% infusion polyolefin bags at 4 °C

Annals of Pharmacotherapy

Volumn 39, Issue 7-8, 2005, Pages 1244-1248

  Hecq, Jean Daniel ^a   Boitquin, Laurence P ^a   Vanbeckbergen, Danielle F ^a   Jamart, Jacques ^a   Galanti, Laurence M ^a  

^a UNIVERSITY HOSPITAL OF MONT GODINNE   (Belgium)

Author keywords

Cefuroxime stability: freezing; Microwave thawing

Indexed keywords

CEFUROXIME; GLUCOSE; POLYOLEFIN;

ARTICLE; COLOR; DRUG SOLUTION; DRUG STABILITY; FREEZING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LOW TEMPERATURE; MICROWAVE RADIATION; PH; PRECIPITATION; PRIORITY JOURNAL; THAWING;

CEFUROXIME; CEPHALOSPORINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG PACKAGING; DRUG STABILITY; DRUG STORAGE; FREEZING; GLUCOSE; HYDROGEN-ION CONCENTRATION; INFUSION PUMPS; INJECTIONS; MICROWAVES; PHARMACEUTICAL SOLUTIONS; POWDERS; REFERENCE STANDARDS;

EID: 21744459566     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1E686     Document Type: Article

References (34)

1. Parfitt K. Martindale. The complete drug reference. 32nd ed. London: Pharmaceutical Press, 1999.
2. Koundalijan J. Setting up a CIVAS. In: Needle R, Sizer T. The CIVAS handbook. 1st ed. London: Pharmaceutical Press, 1998:1-5.
3. Vigneron J, Laurelli F, Phaypradith S, Perrin A, Hoffman MA, Hoffman M. [Freezing of solution for parenteral usage: advantage and disadvantage. Nine month's experience at the pharmacy of Hospital of Nancy] French. J Pharm Belg 1992;47:504-22.
4. Awang DVC, Graham KC. Microwave thawing of frozen drug solutions (letter). Am J Hosp Pharm 1987;44:2256.
5. Biaise N, Vigneron J, Perrin A, Noirez V, Hoffman MA, Hoffman M. Stability of refrigerated and frozen solutions of ondansetron HCl. Eur J Hosp Pharm 1994;4:12-3.
6. Elliot GT, McKenzie MW, Curry SH, Pieper JA, Quinn SL. Stability of cimetidine HCl in admixtures after microwave thawing. Am J Hosp Pharm 1983;40:1002-6.
7. Goerget S, Vigneron J, Blaise N, Perrin A, Hoffman MA, Hoffman M. Stability of refrigerated and frozen solutions of tropisetron in either polyvinyl chloride or polyolefin infusion bags. J Clin Pharm Ther 1997; 22:257-60.
8. Hilleman DK, McEvoy GK, Bailey RT, Reich J. Stability of cephapirin sodium admixture after freezing and conventional or microwave thaw techniques. Hosp Pharm 1984;19:202-12.
9. Holmes CJ, Ausman RK, Walter CW, Kundsin RB. Activity of antibiotic admixtures subjected to different freeze-thaw treatments. DICP 1980;14: 353-7.
10. Holmes CJ, Ausman RK, Kundsin RB, Walter CW. Effect of freezing and microwave thawing on the stability of six antibiotic admixtures in plastic bags. Am J Hosp Pharm 1982;39:104-8.
11. Kedzierewicz F, Finance C, Nicolas A, Dixneuf P, Hoffman M. Stability of parenteral ceftriaxone disodium solutions in frozen and liquid states: effect of freezing and microwave thawing. J Pharm Sci 1989;78:73-7.
12. Kirk B, Melia CD, Wilson JV, Sprake JM. Chemical stability of cyclophosphamide injection: the effect of low storage and microwave thawing. Br J Parenter Ther 1984;5:90-9.
13. Sanburg AL, Lyndon RC, Sunderland B. Effects of freezing, long term storage and microwave thawing on the stability of three antibiotics reconstituted in minibags. Aust J Hosp Pharm 1987;17:31-4.
14. Sewell GJ, Palmer AJ. The chemical and physical stability of three intravenous infusions subjected to frozen storage and microwave thawing. Int J Pharm 1991;72:57-63.
15. Stiles ML. Effect of microwave radiation on the stability of frozen cefoxitin sodium solution in plastic bags. Am J Hosp Pharm 1981;38:1743-5.
16. Trissel LA. Drug stability and compatibility issues in drug delivery. In: Trissel LA. Handbook on injectable drugs, 11th ed. Bethesda, MD: American Society of Health-System Pharmacists, 2001:XII-XVII.
17. Thiesen J, Kramer I. Physico-chemical stability of docetaxel premix solution and docetaxel infusion solutions in PVC bags and polyolefin containers. Pharm World Sci 1999;21:137-41.
18. Trissel LA, Pearson SD. Storage of lorazepam in three injectable solutions in polyvinyl chloride and polyolefin bags. Am J Hosp Pharm 1994;51:1825-6.
19. Norenberg JP, Achusim LE, Steel TH, Anderson TL. Stability of lorazepam in 0.9% sodium chloride stored in polyolefin bags. Am J Health Syst Pharm 2004;61:1039-41.
20. Zhang Y, Xu QA, Trissel LA, Gilbert DL, Martinez JF. Compatibility and stability of paclitaxel combined with cisplatin and with carboplatin in infusion solutions. Ann Pharmacother 1997;31:1465-70.
21. Trissel LA, Xu QA, Gilbert DL. Compatibility and stability of paclitaxel combined with doxonibicin hydrochloride in infusion solutions. Ann Pharmacother 1998;32:1013-6. DOI 10.1345/aph.17400
22. Xu QA, Trissel LA, Zhang Y, Martinez JF, Gilbert DL. Stability of thiotepa (lyophilized) in 5% dextrose injection at 4 and 23 degrees C. Am J Health Syst Pharm 1996;53:2728-30.
23. Craig SB, Bhatt UH, Patel K. Stability and compatibility of topotecan hydrochloride for injection with common infusion solutions and containers. J Pharm Biomed Anal 1997;16:199-205.
24. Kleinberg ML, Chang P. Overfill of common piggybag admixture solutions. Hosp Pharm 1984;19:657-8.
25. Galanti LM, Hecq JD, Vanbeckbergen D, Jamart J. Long-term stability of cefuroxime and cefazolin sodium intravenous infusions. J Clin Pharm Ther 1996;21:185-9.
26. Hecq JD, Berlage V, Vanbeckbergen D, Jamart J, Galanti L. Effects of freezing, long-term storage and microwave thawing on the stability of piperacillin plus tazobactam in 5% dextrose for infusion. Can J Hosp Pharm 2004;57: 276-82.
27. Lebrun J, Hecq JD, Vanbeckbergen D, Jamart J, Galanti L. Effect of freezing, long-term storage and microwave thawing on the stability of tramadol in 5% dextrose infusion P.V.C. bags. Int J Pharm Compound 2004;8:156-9.
28. Schlesser V, Hecq JD, Vanbeckbergen D, Jamart J, Galanti L. Effect of freezing, long-term storage and microwave thawing on the stability of cefepime in 5% dextrose infusion P.V.C. bags. Int J Pharm Compound 2002; 6:391-4.
29. Guideline for submitting documentation for the stability of human drugs and biologies. Rockville, MD: Food and Drug Administration, 1987. www.fda.gov/cder/guidance/cmc2.pdf (accessed 2004 Dec 2).
30. Ruberg SJ, Stegeman JW. Pooling data for stability studies: testing the equality of batch degradation slopes. Biometrics 1991;47:1059-69.
31. Galanti LM, Hecq JD, Vanbeckbergen D, Jamart J. Long-term stability of vancomycin hydrochloride in intravenous infusions. J Clin Pharm Ther 1997;22:353-6.
32. Galanti LM, Hecq JD, Jeuniau PH, Vanbeckbergen D, Jamart J. Assessment of the stability of teicoplanin in intravenous infusions. Int J Pharmaceut Compound 2001;5:397-400.
33. Boitquin L, Hecq JD, Evrard J-M, Vanbeckbergen D, Jamart J, Galanti L. Long-term stability of sufentanil citrate with levobupivacaine HCl in 0.9% sodium chloride infusion PVC bags at 4 °C. J Pain Symptom Manage 2004;28:4-6.
34. Boitquin LP, Hecq JD, Vanbeckbergen DF, Jamart J, Galanti LM. Stability of sufentanil citrate with levobupivacaine HCl in NaCl 0.9% infusion after microwave freeze-thaw treatment. Ann Pharmacother 2004;38: 1836-9. DOI 10.1345/aph.1D564