Randomized, double-blind study comparing postoperative effects of treatment timing with histamine H2-receptor antagonist cimetidine

Acta Anaesthesiologica Scandinavica

Volumn 49, Issue 6, 2005, Pages 865-869

  Chia, Y Y ^a,b   Chiang, H L ^a   Liu, K ^a   Ko, N H ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Analgesia: Postoperative; Histamine H2 receptor antagonist: cimetidine; Patient controlled analgesia; Pre emptive analgesia

Indexed keywords

CIMETIDINE; HISTAMINE H2 RECEPTOR ANTAGONIST; MORPHINE; PLACEBO; SODIUM CHLORIDE;

ABDOMINAL SURGERY; ADULT; ANESTHESIA INDUCTION; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG UTILIZATION; FEMALE; GENERAL ANESTHESIA; GYNECOLOGIC SURGERY; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; NAUSEA; OPIOID INDUCED EMESIS; PAIN ASSESSMENT; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RESPIRATION DEPRESSION; SEDATION; SIDE EFFECT;

ADULT; ANALGESICS, OPIOID; CIMETIDINE; DOUBLE-BLIND METHOD; FEMALE; GYNECOLOGIC SURGICAL PROCEDURES; HISTAMINE H2 ANTAGONISTS; HUMANS; INJECTIONS, INTRAVENOUS; MIDDLE AGED; MORPHINE; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; POSTOPERATIVE COMPLICATIONS; POSTOPERATIVE NAUSEA AND VOMITING;

EID: 21744451637     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2005.00696.x     Document Type: Article

References (21)

1. 2 blocking agents reduces the incidence of postoperative nausea and vomiting. Inflamm Res 2004; 53 (Suppl. 2): S154-8.
2. Sunshine A, Zighelboim I, De Castro A et al. Augmentation of acetaminophen analgesia by the antihistamine phenyltoloxamine. J Clin Pharmacol 1989; 29: 660-4.
3. Rumore MM, Schlichting DA. Analgesic effects of antihistaminics. Life Sci 1985; 36: 403-16.
4. Campos VM, Solis EL. The analgesic and hypothermic effects of nefopam, morphine, aspirin, diphenhydramine, and placebo. J Clin Pharmacol 1980; 20: 42-9.
5. Chia YY, Lo Y, Liu K et al. The effect of promethazine on postoperative pain: a comparison of preoperative, post-operative, and placebo administration in patients following total abdominal hysterectomy. Acta Anaesthesiol Scand 2004; 48: 625-30.
6. Lam AM, Grace DM, Penny FJ, Vezina WC. Prophylactic intravenous cimetidine reduces the risk of acid aspiration in morbidly obese patients. Anaesthesiology 1986; 65: 684-7.
7. 2-receptor agonists and antagonists on nociception in the rat. Agents Actions 1988; 23: 247-9.
8. Netti C, Bossa R, Galatulas I et al. Antinociceptive effect of centrally administered cimetidine and dimaprit in the rat. Pharmacology 1984; 28: 262-7.
9. Oluyomi AO, Hart SL. Involvement of histamine in naloxone-resistant and naloxone-sensitive models of swim stress-induced antinociception in the mouse. Neuropharmacology 1991; 30: 1021-7.
10. 2- histamine receptor blockers and opiate analgesia in mice. Meth Find Exp Clin Pharmacol 1990; 12: 671-8.
11. 2- antihistaminics in mice. Gen Pharmac 1993; 24: 1173-6.
12. Ashmawi HA, Chambergo FS, Palmeira CCA, Posso IP. The effect of pyrilamine and cimetidine on mRNA C-fos expression and nociceptive flinching behavior in rats. Anesth Analg 2003; 97: 541-6.
13. Yokoyama M, Aono H, Takeda A, Morita K. Cimetidine for chronic calcifying tendonitis of the shoulder. Reg Anesth Pain Med 2003; 28: 248-52.
14. Katz J. Pre-emptive analgesia: evidence, current status and future directions. Eur J Anaesthesiol Suppl 1995; 10: 8-13.
15. McCartney CJL, Sinha A, Katz J. A qualitative systemic review of the role of N-Methyl-D-Aspartate receptor antagonists in preventive analgesia. Anesth Analg 2004; 98: 1385-400.
16. 3 antagonists and derivatives. J Pharmacol Exp Ther 1997; 283: 1534-43.
17. Hough LB, Nalwalk JW, Chen Y et al. Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice. Brain Res 2000; 880: 102-8.
18. 1 receptor mediated excitation and facilitation of the heat response by histamine in canine visceral polymodal receptors studied in vitro. J Neurophysiol 1996; 76: 1396-404.
19. Jonsson KA, Eriksson SE, Kagevi I et al. No detectable concentrations of oxmetidine but measurable concentrations of cimetidine in cerebrospinal fluid (CSF) during multiple dose treatment. Br J Clin Pharmacol 1984; 17: 781-2.
20. Kimelblatt BJ, Cerra FB, Calleri G et al. Dose and serum concentration relationships in cimetidine-associated mental confusion. Gastroenterology 1980; 78: 791-5.
21. Miller AD. Central mechanisms of vomiting. Dig Dis Sci 1999; 44 (8 Suppl.): 39S-43S.