Treatment options for POEMS syndrome

Expert Opinion on Pharmacotherapy

Volumn 6, Issue 6, 2005, Pages 945-953

  Dispenzieri, Angela ^a   Gertz, Morie A ^a  

^a MAYO CLINIC   (United States)

Author keywords

Castleman's disease; Monoclonal gammopathy of undetermined significance; Multiple myeloma; Paraneoplastic syndrome; POEMS syndrome; Vascular endothelial growth factor

Indexed keywords

ALKYLATING AGENT; AZATHIOPRINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; DEXAMETHASONE; IMMUNOGLOBULIN; LEXIDRONAM SAMARIUM SM 153; MELPHALAN; PREDNISONE; STRONTIUM 89; THALIDOMIDE;

ACUTE LEUKEMIA; ANGIOFOLLICULAR LYMPH NODE HYPERPLASIA; ASCITES; BONE LESION; CHEMOTHERAPY; CLUBBING FINGERS; CORTICOSTEROID THERAPY; DISEASE EXACERBATION; ENDOCRINE DISEASE; FLUID RETENTION; HUMAN; LOW DRUG DOSE; MYELODYSPLASTIC SYNDROME; OSTEOSCLEROSIS; PAPILLEDEMA; PARANEOPLASTIC SYNDROME; PARAPROTEINEMIA; PATHOGENESIS; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; PERIPHERAL EDEMA; PERIPHERAL NEUROPATHY; PLASMA CELL DYSCRASIA; PLASMACYTOMA; PLASMAPHERESIS; PLEURA EFFUSION; RETROSPECTIVE STUDY; REVIEW; SKIN MANIFESTATION; SYSTEMIC THERAPY; THROMBOCYTOSIS;

ANTINEOPLASTIC AGENTS; HUMANS; PLASMAPHERESIS; POEMS SYNDROME; STEM CELL TRANSPLANTATION; SURVIVAL RATE;

EID: 21744438606     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.6.6.945     Document Type: Review

References (56)

1. BARDWICK PA, ZVAIFLER NJ, GILL GN et al.: Plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes: the POEMS syndrome. Report on two cases and a review of the literature. Medicine (1980) 59(4):311-322.
2. DISPENZIERT A, KYLE RA, LACY MQ et al.: POEMS syndrome: definitions and long-term outcome. Blood (2003) 101(7):2496-2506.
3. NAKANISHI T, SOBUE I, TOYOKURA Y et al.: The Crow-Fukase syndrome: a study of 102 cases in Japan. Neurology (1984) 34(6):712-720.
4. SOUBRIER M, DUBOST JJ, SERRE AF et al.: Growth factors in POEMS syndrome: evidence for a marked increase in circulating vascular endothelial growth factor. Arthritis Rheum. (1997) 40(4):786-787.
5. WATANABE O, MARUYAMA I, ARIMURA K et al.: Overproduction of vascular endothelial growth factor/vascular permeability factor is causative in Crow-Fukase (POEMS) syndrome. Muscle Nerve (1998) 21(11):1390-1397.
6. GHERARDI RK, BELEC L, SOUBRIER M et al.: Overproduction of proinflammatory cytokines imbalanced by their antagonists in POEMS syndrome. Blood (1996) 87(4):1458-1465.
7. BELEC L, MOHAMED AS, AUTHIER FJ et al.: Human herpesvirus 8 infection in patients with POEMS syndrome-associated multicentric Castlemans disease. Blood (1999) 93(11):3643-3653.
8. BERGOUIGNAN FX, MASSONNAT R, VITAL C et al.: Uncompacted lamellae in three patients with POEMS syndrome. Eur Neurol. (1987) 27(3):173-181.
9. DISPENZIERI A, MORENO-ASPITIA A, LACY MQ et al.: Peripheral blood stem cell transplant (PBSCT) in a large series of patients with POEMS syndrome. Biol. Blood Marrow Transplant. (2004) 10(2):14-15.
10. IWASAKI H, OGAWA K, YOSHIDA H et al.: Crow-Fukase syndrome associated with pulmonary hypertension. Intern. Med. (1993) 32(7):556-560.
11. LESPRIT P, GODEAU B, AUTHIER FJ et al.: Pulmonary hypertension in POEMS syndrome: a new feature mediated by cytokines. Am. J. Respir. Crit. Care Med. (1998) 157(3 Pt. 1):907-911.
12. KELLY JJ JR, KYLE RA, MILES JM et al.: Osteosclerotic myeloma and peripheral neuropathy. Neurology (1983) 33(2):202-210.
13. TAKATSUKI K, SANADA I: Plasma cell dyscrasia with polyneuropathy and endocrine disorder: clinical and laboratory features of 109 reported cases. Jpn. J. Clin. Oncol. (1983) 13(3):543-555.
14. SUAREZ GA, DISPENZIERI A, GERTZ MA et al.: The electrophysiologic findings of the peripheral neuropathy associated with POEMS. Clin Neurophysiol. (2002) 113(Suppl.1): S9.
15. SUNG JY, KUWABARA S, OGAWARA K et al.: Patterns of nerve conduction abnormalities in POEMS syndrome. Muscle Nerve (2002) 26(2):189-193.
16. OREFICE G, MORRA VB, DF MICHELE G et al.: POEMS syndrome: clinical, pathological and immunological study of a case. Neurol. Res. (1994) 16(6):477-480.
17. CRISCI C, BARBIERI F, PARENTE D et al.: POEMS syndrome: follow-up study of a case. Clin. Neurol. Neurosurg. (1992) 94(1):65-68.
18. VITAL C, VITAL A, FERRER X et al.: 'Crow - Fukase (POEMS) syndrome: a study of peripheral nerve biopsy in five new cases.' J. Peripher. Nerv. Syst. (2003) 8(3):136-144.
19. SOUBRIER MJ, DUBOST JJ, SAUVEZIE BJ: POEMS syndrome: a study of 25 cases and a review of the literature. French Study Group on POEMS Syndrome. Am. J. Med. (1994) 97(6):543-553.
20. DAVIS L, DRACHMAN D: Myeloma Neuropathy. Arch. Neurol. (1972) 27:507-511.
21. IWASHITA H, OHNISHI A, ASADA M et al.: Polyneuropathy, skin hyperpigmentation, edema, and hypertrichosis in localized osteosclerotic myeloma. Neurology (1977) 27(7):675-681.
22. MORLEY JB, SCHWIEGER AC: The relation between chronic polyneuropathy and osteosclerotic myeloma. J. Neurol. Neurosurg. Psych. (1967) 30(5):432-442.
23. ARIMA F, DOHMEN K, YAMANO Y et al.: Five cases of Crow-Fukase syndrome. Eukuoka Igaku Zasshi Fukuoka Acta Medica (1992) 83(2):112-120.
24. SANO M, TERASAKI T, KOYAMA A et al.: Glomerular lesions associated with the Crow - Fukase syndrome. Virchows Arch. A Pathol. Anat. Histopathol. (1986) 409(1):3-9.
25. HENZE T, KRIEGER G: Combined high-dose 7S-IgG and dexamethasone is effective in severe polyneuropathy of the POEMS syndrome. J. Neurol. (1995) 242(7):482-483.
26. ROTTA FT, BRADLEY WG: Marked improvement of severe polyneuropathy associated with multifocal osteosclerotic myeloma following surgery, radiation, and chemotherapy. Muscle Nerve (1997) 20(8):1035-1037.
27. ATSUMI T, KATO K, KUROSAWA S et al.: A case of Crow - Fukase syndrome with elevated soluble interleukin-6 receptor in cerebrospinal fluid. Response to double-filtration plasmapheresis and corticosteroids. Acta Haematol. (1995) 94(2):90-94.
28. KUWABARA S, HATTORI T, SHIMOE Y et al.: Long term melphalan-prednisolone chemotherapy for POEMS syndrome. J. Neurol Neurosurg. Psychiatr. (1997) 63(3):385-387.
29. STEWART PM, MCINTYRE MA, EDWARDS CR: The endocrinopathy of POEMS syndrome. Scott. Med. J. (1989) 34(5):520-522.
30. REULECKE M, DUMAS M & MEIER C: Specific antibody activity against neuroendocrine tissue in a case of POEMS syndrome with IgG gammopathy. Neurology (1988) 38(4):614-616.
31. CABEZAS-AGRICOLA JM, LADO-ABEAL JJ, OTERO-ANTON E et al.: Hypoparathyroidism in POEMS syndrome. Lancet (1996) 347(9002):701-702
32. KU A, LACHMANN E, TUNKEL R et al. Severe polyneuropathy: initial manifestation of Castleman's disease associated with POEMS syndrome. Arch. Phys. Med. Rehab. (1995) 76(7):692-694.
33. REITAN JB, PAPE E, FOSSA SD et al.: Osteosclerotic myeloma with polyneuropathy. Acta Medica Scandinavica (1980) 208(1-2):137-144.
34. [NO AUTHORS LISTED] Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials. Myeloma Trialists' Collaborative Group. J. Clin. Oncol. (1998) 16(12):3832-3842.
35. SATOH K, MIURA I, CHUBACHI A et al.: Development of secondary leukemia associated with (1;7)(q10;p10) in a patient with Crow - Fukase syndrome. Intern. Med. (1996) 35(8):660-662.
36. WONG VA, WADE NK: POEMS syndrome: an unusual cause of bilateral optic disk swelling. Am. J. Ophthalmol. (1998) 126(3):452-454.
37. HOGAN WJ, LACY MQ, WISEMAN GA et al.: Successful treatment of POEMS syndrome with autologous hematopoietic progenitor cell transplantation. Bone Marrow Transplant (2001) 28(3):305-309.
38. JACCARD A, ROYER B, BORDESSOULE D et al.: High-dose therapy and autologous blood stem cell transplantation in POEMS syndrome. Blood (2002) 99(8):3057-3059.
39. PEGGS KS, PANEESHA S, KOTTARIDIS PD et al.: Peripheral blood stem cell transplantation for POEMS syndrome. Bone Marrow Transplant (2002) 30(6):401-404.
40. ROVIRA M, CARRERAS E, BLADE J et al.: Dramatic improvement of POEMS syndrome following autologous haematopoietic cell transplantation. Br. J. Haematol. (2001) 115(2):373-375.
41. SOUBRIER M, RUIVARD M, DUBOST JJ et al.: Successful use of autologous bone marrow transplantation in treating a patient with POEMS syndrome. Bone Marrow Transplant (2002) 30(1):61-62.
42. DISPENZIERI A, MORENO-ASPITIA A, SUAREZ CA et al.: Peripheral blood stem cell transplantation in 16 patients with POEMS syndrome, and a review of the literature. Blood (2004) 104(10):3400-3407.
43. ATTAL M, HAROUSSEAU JL, STOPPA AM et al.: A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple in myeloma. Intergroupe Francais du Myelome. N. Engl. J. Med. (1996) 335(2):91-97.
44. GERTZ MA, LACY MQ DISPENZIERI A et al.: Stem cell transplantation for the management of primary systemic amyloidosis. Am. J. Med. (2002) 113(7):549-555.
45. SINISALO M, HIETAHARJU A, SAURANEN J et al.: Thalidomide in POEMS syndrome: case report. Am. J. Hematol. (2004) 76(1):66-68.
46. SINGHAL S, MEHTA J, DESIKAN R et al.: Antitumor activity of thalidomide in refractory multiple myeloma. N. Engl. J. Med. (1999) 341(21):1565-1571.
47. DISPENZIERI A, LACY MQ, RAJKUMAR SV et al.: Poor tolerance to high doses of thalidomide in patients with primary systemic amyloidosis. Amyloid (2003) 10(4):257-261.
48. AUTHIER FJ, BELEC L, LEVY Y et al.: All-trans-retinoic acid in POEMS syndrome. Therapeutic effect associated with decreased circulating levels of proinflammatory cytokines. Arth. Rheum. (1996) 39(8):1423-1426.
49. BENITO-LEON J, LOPEZ-RIOS F, RODRIGUEZ-MARTIN FJ et al.: Rapidly deteriorating polyneuropathy associated with osteosclerotic myeloma responsive to intravenous immunoglobulin and radiotherapy. J. Neurol. Sci. (1998) 158(1):113-117.
50. COTO V, AULETTA M, OLIVIERO U et al.: POEMS syndrome: an Italian case with diagnostic and therapeutic implications. Ann. Ital. Med. Int. (1991) 6(4):416-419.
51. FRASSICA DA, FRASSICA FJ, SCHRAY MF et al.: Solitary plasmacytoma of bone: Mayo Clinic experience. Int. J. Radiat. Oncol. Biol. Phys. (1989) 16(1):43-48.
52. MENDENHALL CM, THAR TL & MILLION RR: Solitary plasmacytoma of bone and soft tissue. Int. J. Radiat. Oncol. Biol Phys. (1980) 6(11):1497-1501.
53. STERNBERG AJ, DAVIES P, MACMILLAN C et al.: Strontium-89: a novel treatment for a case of osteosclerotic myeloma associated with life-threatening neuropathy. Br. J. Haematol. (2002) 118(3):821-824.
54. BROUSSOLLE E, VIGHETTO A, BANCEL B et al.: POEMS syndrome with complete recovery after treatment of a solitary plasmocytoma. Clin. Neurol. Neurosurg. (1991) 93(2):165-170.
55. FURUZONO H, MORITOYO T, YAMADA H et al.: A case of Crow - Fukase syndrome which developed seven years following myelopathy of unknown origin. Rinsho Shinkeigaku Clin. Neurol. (1993) 33(1)):56-60.
56. SILBERSTEIN LE, DUGGAN D & BERKMAN EM: Therapeutic trial of plasma exchange in osteosclerotic myeloma associated with the POEMS syndrome. J. Clin. Apheresis (1985) 2(3):253-257.