메뉴 건너뛰기




Volumn 6, Issue SUPPL. 1, 2005, Pages

Role of fulvestrant in sequential hormonal therapy for advanced, hormone receptor- Positive breast cancer in postmenopausal women

Author keywords

Antiestrogen; Second line treatment; Sequencing; Third line treatment

Indexed keywords

ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; AROMATASE INHIBITOR; DRUG DERIVATIVE; ESTRADIOL; ESTROGEN RECEPTOR; FULVESTRANT;

EID: 21744434395     PISSN: 15268209     EISSN: None     Source Type: Journal    
DOI: 10.3816/CBC.2005.s.010     Document Type: Article
Times cited : (4)

References (66)
  • 1
    • 0034984594 scopus 로고    scopus 로고
    • Endocrine therapy in the treatment of metastatic breast cancer
    • Buzdar AU. Endocrine therapy in the treatment of metastatic breast cancer. Semin Oncol 2001; 28:291-304.
    • (2001) Semin Oncol , vol.28 , pp. 291-304
    • Buzdar, A.U.1
  • 2
    • 0036319584 scopus 로고    scopus 로고
    • To block estrogen's synthesis or action: That is the question
    • Santen RJ. To block estrogen's synthesis or action: that is the question. J Clin Endocrinol Metab 2002; 87:3007-3012.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3007-3012
    • Santen, R.J.1
  • 3
    • 1642568637 scopus 로고    scopus 로고
    • Sequencing of endocrine therapy in postmenopausal women with advanced breast cancer
    • Ingle JN. Sequencing of endocrine therapy in postmenopausal women with advanced breast cancer. Clin Cancer Res 2004; 10(suppl):362s-367s.
    • (2004) Clin Cancer Res , vol.10 , Issue.SUPPL.
    • Ingle, J.N.1
  • 4
    • 0019382847 scopus 로고
    • Randomized clinical trial of diethylstilbestrol versus tamoxifen in postmenopausal women with advanced breast cancer
    • Ingle JN, Ahmann DL, Green SJ, et al. Randomized clinical trial of diethylstilbestrol versus tamoxifen in postmenopausal women with advanced breast cancer. N Engl J Med 1981; 304:16-21.
    • (1981) N Engl J Med , vol.304 , pp. 16-21
    • Ingle, J.N.1    Ahmann, D.L.2    Green, S.J.3
  • 5
    • 0033058968 scopus 로고    scopus 로고
    • Randomized trial of diethylstilbestrol vs. tamoxifen in postmenopausal women with metastatic breast cancer: An updated analysis
    • Peethambaram P P, Ingle JN, Suman VJ, et al. Randomized trial of diethylstilbestrol vs. tamoxifen in postmenopausal women with metastatic breast cancer: an updated analysis. Breast Cancer Res Treat 1999; 54:117-122.
    • (1999) Breast Cancer Res Treat , vol.54 , pp. 117-122
    • Peethambaram, P.P.1    Ingle, J.N.2    Suman, V.J.3
  • 6
    • 0036041129 scopus 로고    scopus 로고
    • Estrogen as therapy for breast cancer
    • Ingle JN. Estrogen as therapy for breast cancer. Breast Cancer Res 2002; 4:133-136.
    • (2002) Breast Cancer Res , vol.4 , pp. 133-136
    • Ingle, J.N.1
  • 7
    • 0022901001 scopus 로고
    • Megestrol acetate v tamoxifen in advanced breast cancer: Correlation of hormone receptors and response
    • Ettinger DS, Allegra J, Bertino JR, et al. Megestrol acetate v tamoxifen in advanced breast cancer: correlation of hormone receptors and response. Semin Oncol 1986; 13(suppl 4):9-14.
    • (1986) Semin Oncol , vol.13 , Issue.SUPPL. 4 , pp. 9-14
    • Ettinger, D.S.1    Allegra, J.2    Bertino, J.R.3
  • 8
    • 0027433430 scopus 로고
    • Randomized comparison of the effects of tamoxifen, megestrol acetate, or tamoxifen plus megestrol acetate on treatment response and survival in patients with metastatic breast cancer
    • Gill PG, Gebski V, Snyder R, et al. Randomized comparison of the effects of tamoxifen, megestrol acetate, or tamoxifen plus megestrol acetate on treatment response and survival in patients with metastatic breast cancer. Ann Oncol 1993; 4:741-744.
    • (1993) Ann Oncol , vol.4 , pp. 741-744
    • Gill, P.G.1    Gebski, V.2    Snyder, R.3
  • 9
    • 0020472669 scopus 로고
    • Randomized clinical trial of megestrol acetate versus tamoxifen in paramenopausal or castrated women with advanced breast cancer
    • Ingle JN, Ahmann DL, Green SJ, et al. Randomized clinical trial of megestrol acetate versus tamoxifen in paramenopausal or castrated women with advanced breast cancer. Am J Clin Oncol 1982; 5:155-160.
    • (1982) Am J Clin Oncol , vol.5 , pp. 155-160
    • Ingle, J.N.1    Ahmann, D.L.2    Green, S.J.3
  • 10
    • 0024041157 scopus 로고
    • Megestrol acetate versus ta-moxifen in advanced breast cancer: 5-year analysis: a phase III trial of the Piedmont Oncology Association
    • Muss HB, Wells HB, Paschold EH, et al. Megestrol acetate versus ta-moxifen in advanced breast cancer: 5-year analysis: a phase III trial of the Piedmont Oncology Association. J Clin Oncol 1988; 6:1098-1106.
    • (1988) J Clin Oncol , vol.6 , pp. 1098-1106
    • Muss, H.B.1    Wells, H.B.2    Paschold, E.H.3
  • 11
    • 0025686166 scopus 로고
    • Comparison of antiestrogen and progestogen therapy for initial treatment and consequences of their combination for second-line treatment of recurrent breast cancer
    • Paterson AH, Hanson J, Pritchard KI, et al. Comparison of antiestrogen and progestogen therapy for initial treatment and consequences of their combination for second-line treatment of recurrent breast cancer. Semin Oncol 1990; 17(suppl 9):52-62.
    • (1990) Semin Oncol , vol.17 , Issue.SUPPL. 9 , pp. 52-62
    • Paterson, A.H.1    Hanson, J.2    Pritchard, K.I.3
  • 12
    • 0030272671 scopus 로고    scopus 로고
    • A randomised phase III cross-over study of tamoxifen versus megestrol acetate in advanced and recurrent breast cancer
    • Stuart NS, Warwick J, Blackledge GR, et al. A randomised phase III cross-over study of tamoxifen versus megestrol acetate in advanced and recurrent breast cancer. Eur J Cancer 1996; 32A:1888-1892.
    • (1996) Eur J Cancer , vol.32 A , pp. 1888-1892
    • Stuart, N.S.1    Warwick, J.2    Blackledge, G.R.3
  • 13
    • 0032530988 scopus 로고    scopus 로고
    • Anastrozole versus megestrol acetate in the treatment of postmenopausal women with advanced breast carcinoma: Results of a survival update based on a combined analysis of data from two mature phase III trials
    • Buzdar AU, Jonat W, Howell A, et al. Anastrozole versus megestrol acetate in the treatment of postmenopausal women with advanced breast carcinoma: results of a survival update based on a combined analysis of data from two mature phase III trials. Cancer 1998; 83:1142-1152.
    • (1998) Cancer , vol.83 , pp. 1142-1152
    • Buzdar, A.U.1    Jonat, W.2    Howell, A.3
  • 14
    • 0035879215 scopus 로고    scopus 로고
    • Phase III, multicenter, double-blind, randomized study of letrozole, an aromatase inhibitor, for advanced breast cancer versus megestrol acetate
    • Buzdar A, Douma J, Davidson N, et al. Phase III, multicenter, double-blind, randomized study of letrozole, an aromatase inhibitor, for advanced breast cancer versus megestrol acetate. J Clin Oncol 2001; 19:3357-3366.
    • (2001) J Clin Oncol , vol.19 , pp. 3357-3366
    • Buzdar, A.1    Douma, J.2    Davidson, N.3
  • 15
    • 0031943424 scopus 로고    scopus 로고
    • Letrozole, a new oral aromatase inhibitor for advanced breast cancer: Double-blind randomized trial showing a dose effect and improved efficacy and tolerability compared with megestrol acetate
    • Dombernowsky P, Smith I, Falkson G, et al. Letrozole, a new oral aromatase inhibitor for advanced breast cancer: double-blind randomized trial showing a dose effect and improved efficacy and tolerability compared with megestrol acetate. J Clin Oncol 1998; 16:453-461.
    • (1998) J Clin Oncol , vol.16 , pp. 453-461
    • Dombernowsky, P.1    Smith, I.2    Falkson, G.3
  • 16
    • 0033736549 scopus 로고    scopus 로고
    • Exemestane improves survival compared with megoestrol acetate in postmenopausal patients with advanced breast cancer who have failed on tamoxifen: Results of a double-blind randomised phase III trial
    • Kaufmann M, Bajetta E, Dirix LY, et al. Exemestane improves survival compared with megoestrol acetate in postmenopausal patients with advanced breast cancer who have failed on tamoxifen: results of a double-blind randomised phase III trial. Eur J Cancer 2000; 36(suppl):S86-S87.
    • (2000) Eur J Cancer , vol.36 , Issue.SUPPL.
    • Kaufmann, M.1    Bajetta, E.2    Dirix, L.Y.3
  • 17
    • 0034669435 scopus 로고    scopus 로고
    • Anastrozole versus tamoxifen as first-line therapy for advanced breast cancer in 668 postmenopausal women: Results of the Tamoxifen or Arimidex Randomized Group Efficacy and Tolerability study
    • Bonneterre J, Thürlimann B, Robertson JFR, et al. Anastrozole versus tamoxifen as first-line therapy for advanced breast cancer in 668 postmenopausal women: results of the Tamoxifen or Arimidex Randomized Group Efficacy and Tolerability study. J Clin Oncol 2000; 18:3748-3757.
    • (2000) J Clin Oncol , vol.18 , pp. 3748-3757
    • Bonneterre, J.1    Thürlimann, B.2    Robertson, J.F.R.3
  • 18
    • 0037841365 scopus 로고    scopus 로고
    • Anastrozole versus tamoxifen as first-line therapy in postmenopausal patients with hormonedependent advanced breast cancer: A prospective, randomized, phase III study
    • Milla-Santos A, Milla L, Portella J, et al. Anastrozole versus tamoxifen as first-line therapy in postmenopausal patients with hormonedependent advanced breast cancer: a prospective, randomized, phase III study. Am J Clin Oncol 2003; 26:317-322.
    • (2003) Am J Clin Oncol , vol.26 , pp. 317-322
    • Milla-Santos, A.1    Milla, L.2    Portella, J.3
  • 19
    • 0038460245 scopus 로고    scopus 로고
    • Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: Analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group
    • Mouridsen H, Gershanovich M, Sun Y, et al. Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group. J Clin Oncol 2003; 21:2101-2109.
    • (2003) J Clin Oncol , vol.21 , pp. 2101-2109
    • Mouridsen, H.1    Gershanovich, M.2    Sun, Y.3
  • 20
    • 0034669484 scopus 로고    scopus 로고
    • Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in post-menopausal women: Results of a North American multicenter randomized trial
    • Nabholtz JM, Buzdar A, Pollak M, et al. Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in post-menopausal women: results of a North American multicenter randomized trial. J Clin Oncol 2000; 18:3758-3767.
    • (2000) J Clin Oncol , vol.18 , pp. 3758-3767
    • Nabholtz, J.M.1    Buzdar, A.2    Pollak, M.3
  • 21
    • 0042848744 scopus 로고    scopus 로고
    • Anastrozole (Arim-idex) versus tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: Survival analysis and updated safety results
    • Nabholtz JM, Bonneterre J, Buzdar A, et al. Anastrozole (Arim-idex") versus tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: survival analysis and updated safety results. Eur J Cancer 2003; 39:1684-1689.
    • (2003) Eur J Cancer , vol.39 , pp. 1684-1689
    • Nabholtz, J.M.1    Bonneterre, J.2    Buzdar, A.3
  • 22
    • 0141836855 scopus 로고    scopus 로고
    • Mature results of a randomized phase II multicenter study of exemestane versus tamoxifen as first-line hormone therapy for postmenopausal women with metasta-tic breast cancer
    • Paridaens R, Dirix L, Lohrisch C, et al. Mature results of a randomized phase II multicenter study of exemestane versus tamoxifen as first-line hormone therapy for postmenopausal women with metasta-tic breast cancer. Ann Oncol 2003; 14:1391-1398.
    • (2003) Ann Oncol , vol.14 , pp. 1391-1398
    • Paridaens, R.1    Dirix, L.2    Lohrisch, C.3
  • 23
    • 84898694927 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network. Breast Cancer. Clinical Practice Guidelines in Oncology - v.1.2005. Available at: http://www.nccn.org/ professionals/physician-gls/default.asp. Accessed March 30, 2005.
    • National Comprehensive Cancer Network. Breast Cancer. Clinical Practice Guidelines in Oncology - v.1.2005. Available at: http://www.nccn.org/ professionals/physician-gls/default.asp. Accessed March 30, 2005.
  • 24
    • 0037157603 scopus 로고    scopus 로고
    • Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial
    • Baum M, Buzdar AU, Cuzick J, et al. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. Lancet 2002; 359:2131-2139.
    • (2002) Lancet , vol.359 , pp. 2131-2139
    • Baum, M.1    Buzdar, A.U.2    Cuzick, J.3
  • 25
    • 0142181118 scopus 로고    scopus 로고
    • Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: Results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses
    • Baum M, Buzdar A, Cuzick J, et al. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses. Cancer 2003; 98:1802-1810.
    • (2003) Cancer , vol.98 , pp. 1802-1810
    • Baum, M.1    Buzdar, A.2    Cuzick, J.3
  • 26
    • 1542294319 scopus 로고    scopus 로고
    • Anastrozole appears to be superior to tamoxifen in women already receiving adjuvant tamox-ifen treatment
    • Abstract, 3
    • Boccardo F, Rubagotti A, Amoroso D, et al. Anastrozole appears to be superior to tamoxifen in women already receiving adjuvant tamox-ifen treatment Breast Cancer Res Treat 2003; 82(suppl 1):S6 (Abstract #3).
    • (2003) Breast Cancer Res Treat , vol.82 , Issue.SUPPL. 1
    • Boccardo, F.1    Rubagotti, A.2    Amoroso, D.3
  • 27
    • 10744223655 scopus 로고    scopus 로고
    • A randomized trial of exemes-tane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer
    • Coombes RC, Hall E, Gibson LJ, et al. A randomized trial of exemes-tane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N Engl J Med 2004; 350:1081-1092.
    • (2004) N Engl J Med , vol.350 , pp. 1081-1092
    • Coombes, R.C.1    Hall, E.2    Gibson, L.J.3
  • 28
    • 21044435630 scopus 로고    scopus 로고
    • The Intergroup Exemestane Study: A randomized trial in postmenopausal patients with early breast cancer who remain disease-free after two to three years of ta-moxifen - updated survival analysis
    • Abstract, 3
    • Coombes RC, Hall E, Snowdon C F, et al. The Intergroup Exemestane Study: a randomized trial in postmenopausal patients with early breast cancer who remain disease-free after two to three years of ta-moxifen - updated survival analysis. Breast Cancer Res Treat 2004; 88(suppl 1):S7 (Abstract #3).
    • (2004) Breast Cancer Res Treat , vol.88 , Issue.SUPPL. 1
    • Coombes, R.C.1    Hall, E.2    Snowdon, C.F.3
  • 29
    • 7444259675 scopus 로고    scopus 로고
    • A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer
    • Goss PE, Ingle JN, Martino S, et al. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N Engl J Med 2003; 349:1793-1802.
    • (2003) N Engl J Med , vol.349 , pp. 1793-1802
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3
  • 30
    • 5444234822 scopus 로고    scopus 로고
    • Updated analysis of the NCIC CTG MA.17 randomized placebo (P) controlled trial of letrozole (L) after five years of tamoxifen in postmenopausal women with early stage breast cancer
    • Abstract
    • Goss PE, Ingle JN, Martino S, et al. Updated analysis of the NCIC CTG MA.17 randomized placebo (P) controlled trial of letrozole (L) after five years of tamoxifen in postmenopausal women with early stage breast cancer. Proc Am Soc Clin Oncol 2004; 23:87 (Abstract #847).
    • (2004) Proc Am Soc Clin Oncol , vol.23 , Issue.847 , pp. 87
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3
  • 31
    • 11444251764 scopus 로고    scopus 로고
    • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer
    • Howell A, Cuzick J, Baum M, et al. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet 2005; 365:60-62.
    • (2005) Lancet , vol.365 , pp. 60-62
    • Howell, A.1    Cuzick, J.2    Baum, M.3
  • 32
    • 14544273687 scopus 로고    scopus 로고
    • Benefits of switching post-menopausal women with hormone-sensitive early breast cancer to anastrozole after 2 years adjuvant tamoxifen: Combined results from 3,123 women enrolled in the ABCSG Trial 8 and the ARNO 95 Trial
    • Abstract, 2
    • Jakesz R, Kaufmann M, Gnant M, et al. Benefits of switching post-menopausal women with hormone-sensitive early breast cancer to anastrozole after 2 years adjuvant tamoxifen: combined results from 3,123 women enrolled in the ABCSG Trial 8 and the ARNO 95 Trial. Breast Cancer Res Treat 2004; 88(suppl 1):S7 (Abstract #2).
    • (2004) Breast Cancer Res Treat , vol.88 , Issue.SUPPL. 1
    • Jakesz, R.1    Kaufmann, M.2    Gnant, M.3
  • 33
    • 84898696799 scopus 로고    scopus 로고
    • Letrozole versus tamoxifen as adjuvant endocrine therapy for postmenopausal women with receptor-positive breast cancer. BIG 1-98: A prospective randomized double-blind phase III study
    • Presented at:, Switzerland. Abstract S4
    • Thürlimann B. Letrozole versus tamoxifen as adjuvant endocrine therapy for postmenopausal women with receptor-positive breast cancer. BIG 1-98: a prospective randomized double-blind phase III study. Presented at: The 9th International Congress on Primary Therapy of Early Breast Cancer; January 26-29, 2005; St. Gallen, Switzerland. Abstract S4.
    • The 9th International Congress on Primary Therapy of Early Breast Cancer; January 26-29, 2005; St. Gallen
    • Thürlimann, B.1
  • 34
    • 0025242415 scopus 로고
    • Endocrine pharmacology of antiestrogens as antitumor agents
    • Jordan VC, Murphy CS. Endocrine pharmacology of antiestrogens as antitumor agents. Endocr Rev 1990; 11:578-610.
    • (1990) Endocr Rev , vol.11 , pp. 578-610
    • Jordan, V.C.1    Murphy, C.S.2
  • 35
    • 0036232065 scopus 로고    scopus 로고
    • The evolution of tamoxifen therapy in breast cancer: Selective oestrogen-receptor modulators and downreg-ulators
    • O'Regan RM, Jordan VC. The evolution of tamoxifen therapy in breast cancer: selective oestrogen-receptor modulators and downreg-ulators. Lancet Oncol 2002; 3:207-214.
    • (2002) Lancet Oncol , vol.3 , pp. 207-214
    • O'Regan, R.M.1    Jordan, V.C.2
  • 36
    • 0023760993 scopus 로고
    • Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestro-gen administration
    • Gottardis MM, Jordan VC. Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestro-gen administration. Cancer Res 1988; 48:5183-5187.
    • (1988) Cancer Res , vol.48 , pp. 5183-5187
    • Gottardis, M.M.1    Jordan, V.C.2
  • 37
    • 0026768801 scopus 로고
    • Response after withdrawal of tamoxifen and progestogens in advanced breast cancer
    • Howell A, Dodwell DJ, Anderson H, et al. Response after withdrawal of tamoxifen and progestogens in advanced breast cancer. Ann Oncol 1992; 3:611-617.
    • (1992) Ann Oncol , vol.3 , pp. 611-617
    • Howell, A.1    Dodwell, D.J.2    Anderson, H.3
  • 38
    • 10744232401 scopus 로고    scopus 로고
    • Fulvestrant in postmenopausal women with advanced breast cancer
    • Bross P F, Baird A, Chen G, et al. Fulvestrant in postmenopausal women with advanced breast cancer. Clin Cancer Res 2003; 9:4309-4317.
    • (2003) Clin Cancer Res , vol.9 , pp. 4309-4317
    • Bross, P.F.1    Baird, A.2    Chen, G.3
  • 39
    • 0036279159 scopus 로고    scopus 로고
    • Fulvestrant: A review of its development, pre-clinical and clinical data
    • Wardley AM. Fulvestrant: a review of its development, pre-clinical and clinical data. Int J Clin Pract 2002; 56:305-309.
    • (2002) Int J Clin Pract , vol.56 , pp. 305-309
    • Wardley, A.M.1
  • 40
    • 0027768899 scopus 로고
    • The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling
    • Dauvois S, White R, Parker MG. The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling. J Cell Sci 1993; 106:1377-1388.
    • (1993) J Cell Sci , vol.106 , pp. 1377-1388
    • Dauvois, S.1    White, R.2    Parker, M.G.3
  • 41
    • 0027179615 scopus 로고
    • Action of "pure" antiestrogens in inhibiting estrogen receptor action
    • Parker MG. Action of "pure" antiestrogens in inhibiting estrogen receptor action. Breast Cancer Res Treat 1993; 26:131-137.
    • (1993) Breast Cancer Res Treat , vol.26 , pp. 131-137
    • Parker, M.G.1
  • 42
    • 0029883292 scopus 로고    scopus 로고
    • Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines
    • Pink JJ, Jordan VC. Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines. Cancer Res 1996; 56:2321-2330.
    • (1996) Cancer Res , vol.56 , pp. 2321-2330
    • Pink, J.J.1    Jordan, V.C.2
  • 43
    • 0030667676 scopus 로고    scopus 로고
    • Molecular basis of agonism and antagonism in the oestrogen receptor
    • Brzozowski AM, Pike AC, Dauter Z, et al. Molecular basis of agonism and antagonism in the oestrogen receptor. Nature 1997; 389:753-758.
    • (1997) Nature , vol.389 , pp. 753-758
    • Brzozowski, A.M.1    Pike, A.C.2    Dauter, Z.3
  • 44
    • 0029740105 scopus 로고    scopus 로고
    • Nuclear receptor coactivators and corepressors
    • Horwitz KB, Jackson TA, Bain DL, et al. Nuclear receptor coactivators and corepressors. Mol Endocrinol 1996; 10:1167-1177.
    • (1996) Mol Endocrinol , vol.10 , pp. 1167-1177
    • Horwitz, K.B.1    Jackson, T.A.2    Bain, D.L.3
  • 45
    • 0035884408 scopus 로고    scopus 로고
    • Robertson J F, Nicholson RI, Bundred NJ, et al. Comparison of the short-term biological effects of 7alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl) -nonyl]estra-1,3,5, (10)-triene-3,17beta-diol (Faslodex) versus tamoxifen in postmenopausal patients with primary breast cancer. Cancer Res 2001; 61:6739-6746.
    • Robertson J F, Nicholson RI, Bundred NJ, et al. Comparison of the short-term biological effects of 7alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl) -nonyl]estra-1,3,5, (10)-triene-3,17beta-diol (Faslodex) versus tamoxifen in postmenopausal patients with primary breast cancer. Cancer Res 2001; 61:6739-6746.
  • 46
    • 0026395885 scopus 로고
    • A potent specific pure antiestrogen with clinical potential
    • Wakeling AE, Dukes M, Bowler J. A potent specific pure antiestrogen with clinical potential. Cancer Res 1991; 5:3867-3873.
    • (1991) Cancer Res , vol.5 , pp. 3867-3873
    • Wakeling, A.E.1    Dukes, M.2    Bowler, J.3
  • 47
    • 0034023827 scopus 로고    scopus 로고
    • Similarities and distinctions in the mode of action of different classes of antioestrogens
    • Wakeling AE. Similarities and distinctions in the mode of action of different classes of antioestrogens. Endocr Relat Cancer 2000; 7:17-28.
    • (2000) Endocr Relat Cancer , vol.7 , pp. 17-28
    • Wakeling, A.E.1
  • 48
    • 0028246412 scopus 로고
    • The importance of tamoxifen metabolism in tamoxifen-stimulated breast tumor growth
    • Osborne CK, Jarman M, McCague R, et al. The importance of tamoxifen metabolism in tamoxifen-stimulated breast tumor growth. Cancer Chemother Pharmacol 1994; 34:89-95.
    • (1994) Cancer Chemother Pharmacol , vol.34 , pp. 89-95
    • Osborne, C.K.1    Jarman, M.2    McCague, R.3
  • 49
    • 0029075872 scopus 로고
    • Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer
    • Osborne CK, Coronado-Heinsohn EB, Hilsenbeck SG, et al. Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer. J Natl Cancer Inst 1995; 87:746-750.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 746-750
    • Osborne, C.K.1    Coronado-Heinsohn, E.B.2    Hilsenbeck, S.G.3
  • 50
    • 0037102121 scopus 로고    scopus 로고
    • Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment
    • Howell A, Robertson JFR, Quaresma Albano J, et al. Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment. J Clin Oncol 2002; 20:3396-3403.
    • (2002) J Clin Oncol , vol.20 , pp. 3396-3403
    • Howell, A.1    Robertson, J.F.R.2    Quaresma Albano, J.3
  • 51
    • 0037102126 scopus 로고    scopus 로고
    • Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: Results of a North American trial
    • Osborne CK, Pippen J, Jones SE, et al. Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial. J Clin Oncol 2002; 20:3386-3395.
    • (2002) J Clin Oncol , vol.20 , pp. 3386-3395
    • Osborne, C.K.1    Pippen, J.2    Jones, S.E.3
  • 52
    • 0038683988 scopus 로고    scopus 로고
    • Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma in post-menopausal women: A prospective combined analysis of two multi-center trials
    • Robertson JFR, Osborne CK, Howell A, et al. Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma in post-menopausal women: a prospective combined analysis of two multi-center trials. Cancer 2003; 98:229-238.
    • (2003) Cancer , vol.98 , pp. 229-238
    • Robertson, J.F.R.1    Osborne, C.K.2    Howell, A.3
  • 53
    • 0028861402 scopus 로고
    • Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer
    • Howell A, DeFriend D, Robertson J, et al. Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer. Lancet 1995; 345:29-30.
    • (1995) Lancet , vol.345 , pp. 29-30
    • Howell, A.1    DeFriend, D.2    Robertson, J.3
  • 54
    • 0030016280 scopus 로고    scopus 로고
    • Pharmacokinetics, pharmacological and anti-tumour effects of the specific anti-oestrogen ICI 182780 in women with advanced breast cancer
    • Howell A, DeFriend DJ, Robertson JFR, et al. Pharmacokinetics, pharmacological and anti-tumour effects of the specific anti-oestrogen ICI 182780 in women with advanced breast cancer. Br J Cancer 1996; 74:300-308.
    • (1996) Br J Cancer , vol.74 , pp. 300-308
    • Howell, A.1    DeFriend, D.J.2    Robertson, J.F.R.3
  • 55
    • 0041325578 scopus 로고    scopus 로고
    • Fulvestrant ('Faslodex') as hormonal treatment in postmenopausal patients with advanced breast cancer progressing after treatment with tamoxifen and aro-matase inhibitors
    • Abstract, 249
    • Perey L, Thurlimann B, Hawle H, et al. Fulvestrant ('Faslodex') as hormonal treatment in postmenopausal patients with advanced breast cancer progressing after treatment with tamoxifen and aro-matase inhibitors. Breast Cancer Res Treat 2002; 76(suppl 1):S72 (Abstract #249).
    • (2002) Breast Cancer Res Treat , vol.76 , Issue.SUPPL. 1
    • Perey, L.1    Thurlimann, B.2    Hawle, H.3
  • 56
    • 84898702471 scopus 로고    scopus 로고
    • Steger GC, Bartsch R, Wenzel C, et al. Fulvestrant beyond the second hormonal treatment line in metastatic breast cancer. Proc Am Soc Clin Oncol 2003; 22:20 (Abstract #78).
    • Steger GC, Bartsch R, Wenzel C, et al. Fulvestrant beyond the second hormonal treatment line in metastatic breast cancer. Proc Am Soc Clin Oncol 2003; 22:20 (Abstract #78).
  • 57
    • 2442648038 scopus 로고    scopus 로고
    • Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in post-menopausal women previously untreated with endocrine therapy: A multinational, double-blind, randomized trial
    • Howell A, Robertson J F, Abram P, et al. Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in post-menopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial. J Clin Oncol 2004; 22:1605-1613.
    • (2004) J Clin Oncol , vol.22 , pp. 1605-1613
    • Howell, A.1    Robertson, J.F.2    Abram, P.3
  • 59
    • 1842818696 scopus 로고    scopus 로고
    • Sensitivity to endocrine therapy is maintained in both fulvestrant- and tamoxifen-treated postmenopausal women with advanced breast cancer
    • Abstract, 173P
    • Howell A, Robertson JR. Sensitivity to endocrine therapy is maintained in both fulvestrant- and tamoxifen-treated postmenopausal women with advanced breast cancer. Ann Oncol 2002; 13(suppl 5):48 (Abstract #173P).
    • (2002) Ann Oncol , vol.13 , Issue.SUPPL. 5 , pp. 48
    • Howell, A.1    Robertson, J.R.2
  • 60
    • 0038356602 scopus 로고    scopus 로고
    • Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy
    • Vergote I, Robertson JFR, et al. Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy. Breast Cancer Res Treat 2003; 79:207-211.
    • (2003) Breast Cancer Res Treat , vol.79 , pp. 207-211
    • Vergote, I.1    Robertson, J.F.R.2
  • 61
    • 17144472154 scopus 로고    scopus 로고
    • Activity of exemestane in metastatic breast cancer after failure of nonsteroidal aromatase inhibitors: A phase II trial
    • Lønning PE, Bajetta E, Murray R, et al. Activity of exemestane in metastatic breast cancer after failure of nonsteroidal aromatase inhibitors: a phase II trial. J Clin Oncol 2000; 18:2234-2244.
    • (2000) J Clin Oncol , vol.18 , pp. 2234-2244
    • Lønning, P.E.1    Bajetta, E.2    Murray, R.3
  • 62
    • 0034891355 scopus 로고    scopus 로고
    • High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine therapy
    • Lønning PE, Taylor PD, Anker G, et al. High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine therapy. Breast Cancer Res Treat 2001; 67:111-116.
    • (2001) Breast Cancer Res Treat , vol.67 , pp. 111-116
    • Lønning, P.E.1    Taylor, P.D.2    Anker, G.3
  • 63
    • 9144270449 scopus 로고    scopus 로고
    • Adaptive hypersensitivity to estrogen: Mechanism for sequential responses to hormonal therapy in breast cancer
    • Santen RJ, Song RX, Zhang Z, et al. Adaptive hypersensitivity to estrogen: mechanism for sequential responses to hormonal therapy in breast cancer. Clin Cancer Res 2004; 10:337s-345s.
    • (2004) Clin Cancer Res , vol.10
    • Santen, R.J.1    Song, R.X.2    Zhang, Z.3
  • 64
    • 9144256614 scopus 로고    scopus 로고
    • Cross-talk between estrogen receptor and growth factor pathways as a molecular target for overcoming endocrine resistance
    • Schiff R, Massarweh SA, Shou J, et al. Cross-talk between estrogen receptor and growth factor pathways as a molecular target for overcoming endocrine resistance. Clin Cancer Res 2004; 10(suppl):331s-336s.
    • (2004) Clin Cancer Res , vol.10 , Issue.SUPPL.
    • Schiff, R.1    Massarweh, S.A.2    Shou, J.3
  • 65
    • 18944365812 scopus 로고    scopus 로고
    • Evaluation of fulvestrant in women with advanced breast cancer and progression on prior aromatase inhibitor therapy: A phase II trial of the North Central Cancer Treatment Group
    • Abstract, 409
    • Ingle JN, Rowland KM, Suman VJ, et al. Evaluation of fulvestrant in women with advanced breast cancer and progression on prior aromatase inhibitor therapy: a phase II trial of the North Central Cancer Treatment Group. Breast Cancer Res Treat 2004; 88(suppl 1):S38 (Abstract #409).
    • (2004) Breast Cancer Res Treat , vol.88 , Issue.SUPPL. 1
    • Ingle, J.N.1    Rowland, K.M.2    Suman, V.J.3
  • 66
    • 0035930095 scopus 로고    scopus 로고
    • Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17beta-estradiol
    • Song RX, Mor G, Naftolin F, et al. Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17beta-estradiol. J Natl Cancer Inst 2001; 93:1714-1723.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1714-1723
    • Song, R.X.1    Mor, G.2    Naftolin, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.