Use of levobupivacaine for the treatment of postoperative pain after thoracotomies

Minerva Anestesiologica

Volumn 71, Issue 6, 2005, Pages 347-351

  De Cosmo, G ^a   Mascia, A ^a   Clemente, A ^a   Congedo, E ^a   Aceto, P ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Levobupivacaine; Post thoracotomy pain; Thoracic epidural analgesia

Indexed keywords

BUPIVACAINE; LEVOBUPIVACAINE; LOCAL ANESTHETIC AGENT; MORPHINE; OPIATE DERIVATIVE; SUFENTANIL;

ANALGESIC ACTIVITY; ARTICLE; CARDIOTOXICITY; CONTINUOUS EPIDURAL ANESTHESIA; COUGHING; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG DOSE REGIMEN; DRUG ELIMINATION; DRUG HALF LIFE; DRUG POTENTIATION; ENANTIOMER; EPIDURAL SPACE; HUMAN; LOCAL ANESTHESIA; NAUSEA; NEUROTOXICITY; POSTOPERATIVE PAIN; PRURITUS; QUANTITATIVE ANALYSIS; THORACOTOMY; VISUAL ANALOG SCALE; VOMITING;

ANALGESIA, EPIDURAL; ANALGESIA, PATIENT-CONTROLLED; ANESTHETICS, LOCAL; BUPIVACAINE; HUMANS; PAIN, POSTOPERATIVE; THORACOTOMY;

EID: 21644488460     PISSN: 03759393     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Heath ML. Deaths after intravenous regional anaesthesia. BMJ 1982;285:913-4.
2. Albright GA. Cardiac arrest following regional anaesthesia with etidocaine or bupivacaine. Anesthesiology 1979;51:285-6.
3. Cristwood RW, Greaves JL. Levobupivacaine: a new safer long acting local anaesthetic agent. Expert Opin Invest Drug 1999;8:861-76.
4. Denson DD, Behbehani MM, Gregg RV. Enantiomer-specific effects of an intravenously administered arrythmogenic dose of bupivacaine on neurons of the nucleus tractus solitarius and the cardiovascular system in the anesthetized rat. Reg Anesth 1992;17:311-6.
5. Mazoit JX, Boico O, Samii K. Myocardial uptake of bupivacaine. Pharmacokinetics and pharmacodynamics of bupivacaine enantiomers in the isolated perfused rabbit heart. Anesth Analg 1993;77:477-82.
6. Bardsley H, Cristwood R, Baker H. A comparison of the cardiovascular effects of levobupivacaine and rac-bupivacaine following intravenous administration to healthy volunteers. Br J Pharmacol 1998;46:245-9.
7. Van F, Rolan PE, Brennan N. Differential effects of levobupivacaine and racemic bupivacaine on the EEG in volunteers (abstract). Region Anesth Pain Med 1998;23 Suppl:48.
8. Mc Cleellan KJ and Spencer C. Levobupivacaine. Drugs 1998;56:355-62.
9. Foser RH, Markham A. Levobupivacaine: a review of its pharmacology and its use as a local anesthetic. Drugs 2000;59:551-79.
10. Cox CR, Faccenda KA, Gilhooly C. Extradural S(-)-bupivacaine: comparison with racemic RS-bupivacaine. Br J Anaesth 1998;80:289-93.
11. Cox CR, Checketts MR, MackKenzie N. Comparison of S(-)-bupivacaine with racemic (RS)-bupivacaine in supraclavicular brachial plexus block. Br J Anaesth 1998;80:594-8.
12. Mc Lure HA, Rubin AP. Comparison of 0.75% levobupivacaine with 0.75% racemic bupivacaine for peribulbar anaesthesia. Anaesthesia 1998;53:1160-4.
13. Kingsnorth AN, Cummings CG, Bennett DH. Local anaesthesia in elective inguinal hernia repair: a randomised, double-blind study comparing the efficacy of levobupivacaine with racemic bupivacaine. Eur J Surg. 2002;168:391-6.
14. Warner DO. Preventing postoperative pulmonary complications. Anesthesiology 2000;92:1467-72.
15. Slinger PD. Pro: every postthoracotomy patient deserves thoracic epidural analgesia. J Cardiothorac Vasc Anesth 1999;13:350-4.
16. Warner DO, Warner MA, Ritman EL. Human chest wall function during epidural anesthesia. Anesthesiology 1996;85:761-73.
17. Kozian A, Schilling T, Hachenberg T. Non analgesic effects of thoracic epidural anaesthesia 2005;18:29-34.
18. Von Knorring J, Lepantalo J, Lindgren L, Lindfors O. Cardiac arrythmias and myocardial ischemia after thoracotomy for lung cancer Ann Thorac Surg 1992;53: 642-7.
19. Meissner A, Eckardt L, Kirchhof P. Effects of thoracic epidural anesthesia with and without autonomic nervous system blockade on cardiac monophasic action potentials and effective refractoriness in awake dogs. Anesthesiology 2001;95:132-8.
20. Weatley RG, Schug SA, Watson D. Safety and efficacy of postoperative epidural analgesia. Br J Anaesth 2001;87:47-61.
21. Hansdottir V, Wostenborghs R, Nordberg G. The pharmacokinetics of continous epidural sufentanil and bupivacaine infusions afte thoracotomy. Anesth Analg 1996;83:394-406.
22. Conacher ID, Paes ML, Jacobson L Phillips PD, Heaviside DW. Epidural analgesia following thoracic surgery. A review of two years' experiences. Anaesthesia 1983;38:546-51.
23. Neustein S, Kreitzer JM, Krellenstein D, Reich DL, Rapaport E, Cohen E. Pre-emptive epidural analgesia for thoracic surgery. Mt Sinai J Med 2002;69:101-4.