Analgesic and topical anti-inflammatory activity of Hypericum canariense L. and Hypericum glandulosum Ait.

Journal of Ethnopharmacology

Volumn 96, Issue 3, 2005, Pages 591-596

  Rabanal, R M ^a   Bonkanka, C X ^a   Hernandez Perez M ^a   Sanchez Mateo C C ^a  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

Author keywords

Analgesic activity; Hypericum canariense; Hypericum glandulosum; Mice; Topical anti inflammatory activity

Indexed keywords

ACETIC ACID; BUTANOL; HYPERICUM CANARIENSE EXTRACT; HYPERICUM EXTRACT; HYPERICUM GLANULOSUM EXTRACT; METHANOL; PHORBOL 13 ACETATE 12 MYRISTATE; UNCLASSIFIED DRUG; NONSTEROID ANTIINFLAMMATORY AGENT; PLANT EXTRACT;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; FEMALE; HYPERICUM; MALE; MOUSE; NONHUMAN; OTITIS; TAIL FLICK TEST; WRITHING TEST; ANIMAL; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; EAR; FLOWER; INFLAMMATION; ORAL DRUG ADMINISTRATION; PAIN; PHYTOTHERAPY; TAIL; TOPICAL DRUG ADMINISTRATION;

ANIMALIA; HYPERICUM; HYPERICUM CANARIENSE; HYPERICUM GLANDULOSUM;

ACETIC ACID; ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; EAR; FEMALE; FLOWERS; HYPERICUM; INFLAMMATION; MALE; MICE; PAIN; PHYTOTHERAPY; PLANT EXTRACTS; TAIL; TETRADECANOYLPHORBOL ACETATE;

EID: 21644455087     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2004.10.013     Document Type: Article

References (38)

1. Apaydin, S., Zeybek, U., Ince, I., Elgin, G., Karamenderes, C., Ozturk, B., Tuglular, I., 1999. Hypericum triquetrifolium Turra. extract exhibits antinociceptive activity in the mouse. Journal of Ethnopharmacology 67, 307-312.
2. Axarlis, S., Mentis, A., Demetzos, C., Mitaku, S., Skaltsounis, A.L., Marselos, M., Malamas, M., 1998. Antiviral in vitro activity of Hypericum perforation L. extract on the human cytomegalovirus (HCMV). Phytotherapy Research 12, 507-511.
3. Barnes, J., Anderson, L.A., Phillipson, J.D., 2001. St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties. Journal of Pharmacy and Pharmacology 53, 583-600.
4. Bombardelli, E., Morazzoni, P., 1995. Hypericum perforatum. Fitoterapia 66, 43-68.
5. Brenner, R., Azbel, V., Madhusoodanan, S., Pawlowska, M., 2000. Comparison of an extract of Hypericum (LI 160) and sertraline in the treatment of depression: a double-blind, randomized pilot study. Clinical Therapeutics 22, 411-419.
6. Butterweck, V., Wall, A., Liefländer-Wulf, U., Winterhoff, H., Nahrstedt, A., 1997. Effects of the total extract and fractions of Hypericum perforatum in animal assays for antidepressant activity. Pharmacopsychiatry 30, 117-124.
7. Cakir, A., Mavi, A., Yildirim, A., Duru, M.E., Harmandar, M., Kazaz, C., 2003. Isolation and characterization of antioxidant phenolic compounds from the aerial parts of Hypericum hyssopifolium L. by activity-guided fractionation. Journal of Ethnopharmacology 87, 73-83.
8. Calixto, J.B., Beirith, A., Ferreira, J., Santos, A.R.S., Filho, V.C., Yunes, R.A., 2000. Naturally occurring antinociceptive substances from plants. Phytotherapy Research 14, 401-418.
9. Carbon, R.P., O'Neill-Davis, L., Chang, J., Lewis, A.J., 1985. Modulation of mouse ear edema by cyclooxigenase and lipoxygenase inhibitors and other pharmacological agents. Agents and Actions 17, 197-204.
10. Collier, H.O.J., Dinneen, L.C., Johnson, C.A., Schneider, C., 1968. The abdominal constriction response and its suppression by analgesic drugs in the mouse. British Journal of Pharmacology 32, 295-310.
11. Couladis, M., Chinou, I.B., Tzakou, O., Petrakis, P.V., 2003. Composition and antimicrobial activity of essential oil of Hypericum rumeliacum subsp. apollinis (Boiss & Heldr.). Phytotherapy Research 17, 152-154.
12. Darias, V., Bravo, L., Barquín, E., Martín-Herrera, D., Fraile, C., 1986. Contribution to the ethnopharmacological study of the Canary Islands. Journal of Ethnopharmacology 15, 169-193.
13. Darias, V., Bravo, L., Rabanal, R., Sánchez Mateo, C., González Luis, R.M., Hernández Pérez, A.M., 1989. New contribution to the ethnopharmacological study of the Canary Islands. Journal of Ethnopharmacology 25, 77-92.
14. Daudt, R., von Poser, G.L., Neves, G., Rates, S.M.K., 2000. Screening for the antidepressant activity of some species of Hypericum from South Brazil. Phytotherapy Research 14, 344-346.
15. De Young, L.M., Kheifets, J.B., Ballaron, S.J., Young, J.M., 1989. Edema and cell infiltration in the phorbol ester-treated mouse ear are temporally separated and can be differentially modulated by pharmacologic agents. Agents and Actions 26, 335-341.
16. Guardia, T., Rotelli, A.E., Juárez, O., Pelzer, L.E., 2001. Anti-inflammatory properties of plant flavonoids. Effect of rutin, quercetin and hesperidin on adjuvant arthritis in rat. Il Farmaco 56, 683-687.
17. Flausino Jr., O.A., Zangrossi Jr., H., Salgado, J.V., Viana, M.B., 2002. Effects of acute and chronic treatment with Hypericum perforatum L. (LI 160) on different anxiety-related responses in rats. Pharmacology, Biochemistry and Behavior 71, 259-265.
18. Heilmann, J., Winkelmann, K., Sticher, O., 2003. Studies on the antioxidative activity of phloroglucinol derivatives isolated from Hypericum species. Planta Medica 69, 202-206.
19. Hernández-Pérez, M., Rabanal, R.M., de la Torre, M.C., Rodríguez, B., 1995. Analgesic, anti-inflammatory, antipyretic and haematological effects of aethiopinone, an o-naphtoquinone diterpenoid from Salvia aethiopis roots and two hemisynthetic derivatives. Planta Medica 61, 505-509.
20. Hernández-Pérez, M., Rabanal, R.M., 2002. Evaluation of the antiinflammatory and analgesic activity of Sideritis canariensis var. pannosa in mice. Journal of Ethnopharmacology 81, 43-47.
21. Just, M.J., Recio, M.C., Giner, R.M., Cuéllar, M.J., Máñez, S., Bilia, A.R., Ríos, J.L., 1998. Anti-inflammatory activity of unusual lupane saponins from Bupleurum fruticescens. Planta Medica 64, 404-407.
22. Mattace Raso, G., Pacilio, M., Di Carlo, G., Esposito, E., Pinto, L., Meli, R., 2002. In-vivo and in-vitro anti-inflammatory effect of Echinacea purpurea and Hypericum perforatum. Journal of Pharmacy and Pharmacology 54, 1379-1383.
23. Morikawa, K., Nonaka, M., Narahara, M., Torii, I., Kawagychi, K., Oyoshikawa, T., Kumazawa, Y., Morikawa, S., 2003. Inhibitory effect of quercetin on carrageenan-induced inflammation in rats. Life Sciences 74, 709-721.
24. Mukherjee, P.K., Verpoorte, R., Suresh, B., 2000. Evaluation of in-vivo wound healing activity of Hypericum patulum (family: Hypericaceae) leaf extract on different wound model in rats. Journal of Ethnopharmacology 70, 315-321.
25. Öztürk, Y., Aydin, S., Beis, R., Hüsnü Can Baser, K., 1996. Effects of Hypericum calycinum L. extract on the central nervous system in mice. Phytotherapy Research 10, 700-702.
26. Öztürk, B., Apaydin, S., Goldeli, E., Ince, I., Zeybek, U., 2002. Hypericum triquetrifolium Turra. extract exhibits antiinflammatory activity in the rat. Journal of Ethnopharmacology 80, 207-209.
27. Prado, B., Rabanal, R.M., Sánchez-Mateo, C.C., 2002. Evaluation of the central properties of several Hypericum species from the Canary Islands. Phytotherapy Research 16, 740-744.
28. Pérez de Paz, P.L., Hernández-Padron, C.E., 1999. Plantas medicinales o útiles en la flora canaria. In: Lemus, F. (Ed.), Aplicaciones populares. La Laguna, Spain, p. 115.
29. Rabanal, R.M., Arias, A., Prado, B., Hernández-Pérez, M., Sánchez-Mateo, C.C., 2002. Antimicrobial studies on three species of Hypericum from the Canary Islands. Journal of Ethnopharmacology 81, 287-292.
30. Ramabadran, K., Bansinath, M., Turndorf, H., Puig, M.M., 1989. Tail immersion test for the evaluation of a nociceptive reaction in mice. Methodological considerations. Journal of Pharmacological Methods 21, 21-31.
31. Rotelli, A.E., Guardia, T., Juárez, A.O., de la Rocha, N.E., Pelzer, L.E., 2003. Comparative study of flavonoids in experimental models of inflammation. Pharmacological Research 48, 601-606.
32. Sânchez-Mateo, C.C., Prado, B., Rabanal, R.M., 2002. Antidepressant effects of the methanol extract of several Hypericum species from the Canary Islands. Journal of Ethnopharmacology 79, 119-127.
33. Schulz, V., 2001. Incidence and clinical relevance of the interactions and side effects of Hypericum preparations. Phytomedicine 8, 152-160.
34. Schulz, V., 2002. Clinical trials with Hypericum extracts in patients with depression-results, comparisons, conclusions for therapy with antidepressant drugs. Phytomedicine 9, 468-474.
35. Srinivasan, K., Muruganandan, S., Lal, J., Chandra, S., Tandan, S.K., Raviprakash, V., Kumar, D., 2003. Antinoniceptive and antipyretic activities of Pongamia pinnata leaves. Phytotherapy Research 17, 259-264.
36. Tallarida, R.J., Murria, R.B., 1987. Manual of pharmacologic calculations with computer programs, second ed. Springer-Verlag, New York, pp. 110-134.
37. Trovato, A., Raneri, E., Kouladis, M., Tzakou, O., Taviano, M.F., Galeti, E.M., 2001. Anti-inflammatory and analgesic activity of Hypericum empetrifolium Willd (Guttiferae). Il Farmaco 56, 455-457.
38. Wagner, H., 1989. Search for new plant constituents with potential antiphlogistic and antiallergic activity. Planta Medica 55, 235-241.