Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase B

Biochemistry

Volumn 44, Issue 26, 2005, Pages 9339-9347

  Adler, Marc ^a   Bryant, Judi ^a   Buckman, Brad ^a   Islam, Imadul ^a   Larsen, Brent ^a   Finster, Silke ^a   Kent, Lorraine ^a   May, Karen ^a   Mohan, Raju ^a   Yuan, Shendong ^a   Whitlow, Marc ^a  

^a BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACIDS; CONFORMATIONS; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; HYDROGEN BONDS; PHENOLS; X RAYS;

ANTAGONISTS; EXOPEPTIDASES; PORCINE PANCREATIC CARBOXYPEPTIDASE B; X-RAY STRUCTURE;

SULFUR COMPOUNDS;

ANTIFIBRINOLYTIC AGENT; ARGININE; CARBOXYLIC ACID; CARBOXYPEPTIDASE B; EXOPEPTIDASE; FIBRINOLYTIC AGENT; GUANIDINE; THIOL REAGENT; ZINC;

ACUTE HEART INFARCTION; AMINO ACID SEQUENCE; ARTICLE; CHELATION; COMPLEX FORMATION; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG BINDING; DRUG CONFORMATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; HYDROGEN BOND; NONHUMAN; PANCREAS; PRIORITY JOURNAL; PROTEIN PURIFICATION; SWINE; X RAY DIFFRACTION;

ANIMALS; CARBOXYPEPTIDASE B; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; MODELS, MOLECULAR; PANCREAS; PROTEASE INHIBITORS; PROTEIN CONFORMATION; SULFHYDRYL COMPOUNDS; SWINE;

SUIDAE;

EID: 21644454105     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0501941     Document Type: Article

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