Identification of the major urinary metabolite of the highly reactive cyclopentenone isoprostane 15-A2t-isoprostane in vivo

Journal of Biological Chemistry

Volumn 280, Issue 26, 2005, Pages 25178-25184

  Milne, Ginger L ^a   Gao, Ling ^a   Porta, Alessio ^b   Zanoni, Giuseppe ^b   Vidari, Giovanni ^b   Morrow, Jason D ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; BIOMARKERS; BIOSYNTHESIS; ESTERIFICATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; KETONES; LIPIDS; LIVING SYSTEMS STUDIES; MASS SPECTROMETRY; NEUROLOGY; PHOSPHOLIPIDS; RADIOACTIVITY;

CYCLOPENTENONE ISOPROSTANES; ELECTROPHILIC LIPIDS; OXIDANT STRESS; URINARY METABOLITES;

METABOLITES;

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 4 HYDROXYNONENAL; BIOLOGICAL MARKER; CARBONYL DERIVATIVE; CYCLOPENTENONE DERIVATIVE; CYCLOPENTENONE ISOPROSTANE 15 A2T; ISOPROSTANE; LIPID; PHOSPHOLIPID; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DERIVATIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; ISOTOPE LABELING; MASS SPECTROMETRY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTAGLANDIN METABOLISM; PROSTAGLANDIN SYNTHESIS; QUANTITATIVE ANALYSIS; RAT; URINE LEVEL;

ACETYLCYSTEINE; ANIMALS; BIOLOGICAL MARKERS; CARBON; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOPENTANES; DINOPROST; ISOPROSTANES; LIGANDS; MALE; MASS SPECTROMETRY; MODELS, CHEMICAL; PROSTAGLANDINS; RATS; RATS, SPRAGUE-DAWLEY; SCINTILLATION COUNTING; SULFOXIDES; TIME FACTORS;

RODENTIA;

EID: 21644439706     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M502891200     Document Type: Article

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