Accumulation of diacylglycerol in the chlamydia inclusion vacuole: Possible role in the inhibition of host cell apoptosis

Journal of Biological Chemistry

Volumn 280, Issue 26, 2005, Pages 25210-25215

  Tse, Shirley M L ^a,b   Mason, David ^a,b   Botelho, Roberto J ^a,b   Chiu, Basil ^c   Reyland, Mary ^d   Hanada, Kentaro ^e   Inman, Robert D ^c   Grinstein, Sergio ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d UNIVERSITY OF COLORADO   (United States)

^e NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; MITOCHONDRIA; PATHOGENS; PRO-APOPTOTIC EFFECTS;

CELLS; ENZYME INHIBITION; ENZYMES; FLUORESCENCE; LIPIDS; METABOLISM;

GLYCEROL;

DIACYLGLYCEROL; PROTEIN KINASE C DELTA;

APOPTOSIS; ARTICLE; CELL COMPARTMENTALIZATION; CELL INCLUSION; CELL NUCLEUS; CHLAMYDIA; CONTROLLED STUDY; ENZYME ACTIVE SITE; FLUORESCENCE; HOST CELL; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; LIPID METABOLISM; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SURVIVAL;

ACETOPHENONES; ANIMALS; APOPTOSIS; BENZOPYRANS; BINDING SITES; CATALYTIC DOMAIN; CELL LINE; CELL NUCLEUS; CHLAMYDIA; CHLAMYDIA INFECTIONS; CRICETINAE; DIGLYCERIDES; HELA CELLS; HUMANS; LIPIDS; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; PLASMIDS; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS; TRANSFECTION; VACUOLES;

CHLAMYDIA;

EID: 21644436126     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M501980200     Document Type: Article

References (34)

1. Fan, T., Lu, H., Hu, H., Shi, L., McClarty, G. A., Nance, D. M., Greenberg, A. H., and Zhong, G. (1998) J. Exp. Med. 187, 487-496
2. Dean, D., and Powers, V. C. (2001) Infect. Immun. 69, 2442-2447
3. Fischer, S. F., Vier, J., Kirschnek, S., Klos, A., Hess, S., Ying, S., and Häcker, G. (2004) J. Exp. Med. 200, 905-916
4. Li, L., Lorenzo, P. S., Bogi, K., Blumberg, P. M. and Yuspa, S. H. (1999) Mol. Cell. Biol. 19, 8547-8558
5. Majumder, P. K., Pandey, P., Sun, X., Cheng, K., Datta, R., Saxena, S., Kharbanda, S., and Kufe, D. (2000) J. Biol. Chem. 275, 21793-21796
6. Matassa, A. A., Carpenter, L., Biden, T. J., Humphries, M. J., and Reyland, M. E. (2001) J. Biol. Chem. 276, 29719-29728
7. Denning, M. F., Wang, Y., Tibudan, S., Alkan, S., Nickoloff, B. J., and Qin, J. Z. (2002) Cell Death Differ. 9, 40-52
8. Bharti, A., Kraeft, S. K., Gounder, M., Pandey, P., Jin, S., Yuan, Z. M., Lees-Miller, S. P., Weichselbaum, E., Weaver, D., Chen, L. B., Kufe, D., and Kharbanda, S. (1998) Mol. Cell. Biol. 18, 6719-6728
9. Cross, T., Griffiths, G., Deacon, E., Sallis, R., Gough, M., Watters, D., and Lord, J. M. (2000) Oncogene 19, 2331-2337
10. Kanada, K., Nishijima, M., Fujita, T., and Kobayashi, S. (2000) Biochem. Pharmacol. 59, 1211-1216
11. DeVries, T. A., Neville, M. C., and Reyland, M. E. (2002) EMBO J. 21, 6050-6060
12. Martelli, A. M., Zweyer, M., Ochs, R. L., Tazzari, P. L., Tabellini, G., Narducci, P., and Bortul, R. (2001) J. Cell. Biochem. 82, 634-646
13. Burden, D. A., Kingma, P. S., Froelich-Ammon, S. J., Bjornsti, M. A., Patchan, M. W., Thompson, R. B., and Osheroff, N. (1996) J. Biol. Chem. 271, 29238-29244
14. Kaufmann, S. H. (1998) Biochim. Biophys. Acta 1400, 195-211
15. Reyland, M. E., Anderson, S. M., Matassa, A. A., Barzen, K. A., and Quissell, D. O. (1999) J. Biol. Chem. 274, 19115-19123
16. Bromberg, K. D., Burgin, A. B., and Osheroff, N. (2003) J. Biol. Chem. 278, 7406-7412
17. Gschwendt, M., Muller, H. J., Kielbassa, K., Zang, R., Kittstein, W., Rincke, G., and Marks, F. (1994) Biochem. Biophys. Res. Commun. 199, 93-98
18. Ruvolo, P. P., Deng, X., Carr, B. K., and May, W. S. (1998) J. Biol. Chem. 273, 25436-25442
19. Gubina, E., Rinaudo, M. S., Szallasi, Z., Blumberg, P. M., and Mufson, R. A. (1998) Blood 91, 823-829
20. Jamieson, L., Carpenter, L., Biden, T. J., and Fields, P. (1999) J. Biol. Chem. 274, 3927-3930
21. Perego, C., Porro, C., and La Porta, C. A. (2002) Biochem. Biophys. Res. Commun. 294, 127-131
22. Shultz, A., Ling, M., and Larsson, C. (2004) J. Biol. Chem. 279, 31750-31760
23. Stahelin, R. V., Digman, M. A., Medkova, M., Ananthanarayanan, B., Rafter, J. D., Melowic, H. R., and Cho, W. (2004) J. Biol. Chem. 279, 29501-29512
24. Stahelin, R. V., Digman, M. A., Medkova, M., Ananthanarayanan, B., Melowic, H. R., Rafter, J. D., and Cho, W. (2005) J. Biol. Chem. 280, 19784-19793
25. Baron, C. L., and Malhotra, V. (2002) Science 295, 325-328
26. Kajimoto, T., Ohmori, S., Shira, I. Y., Sakai, N., and Saito, N. (2001) Mol. Cell. Biol. 21, 1769-1783
27. Hackstadt, T., Rockey, D. D., Heinzen, R. A., and Scidmore, M. A. (1996) EMBO J. 15, 964-977
28. Scidmore, M. A., Fischer, E. R., and Hackstadt, T. (1996) J. Cell Biol. 134, 363-374
29. Hackstadt, T., Scidmore, M. A., and Rockey, D. D. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4877-4881
30. Ono, Y., Fujii, T., Igarashi, K., Kuno, T., Tanaka, C., Kikkawa, U., and Nishizuka, Y. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 4868-4871
31. Burns, D. J., and Bell, R. M. (1991) J. Biol. Chem. 266, 18330-18338
32. Sweeney, D. A., Siddhanta, A., and Shields, D. (2002) J. Biol. Chem. 277, 3030-3039
33. Merrill, A. H., van Echten, G., Wang, E., and Sandhoff, K. (1993) J. Biol. Chem. 268, 27299-27306
34. Hausser, A., Link, G., Bamberg, L., Burzlaff, A., Lutz, S., Pfizenmaier, K., and Johannes, F. J. (2002) J. Cell Biol. 156, 65-74