Determination of percutaneous absorption by in vitro techniques

Journal of Toxicology - Cutaneous and Ocular Toxicology

Volumn 20, Issue 4, 2001, Pages 423-427

  Bronaugh, Robert L ^a   Hood, Harolyn L ^a,b   Kraeling, Margaret E K ^a   Yourick, Jeffrey J ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 21544482015     PISSN: 07313829     EISSN: None     Source Type: Journal    
DOI: 10.1081/CUS-120001867     Document Type: Article

References (11)

1. Bronaugh, R.L.; Stewart, R.F.; Congdon, E.R. Methods for In Vitro Percutaneous Absorption Studies. II: Comparison of Human and Animal Skin. Toxicol. Appl. Pharmacol. 1982, 62, 481-488.
2. Collier, S.W.; Sheikh, N.M.; Sakr, A.; Lichtin, J.L.; Stewart, R.F.; Bronaugh, R.L. Maintenance of Skin Viability During In Vitro Percutaneous Absorption/Metabolism Studies. Toxicol. Appl. Pharmacol. 1989, 99, 522-533.
3. Chu, I.; Dick, R.; Bronaugh, R.L.; Tryphonas, L. Skin Reservoir Formation and Bioavailability of Dermally Administered Chemicals in Hairless Guinea Pigs. Food Chem. Toxicol. 1996, 34, 267-276.
4. Hood, H.L.; Wickett, R.R.; Bronaugh, R.L. The In Vitro Percutaneous Absorption of the Fragrance Ingredient Musk Xylol. Food Chem. Toxicol. 1996, 34, 483-488.
5. Bronaugh, R.L.; Stewart, R.F. Methods for In Vitro Percutaneous Absorption Studies. III: Hydrophobic Compounds. J. Pharm. Sci. 1984, 73, 1255-1258.
6. Ng, K.M.E.; Chu, I.; Bronaugh, R.L.; Franklin, C.A.; Somers, D.A. Percutaneous Absorption and Metabolism of Pyrene, Benzo[a]pyrene and Di-(2-ethylhexyl) phthalate: Comparison of In Vitro and In Vivo Results in the Hairless Guinea Pig. Toxicol. Appl. Pharmacol. 1992, 155, 216-223.
7. Nathan, D.; Sakr, A.; Lichtin, J.L.; Bronaugh, R.L. In Vitro Skin Absorption and Metabolism of Benzoic Acid, p-Aminobenzoic Acid, and Benzocaine in the Hairless Guinea Pig. Pharm. Res. 1990, 7, 1147-1151.
8. Boehnlein, J.; Sakr, A.; Lichtin, J.L.; Bronaugh, R.L. Metabolism of Retinyl Palmitate to Retinol (Vitamin A) in Skin During Percutaneous Absorption. Pharm. Res. 1994, 11, 1155-1159.
9. Kraeling, M.E.K.; Lipicky, R.J.; Bronaugh, R.L. Metabolism of Benzocaine During Percutaneous Absorption in the Hairless Guinea Pig: Acetylbenzocaine Formation and Activity. Skin Pharmacol. 1996, 9, 221-230.
10. Bronaugh, R.L.; Stewart, R.F. Methods for In Vitro Percutaneous Absorption Studies. VI: Preparation of the Barrier Layer. J. Pharm. Sci. 1986, 76, 487-491.
11. Bronaugh, R.L.; Congdon, E.R.; Scheuplein, R.J. The Effect of Cosmetic Vehicles on the Penetration of N-Nitrosodiethanolamine Through Excised Human Skin. J. Investig. Dermatol. 1981, 76, 94-96.