Preventive treatment of nephrolithiasis with alkali citrate - A critical review

Urological Research

Volumn 33, Issue 2, 2005, Pages 73-79

  Mattle, D ^a   Hess, B ^b,c  

^a Regional Hospital   (Switzerland)

^b Hospital Zimmerberg   (Switzerland)

^c KLINIK IM PARK   (Switzerland)

Author keywords

Alkali citrate treatment; Calcium oxalate; Citrate; Nephrolithiasis; Uric acid; Urolithiasis

Indexed keywords

ALKALI; ALKALI CITRATE; CALCIUM OXALATE; CITRATE POTASSIUM; CITRATE POTASSIUM SODIUM; CITRIC ACID; MAGNESIUM CITRATE; MAGNESIUM DERIVATIVE; MAGNESIUM GLYCINE; MAGNESIUM OXIDE; PLACEBO; POTASSIUM CHLORIDE; POTASSIUM DERIVATIVE; POTASSIUM MAGNESIUM CITRATE; UNCLASSIFIED DRUG; URIC ACID;

ABDOMINAL DISEASE; BLOATING; DIARRHEA; ERUCTATION; HUMAN; METHODOLOGY; NEPHROLITHIASIS; PRIORITY JOURNAL; RECURRENT DISEASE; REVIEW; STONE DISSOLUTION; STONE FORMATION; UROLITHIASIS;

ALKALIES; CITRIC ACID; HUMANS; URINARY CALCULI;

EID: 21544456652     PISSN: 03005623     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00240-005-0464-8     Document Type: Review

References (56)

1. Pak CY (1991) Citrate and renal calculi: new insights and future directions. Am J Kidney Dis 17: 420
2. Erwin DT, Kok DJ, Alam J, Vaughn J, Coker O, Carriere BT et al. (1994) Calcium oxalate stone agglomeration reflects stone-forming activity: citrate inhibition depends on macxro-molecules larger than 30 kilodalton. Am J Kidney Dis 24: 893
3. Hess B, Jordi S, Zipperle L, Ettinger E, Giovanoli R (2000) Citrate determines calcium oxalate crystallization kinetics and crystal morphology - studies in presence of Tamm-Horsfall protein of a healthy subject and a severely recurrent calcium stone former. Nephrol Dial Transplant 15: 366
4. Hamm LL, Hering-Smith KS (2002) Pathophysiology of hypocitraturic nephrolithiasis. Endocrinol Metab Clin North Am 31: 885
5. Hess B, Michel R, Takkinen R, Ackermann D, Jaeger P (1994) Risk factors for low urinary citrate in calcium nephrolithiasis: low vegetable fibre intake and low urine volume to be added to the list. Nephrol Dial Transplant 9: 642
6. Simpson DP (1983) Citrate excretion: a window on renal metabolism. Am J Physiol 244: F223
7. Churchill DN (1987) Medical treatment to prevent recurrent calcium urolithiasis. Mineral Eletrolyte Metab 13: 294
8. Wang Y-H, Grenabo L, Hedelin H, Pettersson S (1994) The effects of sodium citrate and oral potassium citrate on urease-induced crystallization. Br J Urol 74: 409
9. Kollwitz AA (1966) Die Behandlung und Prophylaxe von Harnsä uresteinen der Niere durch orale Alkalisierung. Dtsch Med Wochenschr 28: 1257
10. Uhlir K (1970) The peroral dissolution of renal calculi. J Urol 104: 239
11. Petritsch PH (1977) Uric acid calculi: results of conservative treatment. Urology 10: 536
12. Bach D, Hesse A, Strenge A, Vahlensieck W (1980) Harnstein-Prophylaxe mit einer Benzbromaron-Zitrat-Kombination. Fortschr Med 44: 1752
13. Butz M (1982) Oxalatsteinprophylaxe durch Alkali-Therapie. Urologe A 21: 142
14. Pak CY, Sakhaee K, Fuller CJ (1983) Physiological and physicochemical correction and prevention of calcium stone formation by potassium citrate therapy. Trans Assoc Am Physicians 96: 294
15. Nicar MJ, Peterson R, Pak CY (1984) Use of potassium citrate as potassium supplement during thiazide therapy of calcium nephrolithiasis. J Urol 131: 430
16. Pak CY, Peterson R, Sakhaee K, Fuller C, Preminger G, Reisch J (1985) Correction of hypocitraturia and prevention of stone formation by combined thiazide and potassium citrate therapy in thiazide-unresponsive hypercalciuric nephrolithiasis. Am J Med 79: 284
17. Pak CY, Fuller C, Sakhaee K, Preminger GM, Britton F (1985) Long-term treatment of calcium nephrolithiasis with potassium citrate. J Urol 134: 11
18. Preminger GM, Peterson R, Peters PC, Pak CY (1985) The current role of medical treatment of nephrolithiasis: the impact of improved techniques of stone removal. J Urol 134: 6
19. Pak CY, Fuller C (1986) Idiopathic hypocitraturic calcium-oxalate nephrolithiasis successfully treated with potassium citrate. Ann Int Med 104: 33
20. Pak CY, Peterson R (1986) Successful treatment of hyperuricosuric calcium oxalate nephrolithiasis with potassium citrate. Arch Intern Med 146: 863
21. Pak CY, Sakhaee K, Fuller C (1986) Successful management of uric acid nephrolithiasis with potassium citrate. Kidney Int 30: 422
22. Nicar MJ, Hsu MC, Fetner C (1986) Urinary response to oral potassium citrate therapy for urolithiasis in a private practice setting. Clin Ther 8: 219
23. Higashihara E, Nutahara K, Niijima T (1988) Renal hypercalciuria and metabolic acidosis associated with medullary sponge kidney: effect of alkali therapy. Urol Res 16: 95
24. Hauser W, Frick J, Kunit G (1990). Alkali citrate for preventing recurrence of calcium oxalate stones. Eur Urol 17: 248
25. Lindberg J, Harvey J, Pak CY (1990) Effect of magnesium citrate and magnesium oxide on the crystallization of calcium salts in urine: changes produced by food-magnesium interaction. J Urol 143: 248
26. Rodman JS (1991) Prophylaxis of uric acid stones with alternate day doses of alkaline potassium salts. J Urol 145: 97
27. Herrmann U, Schwille PO, Schwarzlaender H, Berger I, Hoffmann G (1992) Citrate and recurrent idiopathic calcium urolithiasis: a longitudinal pilot study on the metabolic effects of oral potassium sodium citrate administered as short-, medium- and long-term to male stone patients (version I). Urol Res 20: 347
28. Schwille PO, Herrmann U, Wolf C, Berger I, Meister R (1992) Citrate and recurrent idiopathic calcium urolithiasis: a longitudinal pilot study on the metabolic effects of oral potassium citrate administered over the short-, medium- and long-term medication of male stone patients (version II). Urol Res 20: 145
29. Pak CY, Koenig K, Khan R, Haynes S, Padalino P (1992) Physicochemical action of potassium-magnesium citrate in nephrolithiasis. J Bone Miner Res 7: 281
30. Ito H, Suzuki F, Yamaguchi K, Nishikawa Y, Kotake T (1992) Reduction of urinary oxalate by combined calcium and citrate administration without increase in urinary calcium oxalate stone formers. Clin Nephrol 37: 14
31. Berg C, Larsson L, Tiselius HG (1992) The effects of a single evening dose of alkaline citrate on urine composition and calcium stone formation. J Urol 148: 979
32. Khanniazi MK, Khanam A, Naqvi SA, Sheikh MA (1993) Study of potassium citrate treatment of crystalluric nephrolithiasis. Biomed Pharmacother 47: 25
33. Wabner CL, Pak CY (1993) Effect of orange juice consumption on urinary stone risk factors. J Urol 149: 1405
34. Abdulhadi MH, Hall PM, Streem SB (1993) Can citrate therapy prevent nephrolithiasis? Urology 41: 221
35. Barcelo P, Wuhl O, Servitge E, Rousaud A, Pak CY (1993) Randomized double-blind study of potassium citrate in idiopathic hypocitraturic calcium nephrolithiasis. J Urology 150: 1761
36. Kocvara R, Louzensky G, Tuikova J (1994) Development of metaphylaxis in calcium urolithiasis: a restriction of conventional drug therapy. Int Urol Nephrol 26: 269
37. Hofbauer J, Hobarth K, Szabo N, Marberger M (1994) Alkali citrate prophylaxis in idiopathic recurrent calcium oxalate urolithiasis - a prospective randomized study. Br J Urol 73: 362
38. Cicerello E, Merlo F, Gambaro G, Maccatrozzo L, Fandella A, Baggio B et al. (1994) Effect of alkaline citrate therapy on clearance of residual renal stone fragments after extracorporeal shock wave lithotripsy in sterile calcium and infection nephrolithiasis patients. J Urol 151: 5
39. Fine JK, Pak CY, Preminger GM (1995) Effect of medical management and residual fragments on recurrent stone formation following shock wave lithotripsy. J Urol 153: 27
40. Whalley NA, Meyers AM, Martins M, Margolius LP (1996) Long-term effects of potassium citrate therapy on the formation of new stones in groups of recurrent stone formers with hypocitraturia. Br J Urol 78: 10
41. Ettinger B, Pak CY, Citron JT, Thomas C, Adams-Huet B, Vangessel A (1997) Potassium-magnesium citrate is an effective prophylaxis against recurrent calcium oxalate nephrolithiasis. J Urol 158: 2069
42. Grases F, Conte A, March JG, Garcia-Ferragut L (1998) Evolution of lithogenic urinary parameters with a low dose potassium citrate treatment. Int Urol Nephrol 30: 1
43. Fuselier HA, Moore K, Lindberg J, Husserl FE, Cole FE, Kok DJ et al. (1998) Agglomeration inhibition reflected stone forming activity during long-term potassium citrate therapy in calcium stone formers. Urology 52: 988
44. Lee YH, Huang WC, Tsai JY, Huang JK (1999) The efficacy of potassium citrate based medical prophylaxis for preventing upper urinary tract calculi: a midterm follow-up study. J Urol 161: 1453
45. Ruml LA, Pak CY (1999) Effect of potassium magnesium citrate on thiazide-induced hypokalemia and magnesium loss. Am J Kidney Dis 34: 107
46. Premgamone A, Sriboonlue P, Disatapornjaroen W, Maskasem S, Sinsupan N, Apinives C (2001) A long-term study on the efficacy of a herbal plant, orthosiphon grandiflorus, and sodium potassium citrate in renal calculi treatment. Southeast Asian J Trop Med Public Health 32: 654
47. Soygür T, Akbay A, Kupeli S (2002) Effect of potassium citrate therapy on stone recurrence and residual fragments after shockwave lithotripsy in lower caliceal calcium oxalate urolithiasis: a randomized controlled trial. J Endourol 16: 149
48. Pak CY, Heller HJ, Pearle MS, Odvina CV, Poindexter JR, Peterson RD (2003) Prevention of stone formation and bone loss in absorptive hypercalciuria by combined dietary and pharmacological interventions. J Urol 169: 465
49. Siener R, Glatz S, Nicolay C, Hesse A (2003) Prospective study on the efficacy of a selective treatment and risk factors for relapse in recurrent calcium oxalate stone patients. Eur Urol 44: 467
50. Mardis HK, Parks JH, Muller G, Ganzel K, Coe FL (2004) Outcome of metabolic evaluation and medical treatment for calcium nephrolithiasis in a private urological practice. J Urol 171: 85
51. Jaipakdee S, Prasongwatana V, Premgamone A, Reungjui S, Toshukhowong P, Tungsanga K et al. (2004) The effects of potassium and magnesium supplementations on urinary risk factors of renal stone patients. J Med Assoc Thai 87: 255
52. Pearle MS, Roehrborn CG, Pak CY (1999) Meta-analysis of randomized trials for medical prevention of calcium oxalate nephrolithiasis. J Endourol 13: 679
53. Hesse A, Brändle E, Wilbert D, Köhrmann K-U, Alken P (2003) Study on the prevalence and incidence of urolithiasis in Germany comparing the years 1979 vs 2000. Eur Urol 44: 709
54. Stamatelou KK, Francis ME, Jones CA, Nyberg LM, Curhan GC (2003) Time trends in reported prevalence of kidney stones in the United States: 1976-1994. Kidney Int 63: 1817
55. Shekarriz B, Stoller ML (2002) Cystinuria and other noncalcareous calculi. Endocrinol Metab Clin N Am 31: 951
56. Kessler T, Hesse A (2000) Cross-over study of the influence of bicarbonate-rich mineral water on urinary composition in comparison with sodium potassium citrate in healthy subjects. Br J Nutr 84: 865