Is hafnium a valid surrogate for plutonium for biochemical and biokinetic studies in vivo?

Chemical Speciation and Bioavailability

Volumn 10, Issue 3, 1998, Pages 107-113

  Gillis, Tonya M ^a   Taylor, David M ^a   Williams, David R ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Hafnium; Plutonium surrogate

Indexed keywords

EID: 21544444196     PISSN: 09542299     EISSN: None     Source Type: Journal    
DOI: 10.3184/095422998782775781     Document Type: Article

References (13)

1. Allinson, G. D., Brown, D. S. and Novo-Gradac, K. J. 1990. MINTEQA2, a geochemical assessment model for environ-mental systems: Version 3, Environmental Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Athens, G A, USA.
2. Duffield, J. R. and Williams, D. R. 1986. The environmental chemistry of radioactive waste disposal. Chem. Soc. Rev., 15, 291-307
3. Duffield, J. R., Raymond, D. P. and Williams, D. R. 1987. Complexation of plutonium and thorium in aqueous environments. Inorg. Chim. Acta, 140, 369-372.
4. Duffield, J. R. and Taylor, D. M. 1987. A spectroscopic study of the binding of plutonium(IV) and its chemical analogues to transferrin. Inorg. Chim. Acta, 140, 365-367.
5. Geckeis, H., Klenze, R. and Kim, J. I. 1997. Solid-water interface reactions of actinides and homologues: sorption onto mineral surfaces. (Paper T4-B1 presented at Actinides ‘97, Baden-Baden, September 1997).
6. Gillis, T. M. 1997. Chemical speciation and the identification of actinide analogues. PhD thesis, University of Wales, Cardiff.
7. Gillis, T.M., Taylor, D. M. and Williams, D. R. 1998. Measurement of the formation constants for Hf(IV) complexes with oxalate and citrate. In preparation.
8. Shannon, R. D. 1976. Revised effective ionic radii and systematic studies of interatomic distances in halides and chalconides. Acta Crystallog., A32, 751-767.
9. Taylor, D. M. 1991. Acceleration of the natural rate of elimi-nation of transuranium elements from the mammalian body. In: Freeman, A. J. and Keller, C (eds.) Handbook on the Physics and Chemistry of the Actinides, Elsevier Science, Amsterdam, Chapter 11, pp. 533-549.
10. Taylor, D. M., Lehmann, M., Planas-Bohne, F. and Seidel, A. 1983. The Metabolism of radiohafnium in rats and hamsters: A possible analog of plutonium for metabolic studies, Radiat. Res. 95, 339-358.
11. Taylor, D. M., Seidel, A. and Doerfel, H. 1985. The metabolism of radiohafnium in marmosets and hamsters. Int. J. Radiat. Biol. 12, 387-391.
12. Taylor, D. M. 1998. The bioinorganic chemistry of actinides in blood. J. Alloys. Cmpds. 271-273, 6-10.
13. Yule, L. and Taylor, D. M. 1986. Studies of the chemical forms of plutonium and hafnium in an in vitro model of the human gastrointestinal tract. Unpublished observations.