Histopathologic findings after treatment with different oxidosqualene cyclase (OSC) inhibitors in hamsters and dogs

Experimental and Toxicologic Pathology

Volumn 57, Issue 1, 2005, Pages 29-38

  Funk, J ^a   Landes, C ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Dog; Hamster; Histopathology; Oxidosqualene cyclase (OSC) inhibitors; Subacute and subchronic toxicity

Indexed keywords

ENZYME INHIBITOR; OXIDOSQUALENE CYCLASE INHIBITOR; RO 0714565; RO 0717625; RO 0730574; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE LESION; BONE PLATE; CATARACT; CELL DEGENERATION; CELL HYPERPLASIA; CONTROLLED STUDY; DOG; ENZYME INHIBITION; EPIDIDYMIS; EPITHELIUM; EYE; EYE INJURY; FEMALE; FORESTOMACH; GERM CELL; HAMSTER; HISTOPATHOLOGY; HYPERKERATOSIS; INFLAMMATION; LENS; LONG BONE; MALE; NONHUMAN; OLIGOSPERMIA; OSSIFICATION; PROSTATE; RICKETS; SEMINAL VESICLE; SKIN; SQUAMOUS CELL; TESTIS; TESTIS ATROPHY; TOXICITY TESTING; TRABECULAR BONE;

CANIS FAMILIARIS; CRICETINAE; TRABECULA;

EID: 21544438213     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2005.02.006     Document Type: Article

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