Effective methimazole dose for childhood Grave's disease and use of free triiodothyronine combined with concurrent thyroid-stimulating hormone level to identify mild hyperthyroidism and delayed pituitary recovery

Journal of Pediatric Endocrinology and Metabolism

Volumn 18, Issue 6, 2005, Pages 597-602

  Slyper, Arnold H ^a   Wyatt, David ^b   Boudreau, Christian ^b  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Children; Free T3; Graves' disease; Methimazole

Indexed keywords

LIOTHYRONINE; THIAMAZOLE; THYROTROPIN;

ADOLESCENT; ANALYSIS OF VARIANCE; ARTICLE; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; DISEASE SEVERITY; DRUG MEGADOSE; FEMALE; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; GRAVES DISEASE; HORMONE RELEASE; HUMAN; HYPERTHYROIDISM; HYPOPHYSIS DISEASE; INTOXICATION; LOW DRUG DOSE; MALE; RETROSPECTIVE STUDY; STATISTICAL SIGNIFICANCE; THYROID FUNCTION TEST;

EID: 21444458311     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.2005.18.6.597     Document Type: Article

References (13)

1. Antithyroid agents. Methimazole. The AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists Inc., 2003; 3074-3075.
2. Dallas JS, Foley TP. Thyromegaly. In: Lifshitz F, ed. Pediatric Endocrinology, 3rd Ed. New York: Marcel Dekker Inc., 1996; 383-389.
3. Bitton RN, Wexler C. Free triiodothyronine toxicosis: a distinct entity. Am J Med 1990; 88: 531-533.
4. Simons RJ, Manni A. Free triiodothyronine toxicosis in a patient with multinodular goiter. Am J Med 1990; 88: 689-692.
5. 3) toxicosis. Am J Med 1994; 96: 229-234.
6. Root AW. Free triiodothyronine toxicosis in two adolescents. J Pediatr 1994; 124: 276-278.
7. Neter J, Kutner MH, Nachtschiem CJ, Wasserman W. Applied Linear Statistical Models, 4th Ed. Boston, MA: McGraw-Hill/Irwin, 1996; 1184-1194.
8. O'Malley BP, Rosenthal FD, Northover BJ, Jennings PE, Woods KL. Higher than conventional doses of carbimazole in the treatment of thyrotoxicosis. Clin Endocrinol (Oxf) 1988; 29: 281-288.
9. Messina M, Milani P, Gentile L, Monaco A, Brossa C, Porta M, Camanni F. Initial treatment of thyrotoxic Graves' disease with methimazole: a randomized trial comparing different dosages. J Endocrinol Invest 1987; 10: 291-295.
10. Page SR, Sheard CE, Herbert M, Hopton M, Jeffcoate WJ. A comparison of 20 or 40 mg per day of carbimazole in the initial treatment of hyperthyroidism. Clin Endocrinol (Oxf) 1996; 45: 511-516.
11. Uy HL, Reasner CA, Samuels MH. Pattern of recovery of the hypothalamic-pituitary-thyroid axis following radioactive iodine therapy in patients with Graves' disease. Am J Med 1995; 99: 173-179.
12. Albert SG, Goodgold HM, Chehade J, Kim J. Delayed recovery of thyrotropin responsiveness after radioactive iodine therapy for hyperthyroidism. Am J Med Sci 2000; 319: 376-379.
13. Brownlie BE, Legge HM. Thyrotropin results in euthyroid patients with a past history of hyperthyroidism. Acta Endocrinol 1990; 122: 623-627.