Mycophenolate mofetil may protect against Pneumocystis carinii pneumonia in renal transplanted patients

Revista do Instituto de Medicina Tropical de Sao Paulo

Volumn 47, Issue 3, 2005, Pages 143-145

  Azevedo, Luiz Sergio ^a   Castro, Maria Cristina R ^a   Paula, Flavio J ^a   Ianhez, Luiz Estevam ^a   David Neto, Elias ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Immunosuppression; Kidney transplantation; Mycophenolate mofetil; Pneumocystis carinii; Pneumonia

Indexed keywords

AZATHIOPRINE; COTRIMOXAZOLE; CYCLOSPORIN A; DEXAMETHASONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; TACROLIMUS;

ARTICLE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; PNEUMOCYSTIS CARINII; PNEUMOCYSTIS PNEUMONIA; PROPHYLAXIS; PROTECTION;

EID: 21444449502     PISSN: 00364665     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0036-46652005000300005     Document Type: Article

References (10)

1. BRANTEN, A.J.W.; BECKERS, P.J.A.; TIGGELER, R.G.W.L. & HOITSMA, A.J. - Pneumocystis carinii pneumonia in renal transplant recipients. Nephrol. Dial. Transplant., 10: 1194-1197, 1995.
2. EBPG EXPERT GROUP ON RENAL TRANSPLANTATION - European best practice guidelines for renal transplantation. Nephrol. Dial. Transplant., 17: 36-52, 2002.
3. EUROPEAN MYCOPHENOLATE MOFETIL COOPERATIVE STUDY GROUP - Placebo controlled study of mycophenolate mofetil combined with cyclosporine and corticosteroids for prevention of acute rejection. Lancet, 345: 1321-1325, 1995.
4. GORDON, S.M.; LAROSA, S.P.; KALMADI, S. et al. - Should prophylaxis for Pneumocystis carinii pneumonia in solid organ transplant recipients ever be discontinued? Clin. infect. Dis., 28: 240-246, 1999.
5. IANHEZ, L.E. & SABBAGA, E. - Infecção pós-transplante renal. Rev. Hosp. Clin. Fac. Med. S. Paulo, 34: 84-87, 1979.
6. MORRIS, A.; BEARD, C.B. & HUANG, L. - Update on the epidemiology and transmission of Pneumocystis carinii. Microbes Infect., 4: 95-103, 2002.
7. O'GARA, M.J.; LEE, C.H.; WEINBERG, G.A.; NOTT, J.M. & QUEENER, S.F. - IMP dehydrogenase from Pneumocystis carinii as a potential drug target. Antimicrob. Agents Chemother., 41: 40-48, 1997.
8. OZ, H.S. & HUGHES, W.T. - Novel anti-Pneumocystis carinii effects of the immunosuppressant mycophenolate mofetil in contrast to provocative effects of tacrolimus, sirolimus and dexamethasone. J. infect. Dis., 175: 901-904, 1997.
9. SOLLINGER, H.W. - Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S Renal Transplant Mycophenolate Mofetil Study Group. Transplantation, 60: 225-232, 1995.
10. THE TRICONTINENTAL MYCOPHENOLATE MOFETIL RENAL TRANSPLANTATION STUDY GROUP - A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation. Transplantation, 61: 1029-1037, 1996.