Functional outcome and clinical significance of long-term intrathecal baclofen therapy for severe spasticity

Neurorehabilitation and Neural Repair

Volumn 10, Issue 3, 1996, Pages 159-166

  Ochs, Günter A ^a   Tonn, Jörg C ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Department of Neurosurgery ^*  (Germany)

Author keywords

Drug delivery systems; Functional changes; Intrathecal baclofen; Spasticity

Indexed keywords

EID: 21444443135     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/154596839601000303     Document Type: Article

References (41)

1. L. Bowery NG, Bittiger H., Olpe HR Gaba-B receptors in mammalian function. Chichester: John Wiley & Sons, 1990.
2. Penn RD, Kroin JS Intrathecal baclofen alleviates spinal cord spasticity. Lancer 1954;1:1078.
3. Penn RD, Kroin JS Continuous intrathecal baclofen for severe spasticity. Lancet 1985;2:125-27.
4. Müller H., Börner U., Zierski J., Hempelmann G. Intrathecal baclofen in tetanus. Lancet 1986, 1:317-18.
5. Coffey RJ, Cahill D., Steers W.,et al.Intrathecal baclofen for intractable spasticity of spinal origin: results of a long-term multicenter study. J Neurosurg 1993;78:226-32.
6. Penn RD, Savoy SM, Corcos D.,et al.Intrathecal baclofen for severe spinal spasticity. N Enol J Med 1989;320:1517-21.
7. Penn RD Intrathecal baclofen for spasticity of spinal origin: seven. years of experience. J Neurosurg 1992;77:236-40.
8. Ochs G., Struppler A., Meyerson BA,et al.Intrathecal haclofen for long-term treatment of spasticity: a multi-centre study. J Neurol Neurosurg Psychiatry 1989; 52:933-39.
9. Ochs G., Delhaas EM Long-term experience with intrathecal use of baclofen in severe spasticity. In: Lakke JPWF, Delhaas EM, Rutgers AWF (eds.). Parenteral drug therapy in spasticity and Parkinson's disease. Lancaster, UK: Parthenon, 1992:87-102.
10. Albright AL, Cervi A., Singletary J. Intrathecal baclofen for spasticity in cerebral palsy. JAMA 1991;65:1415-22.
11. Albright AL, Barron WB, Fasick MP, Polinko P., Janosky J., Continuous intrathecal baclofen infusion for spasticity of cerebral origin. JAMA 1993;270:2475-77.
12. Meinck HM, Tronnier V., Rieke K., Wirtz CR, Flügel D., Schwab S. Intrathecal baclofen treatment for stiff-man syndrome: pump failure may be fatal. Neurology 1994;44:2209-10.
13. Saissy JM, Demaziere J., Vitris M.,et al.Treatment of severe tetanus by intrathecal injections of baclofen without artificial ventilation. Intensive Care Med 1992;18:241-44.
14. Sun KO, Chan YW, Cheung Rtf, So PC, Yu YL, Li Pck, Management of tetanus: a review of 18 cases. J Royal Soc Med 1994; 87:135-37.
15. Narayan RK, Loubser PG, Jankovic J., Donovan WH, Bontke CF Intrathecal baclofen for intractable axial dystonia. Neurology 1991;41:1141-42.
16. Greene PE, Fahn S. Baclofen in the treatment of idiopathic dystonia in children. Mov Dis 1992;7:48-52.
17. Jankovic J. Current approaches in the treatment of dystonia. In: Annual Seminars: Movement Disorders. Washington, D.C. American Academy of Neurology, 1994:375.
18. Ford B., Fahn S. i Penn RD, Intrathecal baclofen. Neurology 1994;44:1367-68.
19. Meinck HM, Ricker K., Hulser PJ, Schmid E., Peiffer J., Solimena M. Stiff man syndrome: clinical and laboratory findings in eight patients. J Neurol 1994;241:157-66.
20. Kums Jjm, Delhaas EM Intrathecal baclofen infusion in patients with spasticity and neurogenic bladder disease. Preliminary results. World J Urol 1991;9:153-56.
21. Kums Jjm. The spastic bladder and urodyhamic aspects. In: Lakke JPWF, Delhaas EM, Rutgers AWF (eds.). Parenteral drug therapy in spasticity and Parkinson's disease. Lancaster, UK: Parthenon, 1992:27-40.
22. Talalla A., Grundy D., Macdonell R. The effect of intrathecal baclofen on the lower urinary tract in paraplegia. Paraplegia 1990;28:420-27.
23. Frost F., Nanninga J., Penn R., Savoy S., Wu Y. Intrathecal baclofen infusion. Effect on bladder management programs in patients with myelopathy. Am J Phys Med Rehabil 1989; 68:112-15.
24. Denys P., Azouvi P., Jokic C., Mane M., Yakovleff A., Bussel B. Intrathecal baclofen spasticity and vesicosphincterian disorders in spinal cord diseases. Ann Readapt Med Phys 1993;36:365-72.
25. Nanninga JB, Frost F., Penn R. Effect of intrathecal baclofen on bladder and sphincter function. J Urol 1989;142:101-105.
26. Parke B., Penn RD, Savoy SM, Corcos D. Functional outcome after delivery of intrathecal baclofen. Arch Phys Med Rehabil 1989;70:30-32.
27. Ochs G. Intrathecal application of baclofen (Lioresal) in spasticity. In: Marsden D (ed.). Treating spasticity: pharmacological advances. Bern: Hans Huber Verlag, 1988:49-54.
28. H. Müller, J. Zierski, Penn RD Local-spinal therapy of spasticity. Berlin: Springer, 1988.
29. Bohannon RW, Smith MB Interrater reliability of a modified Ashworth scale of muslce spasticity. Physical Therapy 1987,67:206-207.
30. M. Sindou, R. Abbott, Keravel Y. Neurosurgery for spasticity-a multidisciplinary approach. Berlin: Springer, 1991.
31. Das TK Botulinum toxin in treating spasticity. BJCP 1989 43(11):401-403.
32. Dengler R., Neyer U., Wohlfarth K.,et al.Local botulinum toxin in the treatment of spastic drop foot. J Neurol 1992;239:375-78.
33. Hesse S., Friedrich H., Domasch C.,et al.Botulinum toxin therapy for upper limb flexor spasticity: preliminary results. J Rehabil Sci 1992;5:98-101.
34. Akman MN, Loubser PG, Donovan WH, O'Neill ME, Rossi CD Intrathecal baclofen: does tolerance occur? Paraplegia 1993; 31:516-20.
35. Müller H. Treatment of severe spasticity: results of a multicenter trial conducted in Germany involving the intrathecal infusion of baclofen by an implantable drug delivery system. In: Lakke JPWF, Delhaas EM, Rutgers AWF (eds.). Parenteral drug therapy in spasticity and Parkinson's disease. Lancaster, UK: Parthenon, 1992:103-13.
36. Ochs G., Weinzierl FX, Gudden W., Struppler A. Intrathekale Baclofen-Therapie bei Spastik. Akt Neurol 16:1989;133-37.
37. Penn RD, Kroin JS Long-term intrathecal baclofen infusion for treatment of spasticity. J Neurosurg 1987;66:181-85.
38. Romijn JA, van Lieshout JJ, Velis DN Reversible coma due to intrathecal baclofen. Lancet 1986;2:696.
39. Delhaas EM, Brouwers Jrbj. Intrathecal baclofen overdose: report of 7 events in 5 patients and review of the literature. Int J Clin-Pharmacol Ther Toxicol 1991;29:274-80.
40. Müller Schwefe G, Penn RD, Physostigmine in the treatment of intrathecal baclofen overdose. Report of three cases. J Neurosurg 1989; 71:273-75.
41. Rustemovic N., Huic M., Opacic M., Pulanic R., Vucelic B., Vrhovac B. Tizanidine-induced acute toxic hepatitis: case report. Pharmaca 1994;32:457-61.