Preoperative antibiotics and mortality in the elderly

Annals of Surgery

Volumn 242, Issue 1, 2005, Pages 107-114

  Silber, Jeffrey H ^a,b,c   Rosenbaum, Paul R ^d   Trudeau, Martha E ^a,e   Chen, Wei ^a,c   Zhang, Xuemei ^a   Lorch, Scott A ^a,b,c   Kelz, Rachel Rapaport ^f   Mosher, Rachel E ^a   Even Shoshan, Orit ^a,c  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT;

AGED; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DYING; FEMALE; GENERAL SURGERY; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICARE; MORTALITY; ORTHOPEDIC SURGERY; POSTOPERATIVE INFECTION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RISK REDUCTION;

AGE FACTORS; AGED; AGED, 80 AND OVER; ALGORITHMS; ANTIBIOTIC PROPHYLAXIS; CASE-CONTROL STUDIES; FEMALE; FOLLOW-UP STUDIES; GERIATRIC ASSESSMENT; HOSPITAL MORTALITY; HUMANS; LOGISTIC MODELS; MALE; MULTIVARIATE ANALYSIS; ORTHOPEDIC PROCEDURES; POSTOPERATIVE COMPLICATIONS; PREOPERATIVE CARE; PROBABILITY; REGISTRIES; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SEX FACTORS; SURGICAL PROCEDURES, OPERATIVE; SURGICAL WOUND INFECTION; SURVIVAL RATE;

EID: 21444442039     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.sla.0000167850.49819.ea     Document Type: Article

References (35)

1. Mangram AJ, Horan TC, Pearson ML, et al. Guidelines for prevention of surgical site infection, 1999. Infect Control Hosp Epidemiol. 1999;20: 247-278.
2. Pestotnik SL, Classen DC, Evans RS, et al. Implementing antibiotic practice guidelines through computer-assisted decision support: clinical and financial outcomes. Ann Intern Med. 1996;124:884-890.
3. Classen DC, Evan RS, Pestotnik SL, et al. The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection. N Engl J Med. 1992;326:281-286.
4. Stone HH. Basic principles in the use of prophylactic antibiotics. J Antimicrob Chemother. 1984;14:33-37.
5. Ronald AR. Antimicrobial prophylaxis in surgery. Surgery. 1983;93: 172-173.
6. Olson M, O'Connor M, Schwartz ML. Surgical wound infections: a 5-year prospective study of 20,193 wounds at the Minneapolis VA Medical Center. Ann Surg. 1984;199:253-259.
7. Nichols RL, Smith JW, Garcia RY, et al. Current practices of preoperative bowel preparation among North American colorectal surgeons. Clin Infect Dis. 1997;24:609-619.
8. Page CP, Bohnen JMA, Fletcher R, et al. Antimicrobial prophylaxis for surgical wounds: guidelines for clinical care. Arch Surg. 1993;128: 79-88.
9. Rotman N, Hay J-M, Lacaine F, et al. Prophylactic antibiotherapy in abdominal surgery. Arch Surg. 1989;124:323-327.
10. Kaiser AB. Antimicrobial prophylaxis in surgery. N Engl J Med. 1986;315:1129-1138.
11. Silber JH, Rosenbaum PR, Trudeau ME, et al. Multivariate matching and bias reduction in the surgical outcomes study. Med Care. 2001;39: 1048-1064.
12. Aiken LH, Clarke SP, Sloane DM, et al. Hospital nurse staffing and patient mortality, nurse burnout, and job dissatisfaction. JAMA. 2002; 288:1987-1993.
13. Guglielmo BJ, Hohn DC, Koo PJ, et al. Antibiotic prophylaxis in surgical procedures. Arch Surg. 1983;118:943-955.
14. Rosenbaum PR, Silber JH. Matching and thick description in observational study of mortality after surgery. Biostatistics. 2001;2:217-232.
15. 14a. Silber JH, Rosenbaum PR, Trudeau ME, et al. Changes in prognosis after the first postoperative complication. Medical Care. 2005;43:122-131.
16. Mantel N. Synthetic retrospective studies and related topics. Biometrics. 1973;29:479-486.
17. U.S. Department of Health and Human Services. Statistical Supplement 1997. Health Care Finance Rev. 1997:31.
18. U.S. Department of Health and Human Services. Statistical Supplement 1998. Health Care Finance Rev. 1998:177.
19. Steen PM, Brewster AC, Bradbury RC, et al. Predicted probabilities of hospital death as a measure of admission severity of illness. Inquiry. 1993;30:128-141.
20. Rosenbaum P, Rubin D. The central role of the propensity score in observational studies for causal effects. Biometrika. 1983;70:41-55.
21. Rosenbaum PR, Rubin DB. Constructing a control group using multivariate matched sampling methods that incorporate the propensity score. Am Stat. 1985;39:33-38.
22. Rubin DB. Bias reduction using Mahalanobis metric matching. Biometrics. 1980;36:293-298.
23. Rubin DB. Using multivariate matched sampling and regression adjustment to control bias in observational studies. J Am Stat Assoc. 1979;74: 318-328.
24. Knaus WA, Wagner DP, Draper EA, et al. The APACHE III prognostic system: risk prediction of hospital mortality for critically ill hospitalized adults. Chest. 1991;100:1619-1636.
25. McMahon LF, Hayward RA, Bernard AM, et al. APACHE-L: a new severity of illness adjuster for inpatient medical care. Med Care. 1992; 30:445-452.
26. Breslow NE, Day NE. Conditional logistic regression for matched sets. In: Davis W, ed. Statistical Methods in Cancer Research, vol. 1. The Analysis of Case-Control Studies. Lyon, France: International Agency for Research on Cancer of the World Health Organization, 1980:248-279.
27. MacMahon B, Trichopoulos D. Epidemiology: Principles and Methods, 2nd ed. Boston: Little, Brown, 1996.
28. Holford T, White C, Kelsey J. Multivariate analysis for matched case-control studies. Am J Epidemiol. 1978;107:245-256.
29. Gastwirth JL, Krieger AM, Rosenbaum PR. Cornfield's inequality. In: Armitage P, Colton T, eds. Encyclopedia of Biostatistics, vol. 1. New York: John Wiley; 1998:952-955.
30. Gastwirth JL, Krieger AM, Rosenbaum PR. Dual and simultaneous sensitivity analysis for matched pairs. Biometrika. 1998;85:907-920.
31. Pavel A, Smith RL, Ballard A, et al. Prophylactic antibiotics in clean orthopaedic surgery. J Bone Joint Surg Am. 1974;56:777-782.
32. Pollard JP, Hughes SPF, Scott JE, et al. Antibiotics prophylaxis in total hip replacement. BMJ. 1979;1:707-709.
33. Hill C, Flamant R, Mazas F, et al. Prophylactic cefazolin versus placebo in total hip replacement: report of a multicentre double-blind randomised trial. Lancet. 1981;1:795-796.
34. Trudeau M, Kuhr L, Solano-McGuire S. Timing of preoperative prophylactic antibiotics: old project and still improving. Am J Infect Control. 1998;26:581-583.
35. Impallomeni M, Galletly NP, Wort SJ, et al. Increased risk of diarrhoea caused by Clostridium difficile in elderly patients receiving cefotaxime. Br Med J. 1995;311:1345-1346.