RBE of carbon ions: Experimental data and the strategy of RBE calculation for treatment planning

Radiotherapy and Oncology

Volumn 73, Issue SUPPL. 2, 2004, Pages

  Weyrather, W K ^a,b   Kraft, G ^a,b  

^a GSI HELMHOLTZZENTRUM FÜR SCHWERIONENFORSCHUNG GMBH   (Germany)

^b NONE   (Germany)

Author keywords

Intensity Modulated Particle Therapy IMPT Cell repair and RBE lon beam therapy; Local Effect Model LEM; Relative Biological Effectiveness RBE

Indexed keywords

CARBON; HEAVY ION;

CALCULATION; CANCER RADIOTHERAPY; CELL NUCLEUS; CELL REGENERATION; CELL SURVIVAL; CELL TYPE; CONFERENCE PAPER; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MATHEMATICAL MODEL; NONHUMAN; OXYGEN ENHANCEMENT RATIO; POISSON DISTRIBUTION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIOSENSITIVITY; RELATIVE BIOLOGIC EFFECTIVENESS; THEORETICAL STUDY; TREATMENT PLANNING; ANIMAL; ARTICLE; CHO CELL; COMPUTER ASSISTED RADIOTHERAPY; HAMSTER; LINEAR ENERGY TRANSFER;

ANIMALS; CARBON; CHO CELLS; CRICETINAE; HEAVY IONS; HUMANS; LINEAR ENERGY TRANSFER; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RELATIVE BIOLOGICAL EFFECTIVENESS;

EID: 21444441734     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-8140(04)80041-0     Document Type: Conference Paper

References (20)

1. Wambersie A. The Future of High-LET Radiation in Cancer Therapy Chauvel P Wambersie A. Eulima Workshop on the Potential Value of Light Ion Beam Therapy Publication No. EUR 12165 1989 Commission of the European Community Washington DC
2. Kraft G. Radiobiology of Heavy Charged Particles Amaldi U. Larsson B. Lemoigne Y. Advances in Hadrontherapy Excerpta Medica, Int. Congr. Series 1144 1997 Elsevier Brussels 385 404
3. Weyrather W.K., Ritter S., Scholz M., and Kraft G. RBE for Track-Segment Irradiation in Cell Lines of Differing Repair Capacity Int. J. Radiat. Biol. 75 1999 1357 1364
4. Kraft G. Tumor Therapy with Heavy Charged Ions Progr. Part. Nucl. Phys. 45 2000 473 544
5. Kraft G. RBE and its Interpretation Strahlenther. Onkol. 175 Suppl 2 1999 44 47
6. Belli M., Cera F., and Cherubini R. RBE-LET Relationships for Cell Inactivation and Mutation Induced by Low energy Protons in V79 cells: Further Results at the LNL facility Int. J. of Radiat. Biol. 74 1998 501 509
7. Folkard M., Prise K.M., Vojnovic B., and Michael B.D. Inactivation of V79 Cells by Low Energy Protons, Deuterons and Helium-3 Ions Int. J. of Radiat. Biol. 69 1996 729 738
8. Kraft G. Radiobiological effect of very heavy ions Nucl. Sci. Appl. 3 1987 1 28
9. Kiefer J., Schmidt P., and Koch S. Mutations in Mammalian Cells Induced by Heavy charged Particles: An Indicator for Risk Assessment in Space Radiat. Res. 156 2001 607 611
10. Blakely E.A., Tobias C.A., Ngo F.Q.H., and Curtis S.B. Physical and Cellular Radiobiological Properties of Heavy Ions in Relation to Cancer Therapy Application Pirncello M.D. Tobias C.A. Biological and Medical Research with Accelerated Heavy Ions at the Bevalac LBL 11220 1980 73 88
11. Furusawa Y., Fukutsu M., and Aoki M. Inactivation of Aerobic and Hypoxic Cells from Three Different Cell Lines by Accelerated 3He-, 12C- and 20Ne-Ion Beams Radiat. Res. 145 2000 485 496
12. Hall E. Radiobiology for the Radiologist 1994 Lipincott Company
13. Weyrather W.K. Radiobiological Research for Hadron Therapy Kogelnik H.D. Lukas P. Sedlmayer F. Progress in Radio-Oncology VII Monduzzi Editore 2002 353 360
14. Suzuki M., Kase Y., and Yamaguchi H. Relative Biological Effectiveness for Cell-Killing Effect on Various Human Cell Lines Irradiated with Heavy-Ion Medical Accelerator in Chiba (HIMAC) Carbon-Ions Beams Int. J. Radiat. Oncol. Biol. Phys. 48 2000 241 250
15. Scholz M., and Kraft G. Calculation of Heavy Ion Inactivation Probabilities Based on Track Structure, X-ray Sensitivity and Target Size Radiat. Prot. Dosimetry Vol. 52 No. 1-4 1994 29 33
16. Scholz M., Kellerer A.M., Kraft-Weyrather W., and Kraft G. Computation of Cell Survival in Heavy-Ion Beams for Therapy. The Model and its Approximation Radiat. Environ. Biophys. 36 1997 59 66
17. Scholz M. Effect of Ion Radiation on Cells and Tissues Advances in Polymer Science 162 2003 95 155
18. Scholz M., and Kraft G. Track Structure and the Calculation of Biological Effects of Heavy Charged Particles Adv. Space Res. 18 1996 5 14
19. Castro J.R. Clinical Results in Heavy Particles Radiotherapy LBL 11220 1980 305 318
20. Krämer M., and Scholz M. Treatment Planning for Heavy Ion Radiotherapy Phys. Med. Biol. 45 2000 3319 3330