Peptides selected for binding to a virulent strain of Haemophilus influenzae by phage display are bactericidal

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 7, 2005, Pages 2972-2978

  Bishop Hurley, Sharon L ^a   Schmidt, Francis J ^b   Erwin, Alice L ^c   Smith, Arnold L ^c  

^a CSIRO   (Australia)

^b University of Missouri   (United States)

^c SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN 2; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CATION; DEFENSIN HNP 1; MAGAININ 2; POLYMYXIN B; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATE; BRONCHITIS; CELL SURFACE; CLONE; DOSE RESPONSE; ENTEROCOCCUS FAECALIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HAEMOPHILUS INFLUENZAE; HAEMOPHILUS INFLUENZAE TYPE B; NONHUMAN; OROPHARYNX; OTITIS MEDIA; PHAGE DISPLAY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEUS MIRABILIS; PSEUDOMONAS AERUGINOSA; SALMONELLA ENTERICA; SINUSITIS; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; HAEMOPHILUS INFLUENZAE; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES; VIRULENCE;

EID: 21444438641     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.7.2972-2978.2005     Document Type: Article

References (37)

1. Akerley, B. J., E. J. Rubin, V. L. Novick, K. Amaya, N. Judson, and J. J. Mekalanos. 2002. A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae. Proc. Natl. Acad. Sci. US A 99:966-971.
2. Balass, M., Y. Heldman, S. Cabilly, D. Givol, E. Katchalski-Katzir, and S. Fuchs. 1993. Identification of a hexapeptide that mimics a conformation-dependent binding site of acetylcholine receptor by use of a phage-epitope library. Proc. Natl. Acad. Sci. USA 90:10638-10642.
3. Bayliss, C. D., D. Field, and E. R. Moxon. 2001. The simple sequence contingency loci of Haemophilus influenzae and Neisseria meningitidis. J. Clin. Investig. 107:657-662.
4. Bishop-Hurley, S. L., S. A. Mounter, J. Laskey, R. O. Morris, J. Elder, P. Roop, C. Rouse, F. J. Schmidt, and J. T. English. 2002. Phage-displayed peptides as developmental agonists for Phytophthora capsici zoospores. Appl. Environ. Microbiol. 68:3315-3320.
5. Brenner, D. J., L. W. Mayer, G. M. Carlone, L. H. Harrison, W. F. Bibb, M. C. Brandileone, F. O. Sottnek, K. Irino, M. W. Reeves, and J. M. Swenson. 1988. Biochemical, genetic, and epidemiologic characterization of Haemophilus influenzae biogroup aegyptius (Haemophilus aegyptius) strains associated with Brazilian purpuric fever. J. Clin. Microbiol. 26:1524-1534.
6. Cerquetti, M., M. L. Ciofi degli Atti, G. Renna, A. E. Tozzi, M. L. Garlaschi, P. Mastrantonio, et al. 2000. Characterization of non-type B Haemophilus influenzae strains isolated from patients with invasive disease. J. Clin. Microbiol. 38:4649-4652.
7. Christensen, D. J., E. B. Gottlin, R. E. Benson, and P. T. Hamilton. 2001. Phage display for target-based antibacterial drug discovery. Drug Discov. Today 6:721-727.
8. Cwirla, S. E., E. A. Peters, R. W. Barrett, and W. J. Dower. 1990. Peptides on phage: a vast library of peptides for identifying ligands. Proc. Natl. Acad. Sci. USA 87:6378-6382.
9. Da, S. A., Jr., U. Kawazoe, F. F. Freitas, M. S. Gatti, H. Dolder, R. I. Schumacher, M. A. Juliano, M. J. da Silva, and A. Leite. 2002. Avian anticoccidial activity of a novel membrane-interactive peptide selected from phage display libraries. Mol. Biochem. Parasitol. 120:53-60.
10. Fleischmann, R. D., M. D. Adams, O. White, R. A. Clayton, E. F. Kirkness, A. R. Kerlavage, C. J. Bult, J. F. Tomb, B. A. Dougherty, and J. M. Merrick. 1995. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269:496-512.
11. Foxwell, A. R., J. M. Kyd, and A. W. Cripps. 1998. Nontypeable Haemophilus influenzae: pathogenesis and prevention. Microbiol. Mol. Biol. Rev. 62:294-308.
12. Ganz, T., M. E. Selsted, D. Szklarek, S. S. Harwig, K. Daher, D. F. Bainton, and R. I. Lehrer. 1985. Defensins: natural peptide antibiotics of human neutrophils. J. Clin. Investig. 76:1427-1435.
13. Hiemstra, P. S., and R. Bals. 2004. Series introduction: innate host defense of the respiratory epithelium. J. Leukoc. Biol. 75:3-4.
14. Holmes, R. L., L. M. DeFranco, and M. Otto. 1982. Novel method of biotyping Haemophilus influenzae that uses API 20e. J. Clin. Microbiol. 15:1150-1152.
15. Hoogenboom, H. R., J. T. Lutgerink, M. M. Pelsers, M. J. Rousch, J. Coote, N. Van Neer, A. De Bruine, F. A. Van Nieuwenhoven, J. F. Glatz, and J. W. Arends. 1999. Selection-dominant and nonaccessible epitopes on cell-surface receptors revealed by cell-panning with a large phage antibody library. Eur. J. Biochem. 260:774-784.
16. Ishiwada, N., L. D. Cao, and Y. Kohno. 2004. PCR-based capsular serotype determination of Haemophilus influenzae strains recovered from Japanese paediatric patients with invasive infection. Clin. Microbiol. Infect. 10:895-898.
17. Kilian, M. 1976. A taxonomic study of the genus Haemophilus, with the proposal of a new species. J. Gen. Microbiol. 93:9-62.
18. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
19. Lee, H. Y., A. Andalibi, P. Webster, S. K. Moon, K. Teufert, S. H. Kang, J. D. Li, M. Nagura, T. Ganz, and D. J. Lim. 2004. Antimicrobial activity of innate immune molecules against Streptococcus pneumoniae, Moraxella catarrhalis and nontypeable Haemophilus influenzae. BMC Infect. Dis. 4:12.
20. Lee, K. H. 2002. Development of short antimicrobial peptides derived from host defense peptides or by combinatorial libraries. Curr. Pharm. Des. 8:795-813.
21. Meats, E., E. J. Feil, S. Stringer, A. J. Cody, R. Goldstein, J. S. Kroll, T. Popovic, and B. G. Spratt. 2003. Characterization of encapsulated and non-capsulated Haemophilus influenzae and determination of phylogenetic relationships by multilocus sequence typing. J. Clin. Microbiol. 41:1623-1636.
22. 21a. Mhlangal-Mutangadura, T., G. Morlin, A. L. Smith, A. Eisenstark, and M. Golomb. 1998. Evolution of the major pilus gene cluster of Haemophilus influenzae. J. Bacteriol. 180:4693-4703.
23. Moser, C., D. J. Weiner, E. Lysenko, R. Bals, J. N. Weiser, and J. M. Wilson. 2002. β-Defensin-1 contributes to pulmonary innate immunity in mice. Infect. Immun. 70:3068-3072.
24. Murphy, T. F., and M. A. Apicella. 1987. Nontypeable Haemophilus influenzae: a review of clinical aspects, surface antigens, and the human immune response to infection. Rev. Infect. Dis. 9:1-15.
25. Nizet, V., K. F. Colina, J. R. Almquist, C. E. Rubens, and A. L. Smith. 1996. A virulent nonencapsulated Haemophilus influenzae. J. Infect. Dis. 173:180-186.
26. O'Neill, J. M., J. W. St. Geme III, D. Cutter, E. E. Adderson, J. Anyanwu, R. F. Jacobs, and G. E. Schutze. 2003. Invasive disease due to nontypeable Haemophilus influenzae among children in Arkansas. J. Clin. Microbiol. 41:3064-3069.
27. Poolman, J. T., L. Bakaletz, A. Cripps, P. A. Denoel, A. Forsgren, J. Kyd, and Y. Lobet. 2000. Developing a nontypeable Haemophilus influenzae (NTHi) vaccine. Vaccine 19(Suppl. 1):S108-S115.
28. Reilly, T. J., and A. L. Smith. 1999. Purification and characterization of a recombinant Haemophilus influenzae outer membrane phosphomonoesterase e (P4). Protein Expr. Purif. 17:401-409.
29. Saggio, I., and R. Laufer. 1993. Biotin binders selected from a random peptide library expressed on phage. Biochem. J. 293(Pt. 3):613-616.
30. Schutte, B. C., and P. B. McCray, Jr. 2002. β-Defensins in lung host defense. Annu. Rev. Physiol. 64:709-748.
31. Scott, J. K., and G. P. Smith. 1990. Searching for peptide ligands with an epitope library. Science 249:386-390.
32. Smith, G. P., and V. A. Petrenko. 1997. Phage display. Chem. Rev. 97:391-410.
33. Starner, T. D., W. E. Swords, M. A. Apicella, and P. B. McCray, Jr. 2002. Susceptibility of nontypeable Haemophilus influenzae to human beta-defensins is influenced by lipooligosaccharide acylation. Infect. Immun. 70:5287-5289.
34. Thompson, J. D., D. G. Higgins, and T. J. Gibson. 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties, and weight matrix choice. Nucleic Acids Res. 22:4673-4680.
35. Turnak, M. R., S. I. Bandak, S. K. Bouchillon, B. S. Allen, and D. J. Hoban. 2001. Antimicrobial susceptibilities of clinical isolates of Haemophilus influenzae and Moraxella catarrhalis collected during 1999-2000 from 13 countries. Clin. Microbiol. Infect. 7:671-677.
36. Yu, J., and G. P. Smith. 1996. Affinity maturation of phage-displayed peptide ligands. Methods Enzymol. 267:3-27.
37. Zasloff, M. 2002. Antimicrobial peptides of multicellular organisms. Nature 415:389-395.