Acephate in biological fluids of two autopsy cases after ingestion of the chemical

Journal of Forensic Sciences

Volumn 50, Issue 4, 2005, Pages 933-936

  Tanaka, Toshiko ^a   Tanaka, Noriyuki ^a   Kita, Toshiro ^a   Kasai, Kentaro ^a   Sato, Hiroaki ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Acephate; Acute poisoning; Analysis; Forensic science; GC MS; Methamidophos (MP); Organophosphate (OP)

Indexed keywords

ACEPHATE; CHOLINESTERASE; DRUG METABOLITE; METHAMIDOPHOS; ORGANOPHOSPHATE INSECTICIDE;

ADULT; AGED; ANALYTIC METHOD; ARTICLE; AUTOPSY; CASE REPORT; CAUSE OF DEATH; CHOLINESTERASE INHIBITION; CONCENTRATION (PARAMETERS); DRUG DETERMINATION; ENZYME ACTIVITY; FORENSIC MEDICINE; GAS CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; INGESTION; LIQUID LIQUID EXTRACTION; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL;

EID: 21444438470     PISSN: 00221198     EISSN: None     Source Type: Journal    
DOI: 10.1520/jfs2004172     Document Type: Article

References (18)

1. Bull DL. Fate and efficacy of acephate after application to plants and insects. J Agric Food Chem 1979;27(2):268-72.
2. Kao TS, Fukuto TR. Metabolism of O, S dimethyl propionyl- and hexanoylphophor-amidethioate in the housefly and white mouse. Pestic Biochem Physiol 1977;7:83-95.
3. Hussain MA. Anticholinesterase properties of methamidophos and acephate in insects and mammals. Bull Environ Contam Toxicol 1987; 38(1):131-8.
4. Mahajna M, Quistad GB, Casida JE. Acephate insecticide toxicity: safety conferred by inhibition of the bioactivating carboxyamidase by the metabolite methamidophos. Chem Res Toxicol 1997;10(1): 64-9.
5. FAO. 1976 Evaluation of some pesticide residues in food. The monographs. ACEPHATE. FAO plant production and protection series n.8: 1-54-Rome. FAO, 1977.
6. Maroni M, Catenacci G, Galli D, Cavallo D, Ravazzani G. Biological monitoring of human exposure to acephate. Arch Environ Contam Toxicol 1990;19(5):782-8.
7. Ames RG, Brown SK, Mengle DC, Kahn E, Stratton JW, Jackson RJ. Cholinesterase activity depression among California agricultural pesticide applicators. Am J Ind Med 1989;15(2):143-50.
8. Panemangalore M, Dowla HA, Byers ME. Occupational exposure to agricultural chemicals: effect on the activities of some enzymes in the blood of farm workers. Int Arch Occup Environ Health 1999;72(2): 84-8.
9. Guven M, Unluhizarci K, Goktas Z, Kurtoglu S. Intravenous organophosphate injection: an unusual way of intoxication. Hum Exp Toxicol 1997;16(5):279-80.
10. Ellman GL, Courtney KD, Andres V, Jr., Feather-Stone RM. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961;7:88-95.
11. Faller-Marquardt M, Pollak S. [Effect of environmental temperature on the course of spontaneous postmortem pupillary changes (studies of the rabbit eye)]. Beitr Gerichtl Med 1992;50:325-32.
12. Klette KL, Levine B, Dreka C, Smith ML, Goldberger BA. Cholinesterase activity in postmortem blood as a screening test for organophosphate/chemical weapon exposure. J Forensic Sci 1993;38(4): 950-5.
13. Lanks KW, Sklar GS. Stability of pseudocholinesterase in stored blood. Anesthesiology 1976;44(5):428-30.
14. Tomlin C. The pesticide manual. A world compendium. 10th ed. Surrey: The British Crop Protection Council, 1994.
15. Ellenhom MJ, Schonwald S, Ordog G, Wasserberger J. Ellenhom's medical toxicology: diagnosis and treatment of human poisoning. 2nd ed. Hagerstown: Lippincott Williams & Wilkins, 1996.
16. Baselt R. Disposition of toxic drugs and chemicals in man. 7th ed. Foster City, California: Biomedical Publications, 2004.
17. Ando M, Wakamatsu K. Inhibitory effect of acephate (N-acetyl O, S-dimethyl thiophosphoramide) on serum cholinesterase-effect of acephate on cholinesterase. J Toxicol Sci 1982;7(3):185-92.
18. Dowla HA, Panemangalore M, Byers ME. Comparative inhibition of enzymes of human erythrocytes and plasma in vitro by agricultural chemicals. Arch Environ Contam Toxicol 1996;31(1):107-14.