Effects of low energy protons on clonogenic survival, DSB repair and cell cycle in human glioblastoma cells and B14 fibroblasts

Radiotherapy and Oncology

Volumn 73, Issue SUPPL. 2, 2004, Pages

  Moertel, Heinrich ^a   Georgi, Jens Christoph ^b   Distel, Luitpold ^a   Eyrich, Wolfgang ^b   Fritsch, Miriam ^b   Grabenbauer, Gerhard ^a   Sauer, Rolf ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

B14 fibroblasts; Cell cycle control; DSB; Glioblastoma cells; Proton irradiation; RBE

Indexed keywords

DOUBLE STRANDED DNA; PROTON;

ANIMAL CELL; CELL CYCLE; CELL CYCLE G2 PHASE; CELL LINE; CELL SURVIVAL; CLONOGENESIS; COLONY FORMING UNIT; CONFERENCE PAPER; DNA REPAIR; DNA STRAND BREAKAGE; DOSE RESPONSE; FIBROBLAST; GEL ELECTROPHORESIS; GLIOBLASTOMA; GLIOMA CELL; HAMSTER; HUMAN; HUMAN CELL; IMAGE CYTOMETRY; LINEAR ENERGY TRANSFER; LOW ENERGY RADIATION; NONHUMAN; PRIORITY JOURNAL; PROTON RADIATION; TUMOR CELL; X IRRADIATION; ARTICLE; DNA DAMAGE; GENETICS; PATHOLOGY; RADIATION EXPOSURE; RELATIVE BIOLOGIC EFFECTIVENESS;

CELL CYCLE; CELL SURVIVAL; DNA DAMAGE; DNA REPAIR; GLIOBLASTOMA; HUMANS; PROTONS; RELATIVE BIOLOGICAL EFFECTIVENESS;

EID: 21444434274     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-8140(04)80030-6     Document Type: Conference Paper

References (9)

1. Belli M, Cera F, and Cherubini R Inactivation and mutation induction in V79 cells by low energy protons: re-evaluation of the results at the LNL facility Int. J. Radiat. Biol. 63 3 1993 331 337
2. Belli M, Cera F, and Cherubini R RBE-LET relationships for cell inactivation and mutation induced by low energy protons in V79 cells: further results at the LNL facility Int. J. Radiat. Biol. 74 4 1998 501 509
3. Belli M, Bettega D, and Calzolari P Inactivation of human normal and tumor cells irradiated with low energy protons Int. J. Radiat. Biol. 76 6 2000 831 838
4. Belli M, Cherubini R, and Dalla Vecchia M DNA fragmentation in mammalian cells exposed to various light ions Adv. Space Res. 27 2 2001 393 399
5. Bettega D, Birattari C, and Bombana M Relative Biological Effectiveness for protons of energies up to 31 MeV Radiat. Res. 77 1979 85 97
6. Moertel H, Georgi J-Ch, Eyrich W, Fritsch M, and Distel L Automation of the particle dosimetry and the dose application for radiobiological experiments at a vertical proton beam Nucl. Instr. Meth. A 89 3 2002 503 508
7. Orecchia R, Zurlo A, and Loasses A Particle Therapy (Hadrontherapy): Basis for Interest and Clinical Experience Eur. J. Cancer 34 4 1998 459 468
8. Paganetti H, and Goitein M Biophysical modeling of proton radiation effects based on amorphous track models Int. J. Radiat. Biol. 77 9 2001 911 928
9. Piasecka A, Distel L, and Schuessler H Analysis of radiation- and 5-FU-induced inhibition of cell proliferation by an automatic colony analyzer Int. J. Radiat. Biol. 74 1 1998 139 144